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William F Wright

@wwrighid.bsky.social
1.5K followers 80 following 160 posts

Fellow Infectious Diseases Society of America (FIDSA); ABIM Infectious Diseases; ABP Clinical Microbiologist (Yale); MPH Biostatistics and Epidemiology; Clinical Researcher

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William F Wright @wwrighid.bsky.social · 28/04/2026
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social 🚨 Among patients vaccinated with PCV21, have you observed invasive Pneumococcal serotype 4 infections; particularly in the Eastern US? A. Yes B. No C. Other strains
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William F Wright @wwrighid.bsky.social · 08/03/2026
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social 🚨 Humbled by the opportunity to contribute to Clinical Infectious Diseases with this State of the Art Review with a fantastic group of experts!
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William F Wright @wwrighid.bsky.social · 01/01/2026
Fantastic work BK!
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William F Wright @wwrighid.bsky.social · 19/12/2025
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social 🚨 POLL: For patients with conditions such as DM, CKD, and/or chronic liver disease needing Rabies PEP do you give the day 28 (ie., 5-doses) dose or stop at day 14 (ie., 4-doses)?
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William F Wright @wwrighid.bsky.social · 28/10/2025
@obliviousfool.bsky.social @themeparkdiet.bsky.social Disney fans take a guess where we got this very tasty mummy Mickey Mouse treat!
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JAC-AMR @jac-amr.bsky.social · 25/09/2025
Eravacycline: a further weapon against NDM-producing Klebsiella pneumoniae? The case of a man with surgical site infection successfully treated with eravacycline plus ceftazidime/avibactam plus aztreonam doi.org/10.1093/jaca... #JACAMRNews #IDSky #AMRrounds @wwrighid.bsky.social
Antibiogram showing the resistance profiles of the wound isolate (panel a) and intra-operative isolate (panel b) of NDM-producing Klebsiella pneumoniae complex according to CLSI and EUCAST interpretations for a range of antimicrobial agents, as described in Galfo et al., AMRrounds: susceptibility to the new tetracycline-derivative eravacycline of New Delhi metallo-β-lactamase-producing Klebsiella pneumoniae complex, JAC-Antimicrobial Resistance, Volume 7, Issue 4, August 2025, dlaf153, https://doi.org/10.1093/jacamr/dlaf153
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William F Wright @wwrighid.bsky.social · 21/09/2025
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social #FUOrounds: This week celebrating the University of Tennessee win and invited to discuss #FUO at the Southern Grit to enjoy collegial friendship and good southern food!
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William F Wright @wwrighid.bsky.social · 07/09/2025
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social Although UK football 🏈 lost to Ol Miss, we are starting the Fall 2025 FUOrounds at Salt and Vinegar in Lexington, Kentucky tonight! DM if you are interested in hosting an event.
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William F Wright @wwrighid.bsky.social · 18/08/2025
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social Humbled today as a patient’s wife who works with Dr Watson (who is yes still living at age 97) brought me a signed copy of his book!
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William F Wright @wwrighid.bsky.social · 07/06/2025
@obliviousfool.bsky.social @themeparkdiet.bsky.social Formerly known as Pizza Planet and inspired by the muppets character Rizzo the Rat, Pizzerizzo in Hollywood Studios is closing operations on June 7, 2025 to make way for the Monsters Inc themed area!
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William F Wright @wwrighid.bsky.social · 07/06/2025
Remember June 6, 1944, D-day 81 years ago! 🇺🇸 youtu.be/159a5NQEFeM
youtu.be
US veterans mark 81 years since D-Day in France
YouTube video by USA TODAY
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Ghost Host @obliviousfool.bsky.social · 28/04/2025
#SpaceshipEarthSunday
Spaceship Earth lit in blue
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ID Chief @ UMich @adamlauring.bsky.social · 23/04/2025
Really excited to be a part of this study and see it published today! Efficacy of Baloxavir Treatment in Preventing Transmission of Influenza | New England Journal of Medicine www.nejm.org/doi/full/10....
nejm.org
Efficacy of Baloxavir Treatment in Preventing Transmission of Influenza | NEJM
Baloxavir marboxil (baloxavir) rapidly reduces influenza virus shedding, which suggests that it may reduce transmission. Studies of treatment with neuraminidase inhibitors have not shown sufficient...
