Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of zimisle...

Decision making for the treatment of kidney failure in older adults, should incorporate patient preferences. This discrete choice experiment (DCE) aimed to identify the health outcome preferences of o...

Thirst and salt appetite are critical for maintaining fluid balance. In this review, Grove and Knight discuss how fluid imbalances are sensed at a molecular level and how these signals converge on bra...

As her father awaits an organ for his third transplantation, a surgical resident retrieves a kidney from a fellow hockey fan, recognizing at a deep, personal level the value of his gift of life.

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The need to suppress a patient’s immune system after the transplantation of allogeneic cells is associated with wide-ranging side effects. We report the outcomes of transplantation of genetically m...

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A Swiss film about a nurse pushed to her limits one night is being praised for the picture it paints of treacherously underfunded healthcare. The director talks about the ‘heart-pounding’ story that i...

Gaza: ‘Clean it out then bring in something good’ ► https://youtu.be/43oZ0yUDG8E “No one knows what will come to replace the international system that is cur...

This Viewpoint explores the possible negative effects of the End Kidney Deaths Act on organ donation and transplant and offers strategies on how to narrow the gap between organ demand and supply.

De novo donor-specific HLA-DQ antibodies detected by single antigen beads (SAB) are significantly associated with chronic antibody-mediated rejection …

This article examines the economic value of transplant nephrologists and the need for adequate compensation. Kidney transplantation is a health and li…

tion with transplant outcomes. Being prefrail significantly impacts both graft and patient survival, often beginning with just 1 Fried criterion. Rather than viewing frailty as a categorical state, it...

This cohort study evaluates the risk for acute kidney injury and other adverse effects from as-needed and 1-time blood pressure medications in hospitalized veterans.

Where should society draw the line on extreme wealth? A fresh account sets out the logic and suggests how to redress inequality.

Human rights organizations and residents describe the situation in the enclave as getting more desperate. Here is a closer look.

This cohort study aims to determine whether patient to nurse or patient to social worker staff ratios are associated with access to kidney transplant for adolescents and young adults.

bisphosphonates associates with lower incidence of non-vertebral fractures after kidney transplantation. Methods: We conducted a retrospective review for all Southern California Kaiser Permanente k...

BACKGROUND: Remote ischemic preconditioning (RIPC) has 2 time windows for organ protection: acute and delayed. Previous studies have mainly focused on the organoprotective effects of acute RIPC. We ai...

This cohort study evaluates whether glucagon-like peptide receptor agonists (GLP-1RAs) are associated with risk of obesity-associated cancer among patients with type 2 diabetes compared with insulin o...

This systematic review and individual patient data meta-analysis investigates the association of an alternative low-density lipoprotein (LDL) strategy with differences in long-term efficacy and safety...

Bloodstream infections are associated with substantial morbidity and mortality. Early, appropriate antibiotic therapy is important, but the duration of treatment is uncertain. In a multicenter, non...

This systematic review and meta-analysis evaluates the association of sodium correction rates with mortality among hospitalized adults with severe hyponatremia.