Irritable bowel syndrome (IBS) management guidelines recommend that behavioural therapies, particularly brain–gut behaviour therapies, should be consi…

Several behavioural therapies are efficacious for global symptoms in IBS, although the most evidence exists for those classed as brain–gut behaviour therapies. However, certainty in the evidence for a...

Biases observed in gastroenterologists toward patients with IBS originate as early as the beginning of medical school, including seeing IBS as a "less real" disease and more difficult to treat. Earlier educational interventions may be helpful in identifying and addressing these biases.

A network meta-analysis of 28 trials evaluating dietary interventions for IBS found that reducing starch and sucrose ranked first in improving global symptoms.

Nature Reviews Gastroenterology & Hepatology, Published online: 25 April 2025; doi:10.1038/s41575-025-01065-9This Perspective discusses misconceptions and controversies in the clinical management of irritable bowel syndrome (IBS), including diagnosis, testing and treatment, among others. Areas in which issues have been resolved and those that require further research and clarification are highlighted.

Hypnotherapy and CBT show moderate certainty for treatment efficacy with clinically relevant effect sizes. No conclusions can be made about the other therapies and treatment success due to very low ev...

April marks Irritable Bowel Syndrome (IBS) Awareness Month, and April 19 World IBS Day, together aiming to raise awareness of this debilitating condition. Characterised by abdominal pain and a change ...

In terms of dietary interventions for IBS, the most evidence exists for a low FODMAP diet, but other promising therapies are emerging and should be the subject of further study.

Some gut–brain neuromodulators are efficacious in reducing global symptoms and abdominal pain in IBS. The findings support guidelines that recommend use of tricyclic antidepressants for ongoing global...

Some gut–brain neuromodulators are efficacious in reducing global symptoms and abdominal pain in IBS. The findings support guidelines that recommend use of tricyclic antidepressants for ongoing global...

Some gut–brain neuromodulators are efficacious in reducing global symptoms and abdominal pain in IBS. The findings support guidelines that recommend use of tricyclic antidepressants for ongoing global...

In terms of dietary interventions for IBS, the most evidence exists for a low FODMAP diet, but other promising therapies are emerging and should be the subject of further study.

Background Low-dose amitriptyline, a tricyclic antidepressant (TCA), was superior to placebo for irritable bowel syndrome (IBS) in the AmitripTyline at Low-dose ANd Titrated for Irritable bowel syndro...

Podcast Episode · Two guys talking **it - A Gastroenterology and Hepatology podcast · 22/01/2025 · 1h 11m