iiinova — where your digital self keeps evolving

Soragni:Lab @alice.soragnilab.com · 05/07/2026

Happy Fourth of July. A reminder that democracy, like science, depends on care, integrity, and collective responsibility. Let us all do our part

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Soragni:Lab @alice.soragnilab.com · 20/04/2026

Truer words were never spoken. Really important session on cancer prevention and screening with a focus on policies #AACR26

Title slide from Dr. Philip Castle reading “the best cancer is the cancer that never happens”

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Soragni:Lab @alice.soragnilab.com · 19/04/2026

First AACR Meeting ever as a non-UCLA affiliate, big changes and so excited for what’s ahead. If you see me around, stop to say hi 👋 #AACR 26

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Soragni:Lab @alice.soragnilab.com · 31/03/2026

Cancer research, dismantled. Only *35* grants awarded so far in FY26. NCI stats for new and competitive grant renewals from: grant-witness.us/funding_curv...

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Soragni:Lab @alice.soragnilab.com · 30/01/2026

Last day at UCLA, fourteen years in the making. Very excited for what is ahead. Huge kudos to my team and our fantastic collaborators, they keep me going.

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Soragni:Lab @alice.soragnilab.com · 31/10/2025

Contributed to this piece in Cancer Discovery on the new NIH organoid effort. Amid all uncertainty, good to see real commitment to human models and standards. Organoids are central to how we study disease and test therapies- it is about time the system reflects it 🔗 aacrjournals.org/cdnews/news/...

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Soragni:Lab @alice.soragnilab.com · 26/08/2025

This study builds on our unpassaged (or passage zero) paradigm yet extends it to include not only short term (6 days) cultures, but also long term (one month) and short term cultures grown in hypoxia.

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Soragni:Lab @alice.soragnilab.com · 28/05/2025

I have not been around much over the past month, so let's talk what I have been up to... mostly travel! And yes, despite everything else swirling around, science, when it’s sharp, generous, and moving forward, is still unmatched joy 🧵

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Soragni:Lab @alice.soragnilab.com · 11/05/2025

Spent about 20 hours in Rome visiting the Pediatric Hospital Bambino Gesù, engaging with Dr. Locatelli and his terrific team on rare sarcoma therapies. Amazing science, outstanding food and, well, Rome is always worth spending a little time in, no matter how tired or jet-lagged..

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Soragni:Lab @alice.soragnilab.com · 28/04/2025

While I am so very sad to be missing this year's AACR Annual Meeting in Chicago, we have a fantastic contingent representing the lab! #AACR25 /n

List of Soragni Lab Posters presented at #AACR25

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Soragni:Lab @alice.soragnilab.com · 11/04/2025

Has been tough folks, at many levels, no two ways about it. But the science has been so fantastic - some great progress in lab, exciting papers coming along, awesome new discoveries and novel platforms, fantastic meetings that brought about new and exciting collaborations.

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Soragni:Lab @alice.soragnilab.com · 16/03/2025

Things are tough all around, don't get me wrong. Yet, I just spent the better part of a week in Boston focused on precision medicine #AACRprecmed25 and feel so recharged. The ongoing research holds such incredible promise for both rare and common cancers. If only the grip on the NIH would loosen..

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Soragni:Lab @alice.soragnilab.com · 13/03/2025

Now @michaelhoffman.bsky.social starting his talk on inferring transcription factor binding from different data modalities. Loved the reference to Cunningham’s law #AACRprecmed25

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Soragni:Lab @alice.soragnilab.com · 12/03/2025

Such an interesting talk from Dr. Eisfeld. These inclusive studies highlight critical genomic differences that may eventually impact care and are so so important - we need more of these and bigger cohorts, not fewer. #AACRPM25

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Soragni:Lab @alice.soragnilab.com · 11/03/2025

This first AACR meeting on functional and genomic precision medicine has officially started! Dr. Mardis gave the introductory remarks followed by our first plenary speaker, Dr. Flaherty, who will focus on the collision of genomic and functional precision medicine #AACRPM25

Elaine Mardis giving introductory remarks

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Soragni:Lab @alice.soragnilab.com · 28/02/2025

Waiting for those 50 study sections to show up on the Federal Register www.federalregister.gov/documents/se...

waiting man meme from narcos. Man shown sadly waiting in 3 poses.

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Soragni:Lab @alice.soragnilab.com · 25/02/2025

Every session listed as starting on 02/25 has a * which indicates "* Denotes this meeting did not take place as scheduled". Also, none of them is on the Federal Register thus they literally cannot take place.

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Soragni:Lab @alice.soragnilab.com · 21/02/2025

but also. hope @sbarolo.bsky.social appreciates some of my efforts 😆

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Soragni:Lab @alice.soragnilab.com · 19/02/2025

Trying to get a badge 10 minutes after registration closure (LA traffic for you..) and got asked three times if I am at the right conference. Person at the desk was not convinced that I am chairing a session shortly 😂 Am I at the right conference?? lol

Handwritten conference badge for the BPS meeting in LA

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Soragni:Lab @alice.soragnilab.com · 08/01/2025

For context, we are now surrounded by 4 poorly/not controlled wildfires. The air is heavy, the situation unprecedented and the destruction unimaginable in Los Angeles. We are all one global warming-fueled disaster away from becoming climate refugees.

