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Abdulmunaim Eid @ameid.bsky.social · 09/12/2025

d. Result (3): Brain morphometry predicts behavioral change in the Cognitive & Motor subtype. e. Conclusion: Biological differences underlie PD subtypes and may inform clinical & research decisions. 3/3

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Abdulmunaim Eid @ameid.bsky.social · 09/12/2025

Highlights: a. Introduction: Multi-domain PD subtypes capture its clinical heterogeneity. b. Result (1): Distinct baseline brain morphometric patterns differentiate PD clinical subtypes. c. Result (2): PD clinical subtypes demonstrate different longitudinal rates of atrophy. 2/3

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Abdulmunaim Eid @ameid.bsky.social · 26/10/2025

If you’re around St. Louis and interested in learning about Lewy body dementias (Parkinson disease dementia & Dementia with Lewy bodies), join us on Nov. 6.

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Abdulmunaim Eid @ameid.bsky.social · 09/10/2025

Riding back to Honolulu airport after attending & presenting at the #MDSCongress. Charles, the Lyft driver, has a theme for every 2 months of the year. This is Oct-Nov Halloween Mario theme. He also takes it upon himself to teach passengers something about Hawaii. Great conference & great Lyft ride!

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Abdulmunaim Eid @ameid.bsky.social · 06/10/2025

It was a much less organic experience than it should be. I don't know if this choice was the convention center's or the MDS, but either way I think if you do a survey, the majority would prefer the traditional poster experience. Amazing conference nevertheless! 3/3

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Abdulmunaim Eid @ameid.bsky.social · 06/10/2025

The electronic format limits/virtually eliminates the interaction between the presenters and those who are viewing the posters which is essential for the networking aspect and also for the scientific discussion of the material. Also, the sound on the phone was often delayed and cutting off. 2/3

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Abdulmunaim Eid @ameid.bsky.social · 06/10/2025

Great sessions in @movedisorder.bsky.social congress in #Honolulu with outstanding speakers and excellent organization. I must say, however, that the poster session is a disaster. The traditional way works much better. 1/3

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Abdulmunaim Eid @ameid.bsky.social · 08/08/2025

I think a clear question, solid methods & solid argument advance science most regardless of the story completeness. What is harming science is pushing scientists to publish frequently or in high IF journals leading to "manipulating/inflating" the question, methods, and argument, and hiding truth.

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Abdulmunaim Eid @ameid.bsky.social · 17/07/2025

To my knowledge, there was no discussion or mention to cognitive impairment or dementia in the context of gabapentin/pregabalin in the recent RLS guidelines. I think this is something I'm going to discuss with patients going forward. 5/5

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Abdulmunaim Eid @ameid.bsky.social · 17/07/2025

Nevertheless, this is an important study that makes us think about chronic gabapentin use. In restless leg syndrome, for example, recent guidelines bumped gabapentin & pregabalin up to the first-line treatment spot because of augmentation & other side effects associated with dopamine agonists. 4/5

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Abdulmunaim Eid @ameid.bsky.social · 17/07/2025

Given this and the inflammation and hemodynamic and biochemical changes associated with surgery and anesthesia, it is plausible that surgery in younger patients is also a risk for cognitive decline later in life. Thus, I would have loved to see surgery included in the propensity matching. 3/5

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Abdulmunaim Eid @ameid.bsky.social · 17/07/2025

The authors include multiple categories of medications and chronic diseases known to contribute to dementia risk, but not surgery which we know from studies and clinical practice that it increases the risk for delirium and long-term cognitive decline in the elderly. 2/5

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Abdulmunaim Eid @ameid.bsky.social · 17/07/2025

This is an important study that agrees with previous reports suggesting gabapentin & pregabalin use as a risk factor for cognitive impairment and dementia. My only major concern is that spinal and orthopedic surgery or surgery in general was not used in the propensity score matching procedure. 1/5

doi.org

Risk of dementia following gabapentin prescription in chronic low back pain patients

Introduction Gabapentin is widely used to treat chronic pain, but its association with cognitive decline and dementia remains unclear. This study examined whether gabapentin prescription is associated...

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Abdulmunaim Eid @ameid.bsky.social · 15/07/2025

A balanced and well-researched article on clozapine for Parkinson disease psychosis in light of the new FDA removal of required blood count monitoring. doi.org/10.1002/mds....

doi.org

The FDA Has Ended Required Blood Monitoring for Clozapine Use—Will This Impact the Management of Parkinson's Disease Psychosis?

Click on the article title to read more.

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Abdulmunaim Eid @ameid.bsky.social · 11/07/2025

Amazing work led by our collaborator and brilliant PhD student Jake Chernicky.

