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Nature - Vaccination elicits HIV broadly neutralizing antibodies in primates

LJI scientists lead pandemic preparedness as they develop strategies for stopping rodent-borne viruses

LJI researchers discover that 'cross-reactive' T cells can recognize measles and the highly lethal Nipah virus

Simultaneous immunization with three germline-targeting immunogens primes multiple bnAb lineages in NHPs, advancing multiepitope HIV vaccine strategies.

Researchers have developed a research pipeline utilizing bioinformatics and artificial intelligence to fuel the development of “universal vaccines.” These vaccines would address broad viral families a...

A new vaccine design pipeline could protect against emerging SARS-CoV-2 variants and pinpoint conserved T-cell epitopes across respiratory viruses.

New vaccine design pipeline could protect against emerging SARS-CoV-2 variants and more

The COVID-19 pandemic highlighted the critical need for vaccine strategies capable of addressing emerging viral threats. Betacoronaviruses, including …

As Chikungunya spreads into new regions, LJI scientists share a first look at how human T cells target the virus. Their findings may shed light on how viruses can trigger chronic disease.

LJI scientists study cockroach allergies to discover how allergy immunotherapies really work

An HIV envelope trimer mRNA vaccine enables membrane-bound expression and produces a functional immunogen in preclinical mammalian models.

B cells that give rise to neutralizing antibody responses can be extremely rare in the naive B cell repertoire. Madden et al. show that delivery strategy and adjuvant selection affect the recruitment ...

In the midst of pandemic upheaval, researchers have gained fundamental insights about how the body fends off infections.

The SARS-CoV-2 pandemic has highlighted the need for society, as a whole, to be prepared against potential pandemics caused by a variety of different viral families of concern. Here, we describe a roa...

As the so-called bird flu wreaks havoc on chicken and dairy farms, scientists warn a new human pandemic could be on the horizon. But researchers at the La Jolla Institute for Immunology say our immune...