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alex-bronstein.bsky.social

@alex-bronstein.bsky.social

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Reposted by @alex-bronstein.bsky.social

Nature Biotechnology @natbiotech.nature.com · 29/06/2026

Experiment-guided AlphaFold3 resolves measurement-consistent protein ensembles - @istaresearch.bsky.social @alex-bronstein.bsky.social @paulschanda.bsky.social @sankethvedula.bsky.social www.nature.com/articles/s41...

Experiment-guided AlphaFold3 resolves measurement-consistent protein ensembles - Nature Biotechnology

A generative model using AlphaFold3 as prior infers protein conformational ensembles consistent with measured experimental data.

Reposted by @alex-bronstein.bsky.social

Institute of Science and Technology Austria (ISTA) @istaresearch.bsky.social · 29/06/2026

First author, ISTA PhD student Advaith Maddipatla. Co-leading authors: @alex-bronstein.bsky.social, Ailie Marx, @paulschanda.bsky.social, and @sankethvedula.bsky.social.

ISTA researchers guide AlphaFold with experimental data, paving the way for improved future predictive models. Left to right: Advaith Maddipatla, Meital Bojan, Alex Bronstein, Nadav Sellam Bojan, and Paul Schanda. © ISTA