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András Tálas

@andrastalas.bsky.social
22 followers 32 following 18 posts

Postdoctoral Fellow at @UZH in @schwanklab

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Martin Pacesa @martinpacesa.bsky.social · 04/08/2026
We are looking for a lab manager starting from January 2027, you can find more information on our members page pacesalab.com#members. We are also starting to look into hosting master students starting 2027.
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András Tálas @andrastalas.bsky.social · 13/05/2026
Today in @ScienceTranslationalMedicine, we report an in vivo prime editing strategy that corrects a disease-causing mutation and rescues phenotypes in a mouse model of citrullinemia type 1 (CTLN1), a devastating and often lethal liver disease. www.science.org/doi/10.1126/... (1)
science.org
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Reposted by András Tálas
Connor Tou @connorjtou.bsky.social · 11/03/2026
Today in @nature.com we introduce INSTALL, which bypasses mammalian DNA immune sensing to enable non-viral DNA integration with recombinases—a step toward safe, and mutation-agnostic genome editing. 🧬 🧵 (1/13) www.nature.com/articles/s41... @harvardmed.bsky.social @mgbresearch.bsky.social
nature.com
Immune evasive DNA donors and recombinases license kilobase-scale writing - Nature
INSTALL overcomes fundamental challenges for DNA delivery and integration methods by synergizing immune-stealth nucleic acids with recombinases to enable kilobase-scale integration strategies without ...
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András Tálas @andrastalas.bsky.social · 05/02/2026
Very cool work published in @science.org led by OanaPelea, happy to participate! www.science.org/doi/10.1126/...
media.tenor.com
a man wearing a beanie and a black jacket is smiling and holding a piece of food .
ALT: a man wearing a beanie and a black jacket is smiling and holding a piece of food .
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András Tálas @andrastalas.bsky.social · 20/05/2025
Our paper describing an RNA-LNP prime editing strategy for treating phenylketonuria was published today in Nature Biomedical Engineering (1/7) www.nature.com/articles/s41... @schwanklab @UZH_Science @UZH_en @KispiZuerich @ethz.ch
nature.com
Treatment of a metabolic liver disease in mice with a transient prime editing approach - Nature Biomedical Engineering
A transient in vivo prime editing strategy is developed for the liver by delivering the prime editor as mRNA encapsulated in LNP.
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