Alkis Hadjiosif @alkismh.bsky.social · 03/10/2026One of the very unfortunate consequences of AI is that it rendered dashes—one of my favorite means of punctuation—suspicious 140
Reposted by Alkis Hadjiosifallen institute @alleninstitute.org · 01/04/2026The Orange Cat Brain Atlas is here. 🧠🐈 Today, we published the first comprehensive cellular map of the orange cat brain. The new atlas reveals a single, specialized neuron responsible for behaviors like staring at walls, knocking objects off tables, and the 3am "zoomies." 10379127
Alkis Hadjiosif @alkismh.bsky.social · 08/01/2026This moves the goalposts for what makes a mind-blowing illusion 010
Reposted by Alkis HadjiosifGavin Buckingham @drgbuckingham.bsky.social · 08/01/2026Leftmost goal isn't actually facing the camera 5375
Alkis Hadjiosif @alkismh.bsky.social · 06/01/2026Great for MOCAP making it to last Saturday's NYT Crossword 000
Alkis Hadjiosif @alkismh.bsky.social · 12/12/2025Reach out if you have any comments! I will put together a bluesky version ("skeetprint"?) over the weekend. 010
Alkis Hadjiosif @alkismh.bsky.social · 12/12/2025I want to thank to the reviewers for their tough but fair feedback, which I honestly think made this work stronger. I was nervous about trying eLife's new model, but editor and reviewers made it a smooth experience. (Also: the longest revision/response letter I have written so far). 110
Alkis Hadjiosif @alkismh.bsky.social · 12/12/2025Our latest work is now a version-of-record article (rather than a reviewed preprint) at @elife.bsky.social : elifesciences.org/articles/90780 with co-authors Kahori Kita, Scott Albert, Bob Scheidt, @rezashadmehr.bsky.social, and John Krakauer.elifesciences.orgSeparating the control of moving and holding in human post-stroke arm paresisPatients with stroke often show impairment in both moving and holding the arm, deficits that are dissociable experimentally, suggesting that moving and holding are controlled by separate neural mechan... 171
Alkis Hadjiosif @alkismh.bsky.social · 05/12/2025Random thoughts while going through paper proofs - how long until the terms "clockwise" and "counterclockwise" stop making intuitive sense? As traditional clocks become less common/relevant 110
Alkis Hadjiosif @alkismh.bsky.social · 30/11/2025Trust as in, is the linear fit shown indeed calculated based on the data? Maybe, there are many blue dots on the top-right. More color contrast would be nice! Trust as in, is a linear fit a good description of what's going on here, not so sure... 010
Alkis Hadjiosif @alkismh.bsky.social · 13/11/2025The frequency of review requests seems to follow the "when it rains, it pours" rule 010
Reposted by Alkis HadjiosifGavin Buckingham @drgbuckingham.bsky.social · 25/10/2025For your enjoyment (by @jagarikin) 513540
Alkis Hadjiosif @alkismh.bsky.social · 16/07/2025Non-science post: if you are among the trivia aficionados in LearnedLeague, check out today's round on Ancient Roman cuisine that my friend Max and I put together! 000
Reposted by Alkis HadjiosifASNR @asnrehab.bsky.social · 27/06/2025Recently published work found that reinforcement motor learning was impaired in individuals within 3 months after #stroke. The findings are important for optimizing #neurorehabilitation after stroke as some #rehabilitation approaches rely on reinforcement. 🧠📈 🧪 journals.sagepub.com/doi/abs/10.1...journals.sagepub.comReinforcement Learning is Impaired in the Sub-acute Post-stroke Period - Meret Branscheidt, Alkis M. Hadjiosif, Manuel A. Anaya, Jennifer Keller, Mario Widmer, Keith D. Runnalls, Andreas R. Luft, Amy ...Background: In humans, most spontaneous recovery from motor impairment after stroke occurs in the first 3 months. Studies in animal models show higher responsiv... 063
Alkis Hadjiosif @alkismh.bsky.social · 22/05/2025I am also honored to receive a Career Development Award from the @americanheart.bsky.social to push this work forward. I want to thank both the AHA and my faculty mentors in this award: David Lin at MGH, Conor Walsh at Harvard SEAS, and Monica Perez at Shirley Ryan. 071
Alkis Hadjiosif @alkismh.bsky.social · 22/05/2025Excited to share my recent appointment as Instructor at MGH/HMS! I will continue and expand my work dissecting the neural mechanisms behind the different components of post-stroke motor impairment. The goal/hope is that better mechanistic understanding will reveal new targets for rehabilitation. 060
Alkis Hadjiosif @alkismh.bsky.social · 15/05/2025Correct, all mysteries in the brain will be unveiled through the *cough* prism of visuomotor rotations. 010
Alkis Hadjiosif @alkismh.bsky.social · 11/05/2025This suggests a clear benefit for latency reduction in computer-based training that involves implicit sensorimotor learning. Critically, it means that across-study differences may be explained by differences in unmeasured feedback latencies. We thus need to measure, report, and minimize latency. 6/6 010
Alkis Hadjiosif @alkismh.bsky.social · 11/05/2025We found that, just a 60 ms increase in latency (from 25 ms to 85 ms) decreased implicit learning by 1/3 and increased explicit learning proportionally. Implicit sensorimotor learning was much more (5-10x) sensitive to latencies in the sub- 100 ms range than to higher latencies. 5/6 110
Alkis Hadjiosif @alkismh.bsky.social · 11/05/2025We trained participants on a visuomotor rotation (VMR) under latencies of 25, 85, or 300ms. 25ms was the minimum we could achieve in our optimized setup; 85ms is within the latencies expected on an average setup. We dissected learning into implicit and explicit components using aim reports. 4/6 100
Alkis Hadjiosif @alkismh.bsky.social · 11/05/2025Neurophysiology suggests that learning-related mechanisms such as cerebellar LTD and cortical LTP are disrupted by similarly short latencies, so this question might be worth investigating. 3/6 100
Alkis Hadjiosif @alkismh.bsky.social · 11/05/2025Short delays in visual feedback (under 100 ms) are common in human-computer interactions—and, while hard to perceive, they’re known to hurt performance in tasks like pointing or robotic surgery. Do these tiny lags also impair sensorimotor learning? 2/6 100
Alkis Hadjiosif @alkismh.bsky.social · 11/05/2025Our latest paper with Maurice Smith and team is now out: Tiny visual latencies can profoundly impair implicit sensorimotor learning, in Scientific Reports rdcu.be/eldlh. A brief summary: 1/nrdcu.beTiny visual latencies can profoundly impair implicit sensorimotor learningScientific Reports - Tiny visual latencies can profoundly impair implicit sensorimotor learning 193
Alkis Hadjiosif @alkismh.bsky.social · 02/12/2024I had a similar experience - it was a schematic based on a photo, where you could arguably recognize the participant (one of the authors on the paper!) I guess biorxiv doesn't want to deal with permissions etc. so the simplest thing to do is avoid human photography altogether. 010
Alkis Hadjiosif @alkismh.bsky.social · 23/11/2024My take/intuition is that, talking to a human (or at least being convinced that you are) matters by itself. The exact same responses won't be as effective if one suspects the therapist is an LLM 010
Alkis Hadjiosif @alkismh.bsky.social · 18/11/2024Thanks for putting this together! I'd like to be added. 010
Alkis Hadjiosif @alkismh.bsky.social · 08/11/2024Hello, world! I'm happy to join the neuro community here at bluesky. I look forward to engaging discussions. 0100