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William F Wright @wwrighid.bsky.social · 03/04/2025
@obliviousfool.bsky.social Are you available to connect by direct message here or offline?
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William F Wright @wwrighid.bsky.social · 21/03/2025
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social 🔥 Ceftriaxone MIC cutoff of 8 μg/ml is an excellent predictor of ESBL production; PPV and NPV approaching 100% and 99.5%, respectively. doi.org/10.1128/JCM.00716-14
doi.org
Determining the Optimal Ceftriaxone MIC for Triggering Extended-Spectrum β-Lactamase Confirmatory Testing | Journal of Clinical Microbiology
ABSTRACT As routine testing of clinical isolates for extended-spectrum β-lactamase (ESBL) production (screen plus phenotypic confirmatory testing) is no longer required by the Clinical and Laboratory ...
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William F Wright @wwrighid.bsky.social · 04/03/2025
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social 🚨 Fever of Unknown Origin (FUO) rounds at Disney Springs with cold brew coffee and special cookies!
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William F Wright @wwrighid.bsky.social · 26/02/2025
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social 🚨 Poll: 1. Is anyone using 3-weeks ABX for residual DFO after I&D? 2. In the study objectives, is anyone concerned with not requiring histology? doi.org/10.1093/cid/ciaa1758
doi.org
Three Weeks Versus Six Weeks of Antibiotic Therapy for Diabetic Foot Osteomyelitis: A Prospective, Randomized, Noninferiority Pilot Trial
In this prospective, randomized pilot trial investigating the duration of postdebridement antibiotic therapy for diabetic foot osteomyelitis, a short durat
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JAC-AMR @jac-amr.bsky.social · 20/02/2025
Successful use of ceftazidime/avibactam for an XDR K. pneumoniae empyema secondary to a pleural-biliary fistula: 🔥 New #AMRrounds article just published 👇 doi.org/10.1093/jacamr/dlaf019 @inyourfaecium.bsky.social @wwrighid.bsky.social #JACAMRNews #IDSky #AntimicrobialResistance
Antibiogram showing the resistance profile of an XDR K. pneumoniae isolate according to CLSI and EUCAST interpretations for a range of antimicrobial agents, as described in Michael Casias, Madison Salam, AMRrounds: presumed mechanisms of resistance in a case of XDR Klebsiella pneumoniae empyema, JAC-Antimicrobial Resistance, Volume 7, Issue 1, February 2025, dlaf019, https://doi.org/10.1093/jacamr/dlaf019
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William F Wright @wwrighid.bsky.social · 20/02/2025
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social 🚨 Which risk factor is not recommended for HIV IM Cabotegravir PreP? A. IVDU B. Insertive anal/vaginal C. Receptive anal/vaginal/neovaginal D. CrCl 30-60 or lower
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William F Wright @wwrighid.bsky.social · 15/02/2025
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social No words needed for this one
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William F Wright @wwrighid.bsky.social · 11/02/2025
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social 🚨 Which of the following has a mite-house mouse life cycle and transmitted to humans to cause an eschar rash? A. R akari B. R parkeri C. R prowazekii D. R rickettsii
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William F Wright @wwrighid.bsky.social · 09/02/2025
#IDSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social @davidvanduin.bsky.social @jac-amr.bsky.social 🚨 #AMRrounds: Citrobacter koseri is intrinsically resistant to amoxicillin/ampicillin by which chromosomal Bla-enzyme? A. AmpC B. CKO C. SHV D. TEM
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William F Wright @wwrighid.bsky.social · 09/02/2025
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social 🚨 Remember with cardiac implantable device infections, survival increases with removal of the device; particularly if the valve is infected! doi: 10.1001/jama.2012.497
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William F Wright @wwrighid.bsky.social · 09/02/2025
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social 🚨 Which microorganism is most likely to be associated with a prosthetic valve endocarditis 15 months in the post-operative period? A. HACEK B. MRSA C. MSSA D. Streptococcus species
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William F Wright @wwrighid.bsky.social · 01/02/2025
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social 🚨 Which solid-organ transplantation is associated with the highest risk of donor Toxoplasmosis in a seronegative recipient? A. Cardiac B. Hepatic C. Pulmonary D. Renal
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William F Wright @wwrighid.bsky.social · 26/01/2025
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social Lift other people up. Don’t be the person who brings other people down. It’s as simple as that.
