Reposted by Andrea Estandía
New paper with Trang Nguyen!
Do you have only a single parent and offspring, but still want to calculate mutation rates? We've got the tool for you--OOPS
github.com/TrangNg-Th/O...
www.biorxiv.org/content/10.6...
biorxiv.org
Estimating de novo mutation rates using parent-offspring pairs
Existing pedigree approaches to identifying de novo mutations (DNMs) require at least two parents and a single offspring, limiting applicability. Here, we introduce OOPS (Only One Parent Sequencing), ...
