The increasing prevalence of Enterococcus faecium (EF) bloodstream infections (BSIs) over the last years is concerning due to its high mortality rates and its intrinsic resistance to many antibiotics,...

PBPs are more than static β lactam targets. Host conditions rewire PBP activity and peptidoglycan architecture, shaping tolerance, resistance, and how we design salvage regimens.

Alberto Enrico Maraolo, Giancarlo Ceccarelli; It is time to go beyond the association between colistin and meropenem for invasive carbapenem-resistant Acin

Don’t know much about geography? Decision support for the evaluation of patients with suspected high consequence infectious diseases - Volume 5 Issue 1

AbstractObjectives. Cefixime is a promising oral treatment alternative for early syphilis but only very limited efficacy data exist. We evaluated the effic

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Infection - Meropenem/vaborbactam (M/V) and ceftazidime/avibactam (C/A) are considered key agents in treating KPC-producing Klebsiella pneumoniae (Kp) infections. We compared these two drugs in...

Background and Objective Acyclovir is a primary treatment for central nervous system (CNS) infections caused by herpes simplex virus (HSV) and varicella-zoster virus (VZV). However, patient outcomes r...

In this article on measles, the authors review the epidemiology, clinical presentation, and associated illnesses as well as treatment and prevention strategies.

Bloodstream infections (BSIs) caused by Staphylococcus aureus are common worldwide, representing one of the most relevant issues in clinical infectious diseases practice. In particular, BSIs by met...

In this Review, Male and Jones provide an overview of the current vaccines that are offered during pregnancy and to newborns, explaining the rationale behind the different vaccination programmes and t...

Quick Take Video Summary from The New England Journal of Medicine — Placebo-Controlled Trial of Tecovirimat for Endemic Mpox

Despite major advances in artificial intelligence (AI) research for healthcare, the deployment and adoption of AI technologies remain limited in clinical practice. This paper describes the FUTURE-AI f...

### What you need to know Fever of unknown origin (also known as fever of undetermined origin or pyrexia of unknown origin) is often a debilitating clinical syndrome. Patients with this syndrome pres...

Koch et al. model scenarios of emergence of a single pan-resistant Escherichia coli strain in the United States. Findings suggest dire mortality outcomes and highlight the importance of measures to pr...

Data from randomized trials evaluating the effectiveness of tuberculosis (TB) preventive treatment for contacts of multidrug-resistant (MDR)-TB are lacking. Two recently published randomized trials...

A regimen consisting of 2 days of intraurethral LBP-EC01 and 3 days of concurrent intravenous LBP-EC01 (1 × 1010 PFU) and oral TMP–SMX twice a day was well tolerated, with consistent pharmacokinetic profiles in urine and blood. LBP-EC01 and TMP–SMX dosing resulted in a rapid and durable reduction of E coli, with corresponding elimination of clinical symptoms in evaluable patients. LBP-EC01 holds promise in providing an alternative therapy for uncomplicated UTIs, with further testing of the group A dosing regimen planned in the controlled, double-blind, second part of ELIMINATE.

Collaborations between ophthalmologists and infectious disease specialists are critical for optimizing care of many patients with eye infections. We review

—- GLOBAL INFECTIONPREVENTION AND MANAGEMENT INHEALTHCARE ISBN: 978-88-943799-3-8FIRST PUBLISHED on 18 November 2024 — Volume 1 Antimicrobial resistance and One Health VOLUME 1download …