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William F Wright @wwrighid.bsky.social · 26/01/2025
#IDSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social Which of the following if normal would have the highest negative predictive value (NPV) for the cardiopulmonary phase of Hantavirus Pulmonary Syndrome? A. Hemoglobin B. Liver panel C. Platelet count D. Prothrombin time
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William F Wright @wwrighid.bsky.social · 25/01/2025
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social 🚨 COVID-19 NAAT testing: 1. NAAT recommended over antigen-based tests 2. Interpret Ct values with caution as these are not true quantitative assays
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William F Wright @wwrighid.bsky.social · 25/01/2025
#IDSky #PharmSky #TransplantIDSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social Which of the CMV antiviral resistance mutations would affect Letermovir? A. UL51 B. UL54 C. UL56 D. UL97
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William F Wright @wwrighid.bsky.social · 25/01/2025
#IDSky #MedSky #PharmSky #OrthoSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social 🚨 Remember if your microbiology laboratory is using the BioFire Joint Infection Panel for synovial fluid this panel does not include: 1. S epidermidis 2. C acne
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William F Wright @wwrighid.bsky.social · 25/01/2025
#IDSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social Special Culture media: A. B pertussis - Regan-Lowe or Bordet-Gengou agar B. B pseudomallei - Ashdown’s agar C. F tularensis - BCYE, BHI, or Thayer-Martin D. M pneumoniae -Eaton’s agar
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William F Wright @wwrighid.bsky.social · 25/01/2025
#IDSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social Which of the following would be expected to grow better on buffered charcoal yeast extract (BCYE)? A. B pertussis B. B pseudomallei C. F tularensis D. M pneumoniae
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William F Wright @wwrighid.bsky.social · 21/01/2025
@cfbplayoff.bsky.social #IDSky #PharmSky #MedSky @notredame.bsky.social ☘️ Let’s go Irish and “Win One for the Gipper”! 🏈
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William F Wright @wwrighid.bsky.social · 20/01/2025
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social “Sooner or later all the people of the world will have to discover a way to live together in peace” Martin Luther King Jr Nobel Peace Prize, University of Oslo, 10 December 1964.
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The BMJ @bmj.com · 07/01/2025
Fever of unknown origin is often a debilitating clinical syndrome. This article outlines the current diagnostic defining criteria, causes, and evaluation strategies, including newer diagnostic methods that have emerged over the past 20 years www.bmj.com/content/388/...
Fever of unknown original graphic
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William F Wright @wwrighid.bsky.social · 14/01/2025
#IDSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social @chantalrovers.bsky.social @radboudumc.bsky.social Tremendous honor that @bmj.com would highlight our January 2025 #FeverOfUnknownOrigin clinical update on the front cover!
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William F Wright @wwrighid.bsky.social · 13/01/2025
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social 🚨 According to this publication beta-lactams with the highest seizure potential include: 1) Cefazolin, 2) Cefepime, and 3) PCN-G (Table 1). doi.org/10.3390/microorganisms9071505
doi.org
Beta-Lactams Toxicity in the Intensive Care Unit: An Underestimated Collateral Damage?
Beta-lactams are the most commonly prescribed antimicrobials in intensive care unit (ICU) settings and remain one of the safest antimicrobials prescribed. However, the misdiagnosis of beta-lactam-rela...
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William F Wright @wwrighid.bsky.social · 12/01/2025
#IDSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social How would you manage this blood isolate? A. Liposomal Amphotericin-B (LAMB) B. LAMB plus voriconazole, isavuconazole, or posaconazole C. Voriconazole, Isavuconazole, or posaconazole D. Other
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William F Wright @wwrighid.bsky.social · 08/01/2025
#IDSky #PharmSky @cidjournal.bsky.social 🚨 Remember with LTBI Rx, “Ritabutin has fewer or less pronounced drug interactions and may be used in place of rifampin when rifampin is contraindicated due to drug-drug interactions and isoniazid cannot be used (MMWR Recomm Rep 2020;69(No. RR-1):1–11)
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William F Wright @wwrighid.bsky.social · 06/01/2025
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social 🚨 In this #BMJ article we update the clinical practice approach to adult fever of unknown origin #FUO! bmj.com/cgi/content/...
bmj.com
Fever of unknown origin
### What you need to know Fever of unknown origin (also known as fever of undetermined origin or pyrexia of unknown origin) is often a debilitating clinical syndrome. Patients with this syndrome pres...