Map from Watchduty showing the areas affected by 4 wildfires currently ongoing in the Los Angeles area.

Air quality map showing very poor air quality in Los Angeles due to the ongoing fires

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Soragni:Lab @alice.soragnilab.com · 29/11/2024

Post a photo of yourself from a different era.. This was likely taken at the start of my master at the University of Bologna

A group of students most in white labcoats taking a class picture in a lab. I have bangs because bangs were actually a thing at the time, I promise.

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Soragni:Lab @alice.soragnilab.com · 20/11/2024

I need a version of the serenity prayer but for daycare rules. On a related note, I gained one very messy but plenty cute office mate for the day.

My toddler sitting at my office desk, drawing usnig a pink marker

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Soragni:Lab @alice.soragnilab.com · 16/11/2024

Speaking of importing timelines, here's an oldie but goodie: a view of a patient-derived tumor organoid leveraging some of the new methods we are developing. Something amazing they are, organoids.

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Soragni:Lab @alice.soragnilab.com · 14/11/2024

Quite the Downtown Los Angeles sunrise as I head over to CTOS for one glorious day #CTOS24 #sarcoma

Downtown LA at sunrise, just a street, couple traffic lights and the sun waking up

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Soragni:Lab @alice.soragnilab.com · 14/11/2024

Would love to add you but I am not sure why it keeps telling me that your handle does not exist?? I have not seen this before, can try again later

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Soragni:Lab @alice.soragnilab.com · 11/11/2024

Just back from a really awesome Forbeck meeting on fusion oncogenes in Denver. Lots of science, even more snow.. I really loved the white board + handful of slides (if any) format, which led to some really great discussions

Pic of a white landscape covered in snow - of course the biggest november snow storm in years happens over the 3 days I am in Denver..

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Soragni:Lab @alice.soragnilab.com · 19/09/2024

When you know you are buying too much from a single vendor

Email from vendor addresses me as "Dear VIP Member" and expresses gratitude for my "support" lol

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Soragni:Lab @alice.soragnilab.com · 19/09/2024

Bluesky has over 10Mio users, time to share some science! We have a new preprint out investigating how mutant p53 misfolding and aggregation relates to tumor progression. We focus on HGSOC, driven by mutant p53. But is p53 mutation sufficient for malignant transformation..? 🧪 shorturl.at/h6ac6

Schematics showing timing of progression to ovarian cancer and how that is synced with p53 mutation, misfolding and aggregation as we describe in the paper

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Soragni:Lab @alice.soragnilab.com · 17/09/2024

Hey, not too shabby, I am one of the early 0.5%

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Soragni:Lab @alice.soragnilab.com · 11/09/2024

Guess who has two thumbs and just got *another* #notthecover

grumpy cat unumused by having another great cover concept killed by the journal

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Soragni:Lab @alice.soragnilab.com · 06/05/2024

There was a project I grew attached to, that involved people I came to like very much, and bursted despite my unrelentess hope it would materialize. Quite sad about this one. I do enjoy the irony of these fortune cookies today though

Two fortune cookies that appeared today. First says: "have a clear sense of your priorities" and the second says: "success is within reach, allow yourself time"

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Soragni:Lab @alice.soragnilab.com · 09/02/2024

It's happening... oh it's happening....

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Soragni:Lab @alice.soragnilab.com · 28/11/2023

My phone showing me this as pic of the day just feels mean tbh

Pic of the Gyeongbokgung Palace in Seoul, that I visited just over a week ago and yes, I rather be there for another week or 2 honestly

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Soragni:Lab @alice.soragnilab.com · 26/11/2023

..it's beginning to look a lot like Christmas.. ♬ 🎄 🧑‍🎄

New biosafety hoods getting installed in lab

Boxes containing sparkly new microscope!

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Soragni:Lab @alice.soragnilab.com · 16/11/2023

The 2023 AACR-KCA meeting has started, looking forward to some very exciting precision medicine in cancer science on the background of the beautiful city of Seoul #AACRKCA23

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Soragni:Lab @alice.soragnilab.com · 03/11/2023

When the sample ends up in formalin instead than in the fridge

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Soragni:Lab @alice.soragnilab.com · 01/11/2023

You can't be rejected if you don't send in an application

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Soragni:Lab @alice.soragnilab.com · 22/10/2023

We are hiring!! We are looking for a Postdoc to develop a Cell Painting assay in patient-derived organoids for rare diseases. If you recently graduated and have an interest in assay technology, preclinical modeling, drug discovery, and personalized medicine, get in touch. Info below, please share!

Ad for postdoc job at UCLA in the Soragni Lab. To apply send CV, list of 3 refs and cover letter to: sswearingen@mednet.ucla.edu

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