iiinova — where your digital self keeps evolving

Alex Weuthen @alexweuthen.bsky.social · 05/06/2026

#PuG2026 crowd: Are you interested in task-EEG/fMRI+psychopharmacology? join our symposium tomorrow at 9:00 AM in HS15, where we address neurotransmitter, neuropeptide and hormonal system involvement in cognition, affect and perception. @jtegelbeckers.bsky.social

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Alex Weuthen @alexweuthen.bsky.social · 05/06/2026

#PuG2026 crowd: Are you interested in brain metabolite & connectivity changes by physical vs. cognitive exertion? Come to my Poster (113) at 10:00 AM, to discuss how we localize working memory-related brain activity and determine regional brain energy metabolism changes using 7T-fMRI & 1H/31P-MRS.

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Reposted by Alex Weuthen

Alfie Wearn @alfiewearn.bsky.social · 10/03/2026

Neuromodulatory neurons are extremely susceptible to stress. I argue that their fragility is an inherent weak point, the breaking of which directly leads to Alzheimer’s Disease. I discuss this idea and its implications in a recently published perspective piece: dx.doi.org/10.1002/alz....

dx.doi.org

The neuromodulatory fragility hypothesis of Alzheimer's disease pathogenesis

Sporadic Alzheimer's disease (AD) is associated with numerous risk factors, yet its precise cause remains unclear. Here, we describe a novel framework for AD pathogenesis, whereby diverse risk factor...

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Reposted by Alex Weuthen

Panagiotis Iliopoulos @piliopoulos.bsky.social · 16/03/2026

Our paper is out in @commsbio.nature.com! 🧵 We found that hippocampal-prefrontal connectivity acts as a "neural resource" — it predicts both memory performance AND training-related improvement. More info below 👇

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Reposted by Alex Weuthen

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 11/02/2026

Convergent molecular signatures of ageing and injury in the peripheral nervous system www.biorxiv.org/content/10.64898/20…

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Reposted by Alex Weuthen

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 05/12/2025

Grey matter embedding of the cholinergic system www.biorxiv.org/content/10.64898/20…

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Reposted by Alex Weuthen

Hans Kirschner @hanskirschner.bsky.social · 29/07/2025

📣 Final version of our @elife.bsky.social article is now online! We show that in individuals with moderately low baseline performance, methamphetamine reduces the tendency to misinterpret high outcome noise. 🥳 elifesciences.org/articles/101...

elifesciences.org

Methamphetamine-induced adaptation of learning rate dynamics depend on baseline performance

In individuals with moderately low baseline performance, methamphetamine reduces the tendency to misinterpret high outcome noise.

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Reposted by Alex Weuthen

Sidhant Chopra @sidchop.bsky.social · 05/06/2025

Check out our latest open data release. n=240, most with a dsm-5 dx with extensive phenotying (~100 scales/subscale), rest and task functional imaging. See @carrisacocuzza.bsky.social's thread below for deets and links 👇🏾👇🏾👇🏾

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Reposted by Alex Weuthen

Sidhant Chopra @sidchop.bsky.social · 12/05/2025

🧠💊New preprint differentiating antipsychotic medication vs. illness effects on cortical thickness in people w/ psychosis. Finding: People receiving placebo show prominent cortical thinning over 1st year of illness, whereas those receiving antipsychotics do not. 1/3 www.medrxiv.org/content/10.1...

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Alex Weuthen @alexweuthen.bsky.social · 05/02/2025

Learning an association does not always succeed on the first attempt. What are the brain mechanisms underlying adaptations in memory formation on following learning attempts? We addressed this question by quantifying single-trial fMRI stimulus processing evidence: www.nature.com/articles/s44...

nature.com

Error-driven upregulation of memory representations - Communications Psychology

Using single-trial analysis in fMRI, this study shows that activity in brain areas associated with error monitoring and cognitive control differentiates between items that are later remembered correct...

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Reposted by Alex Weuthen

Communications Psychology @commspsychol.nature.com · 31/01/2025

With single-trial analysis, this fMRI study shows that activity in brain areas associated with error monitoring & cognitive control differentiates between items remembered correctly vs those where mistakes persist. @alexweuthen.bsky.social @hanskirschner.bsky.social www.nature.com/articles/s44...

nature.com

Error-driven upregulation of memory representations - Communications Psychology

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