Sign in

Akaash Kumar

@akaashkumar.bsky.social
685 followers 723 following 19 posts

Interdisciplinary scientist interested in technology development, microscopy and biological sciences. Multispectral live cell imaging of membrane trafficking. MRC LMB, Cambridge, UK.

PostsRepliesMedia
Akaash Kumar @akaashkumar.bsky.social · 16/09/2025
In future work, I am now using our multispectral technology to study membrane trafficking pathways in cytotoxic T cells and related immunotherapies, to decode how T cells are able to eliminate virally-infected/cancer cells and what happens in patients when these processes go wrong. Updates to come!
040
Akaash Kumar @akaashkumar.bsky.social · 16/09/2025
We demonstrated the ability to simultaneously image trafficking of five different endogenous receptor classes using de-novo binders from David Baker's lab, by adding the multispectral technology to a state-of-the-art single objective light sheet microscope, capturing data at 3 volumes per second.
130
Akaash Kumar @akaashkumar.bsky.social · 16/09/2025
The technology we developed is compatible with any camera-based microscope and by using polycistronic plasmids and live-cell dyes (e.g. @spirochrome.com) we can image multiple organelles in live cells simultaneously.
130
Akaash Kumar @akaashkumar.bsky.social · 20/05/2025
Today's light sheet video of actin dynamics in cytotoxic t cells... so much fun to come!
0173
Akaash Kumar @akaashkumar.bsky.social · 13/12/2024
Simultaneous multispectral imaging of seven organelles in live cells using our multispectral spinning disk confocal microscope! #FluorescenceFriday You can read more about this technology in our updated pre-print: www.biorxiv.org/content/10.1...
0130
Akaash Kumar @akaashkumar.bsky.social · 22/11/2024
Some personal news: my wife and I are finally homeowners! We got the keys to our home in Cambridge today, very exciting times!
010
Akaash Kumar @akaashkumar.bsky.social · 20/11/2024
Hello Bluesky! I am an engineer/scientist currently working at the MRC LMB in Cambridge UK. During my PhD I developed new imaging technologies to shed light on the dynamics of living cells e.g. here is a movie of 6 organelles in live human cancer cells. Follow for more updates! #science #biology
15812