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Abdulmunaim Eid @ameid.bsky.social · 09/06/2025

I just signed the open letter in support of the Bethesda Declaration

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Abdulmunaim Eid @ameid.bsky.social · 17/03/2025

Do you recommend it as an add-on to preventives? And, how much do you typically recommend?

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Abdulmunaim Eid @ameid.bsky.social · 16/03/2025

Our review 'Update on the Treatment of Autonomic Disorders' just got published. We discuss non-pharmacological, pharmacological, and neuromodulatory and device options for autonomic disorders in a very clinic-oriented way. This is an important topic for neurologists and primary care physicians.

link.springer.com

Update on the Treatment of Autonomic Disorders - Current Treatment Options in Neurology

Purposeof Review Autonomic disorders disrupt homeostasis and cause symptoms such as orthostatic hypotension, urinary urgency, bladder overfilling, sexual dysfunction, constipation, and gastroparesis. ...

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Reposted by Abdulmunaim Eid

Masud Husain @masudhusain.bsky.social · 06/03/2025

Why academia is sleepwalking into self-destruction. My editorial @brain1878.bsky.social If you agree with the sentiments please repost. It's important for all our sakes to stop the madness academic.oup.com/brain/articl...

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Reposted by Abdulmunaim Eid

Michael Okun @michaelokun.bsky.social · 28/02/2025

Mind-blowing case of the day. This guy w/ Parkinson's has a left leg amputation. Later he develops phantom dystonia in the region of the missing limb? Eid, Rodrigo, and Norris teach us about the phenomenon through a case they published in the Movement Disorders Clinical Practice Journal.

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Abdulmunaim Eid @ameid.bsky.social · 26/02/2025

Our report on PD-Related Phantom Dystonia in an Amputated Limb just got published in @mdcp-journal.bsky.social. Fascinating phenomenon; to my knowledge, never been reported before though other reported phenomena e.g. virtual dystonia are possibly related. PDF: onlinelibrary.wiley.com/share/author...

movementdisorders.onlinelibrary.wiley.com

Parkinson Disease‐Related Phantom Dystonia in an Amputated Limb

Click on the article title to read more.

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Abdulmunaim Eid @ameid.bsky.social · 23/02/2025

Great guidance for caregivers; particularly applicable to Alzheimer disease

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Abdulmunaim Eid @ameid.bsky.social · 03/02/2025

In my opinion, these aspects should be left to society to organize (NOT to corporations OR governments). Of course, a sort of supervisory power exercised by the government is always needed, but that should be kept to a minimum. 2/2

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Abdulmunaim Eid @ameid.bsky.social · 03/02/2025

Like most, I’m worried about the course of action the new US administration is taking towards scientific activity and healthcare. However, I don’t think the appropriate long-term response is to ensure administrations take a different course in the future. 1/2

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Abdulmunaim Eid @ameid.bsky.social · 28/01/2025

The reduced striatal & normal cortical metabolism (FDG PET) make neurodegenerative diseases much less likely and the negative Aβ PET virtually excludes Alzheimer disease in particular, thus pointing to the effect of isolated vascular changes in the basal ganglia on cognition.

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Abdulmunaim Eid @ameid.bsky.social · 28/01/2025

Led by Dr. Erika Weil, we publish a report in Neurology highlighting a patient with striatal ePVSs (beautifully captured on 7T MRI) likely responsible for her impaired executive function as suggested by reduced striatal & normal cortical metabolism (FDG PET) and neg Aβ PET. doi.org/10.1212/WNL....

doi.org

État Criblé | Neurology

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Reposted by Abdulmunaim Eid

Andreas Horn @andreashorn.org · 08/01/2025

🚨Interested in Dystonia?🚨 @braincircuits.bsky.social GPi DBS for dystonia is effective. More recently, STN DBS has been investigated, as an alternative. In what enfolded like a stunning thriller to me, Konstantin Butenko tells a tale of two networks… www.pnas.org/doi/10.1073/...

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Abdulmunaim Eid @ameid.bsky.social · 06/01/2025

Arabic influenced French & English as well, but similar words may not be obvious to speakers of these languages incl. Arabs. The Paradise Dictionary معجم الفردوس discusses English words of Arabic origin; it lists thousands of words & traces their etymology–often Arabic -> French -> English.

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Abdulmunaim Eid @ameid.bsky.social · 27/12/2024

Our chapter 'Therapeutic Strategies in Neurodegenerative Diseases' in 'Neuroimmune Pharmacology and Therapeutics' is now published. It highlights gene therapy, cell therapy and immunotherapy as key strategies under investigation and summarizes clinically available therapies. Link: rdcu.be/d4YQq

doi.org

Therapeutic Strategies in Neurodegenerative Diseases

Neurodegenerative diseases are characterized by progressive loss of specific populations of neurons giving rise to clinical syndromes of neurological dysfunction. The World Health Organization declare...

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