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William F Wright @wwrighid.bsky.social · 01/01/2025
#IDSky Happy New Year Infectious Diseases colleagues! The @idsainfo.bsky.social worked hard to advocate for the add-on billing code G0545 that can now be used when evaluating inpatient confirmed or suspected infections!
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William F Wright @wwrighid.bsky.social · 31/12/2024
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social #NCAABowlGames 🏈 Go Irish ☘️ #NotreDame
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William F Wright @wwrighid.bsky.social · 30/12/2024
#IDsky #MedSky #PharmSky #disneyparks #disSKY Unfortunately, if visiting #waltdisneyworld there are no #MaryPoppins meet-and-greets at this time and the once planned #MaryPoppins ride has been indefinitely postponed. She will still appear at times in #MagicKingdom and #EPCOT.
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William F Wright @wwrighid.bsky.social · 19/12/2024
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social 🎄 Exciting week of inpatient infectious diseases consults at #JohnsHopkinsMedicine prior to the holidays! Happy holidays everyone!
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Joseph Sassine @josephsassinemd.bsky.social · 15/12/2024
Recently spoke with Health IT News about the results of our innovative trial of remote therapeutic monitoring in OPAT, how RTM helped us reduce infection-related readmissions and improve patient adherence to IV ABx #IDSky #OPAT @ou.edu www.healthcareitnews.com/news/remote-...
healthcareitnews.com
Remote therapeutic monitoring reduces readmissions, academic research shows
The University of Oklahoma College of Medicine did a controlled test and showed the odds of infection-related readmissions were decreased in the RTM group by 76% at 30 days, 80% at 60 days and 68% at ...
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William F Wright @wwrighid.bsky.social · 15/12/2024
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social 🚨 The annual Army vs Navy game is one of America's oldest college rivalries; a moving tribute to service and country for so many! youtu.be/rRMRuXviYEE
youtu.be
2024 Army Navy Football Classic-Gala
YouTube video by West Point - The U.S. Military Academy
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William F Wright @wwrighid.bsky.social · 14/12/2024
#IDSky #AMR #PharmSky @idsainfo.bsky.social 🚨 On December 13, 2024, ASM and IDSA announced partnership to an annual conference on antimicrobial resistance starting in 2026! Cesar Arias, M.D., Ph.D., M.S., and Greg Moeck, Ph.D., are Co-Chairs of the Program Committee. asm.org/Press-Releas...
asm.org
ASM and IDSA to Launch New Conference on AMR
ASM and IDSA partner to create an annual AMR conference to explore the latest advances in antimicrobial drug discovery and development, mechanisms of resistance, pharmacological aspects and more.
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William F Wright @wwrighid.bsky.social · 14/12/2024
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social 🚨 On December 9, 2024, 77 Nobel laureates signed a letter 👇urging the Senate to oppose the confirmation of Robert F. Kennedy Jr. to lead the Department of Health and Human Services.
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Joseph Marcus @josephmarcusid.medsky.social · 13/12/2024
Largest school-based outbreak of neurocysticercosis reported in Belgium 🇧🇪 ✅3 symptomatic children ✅Neg testing in all food handlers ✅All students offered MRI, to find total of 8 cases Source: likely a student #IDSky www.thelancet.com/journals/lan...
thelancet.com
Neurocysticercosis school outbreak in Belgium
Human cysticercosis results from ingesting microscopic Taenia solium eggs shed by a tapeworm carrier, forming cystic larvae (ie, cysticerci) in tissues. These larvae normally encyst in the pig, the natural intermediate host. Upon consumption by humans, they develop into a new intestinal tapeworm. Affecting the human brain, neurocysticercosis is responsible for a third of epilepsy cases in endemic tropical and subtropical regions.1,2
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Mark Hamill @markhamillofficial.bsky.social · 12/12/2024
Posted this at the old place, but thought folks on @bsky.app might like to know I finally met my "mother".
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