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Afshin Samali

@afshinsamali.bsky.social
251 followers 116 following 16 posts

ER Stress, Unfolded Protein Response, Cancer Biology

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Afshin Samali @afshinsamali.bsky.social · 23/07/2026
Our new commentary iMeta on Environmental Chemicals and the Tumor Immune Microenvironment onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Environmental chemicals and the tumor immune microenvironment
Impact of representative environmental chemicals on tumor immune microenvironment (TIME). Representative environmental chemicals are ubiquitously distributed across air, soil, aquatic systems, and bi...
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Afshin Samali @afshinsamali.bsky.social · 23/06/2026
Applications now open for the six-week Postgraduate Education Transition Programme (PETP), for refugees and International Protection Applicants interested in postgraduate study. 📍 Galway area 📝 Apply: forms.gle/yHqWDQjrTxpQ... #HigherEducation #RefugeesWelcome #Galway #PostgraduateStudy
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Afshin Samali @afshinsamali.bsky.social · 14/01/2026
Ceremony to accredit Iran's ambassador to Ireland postponed - New Iranian ambassador has been prevented from officially taking up duties because of the regime's response to protests in Iran. #Iran #DigitalBlackoutInIran #HumanRights #Solidarity www.rte.ie/news/ireland...
rte.ie
Ceremony to accredit Iran's ambassador postponed
The new Iranian ambassador to Ireland has been prevented from officially taking up their duties by the Department of Foreign Affairs because of the regime's response to protests in Iran.
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Afshin Samali @afshinsamali.bsky.social · 14/01/2026
At least 12,000, and possibly as many as 20,000 people have been killed in Iran in recent day. KILLINGS must STOP! #Iran #DigitalBlackoutInIran #HumanRights #Solidarity www.cbsnews.com/news/iran-pr...
cbsnews.com
Over 12,000 feared dead after Iran protests, as video shows bodies lined up at morgue
Information trickling out of Iran suggests a far deadlier crackdown on protesters than previously reported.
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NOELREPORTS @noelreports.com · 11/01/2026
Tehran out strong: A video obtained by Iran International shows that despite harsh repression and an internet blackout, people in Punak, Tehran gathered together, lit fires, and chanted protest slogans.
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Fared Al Mahlool | فريد المحلول @faredalmahlool.bsky.social · 12/01/2026
Tehran, Iran — crowds protest the ruling regime.
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Olga Nesterova @onestpress.onestnetwork.com · 12/01/2026
Iran Under Growing Pressure Amid Protest Death Toll and Reports of Imminent Execution www.onestnetwork.com/post/iran-un...
onestnetwork.com
Iran Under Growing Pressure Amid Protest Death Toll and Reports of Imminent Execution
Rights groups warn that if executions proceed, Iran could face deeper international isolation and escalating tensions with Western governmen
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Samali Foundation @samalifoundation.bsky.social · 23/12/2025
The Samali Foundation is pleased to be one of the recipients of the Refugee-led Innovation Fund 2025-2026 medium.com/@UNHCRInnova...
medium.com
The Refugee-led Innovation Fund welcomes a new cohort of changemakers
Across the world, organizations led by displaced and stateless people are innovating to support their communities. We’re right beside them.
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UNHCR, the UN Refugee Agency @unhcr.org · 02/12/2025
Over $1B pledged to UNHCR today is a strong signal of solidarity with people forced to flee. This is a crucial start for 2026, but we need this momentum to grow because funding gaps still put millions at risk. ℹ️ www.unhcr.org/news/press-r...
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Afshin Samali @afshinsamali.bsky.social · 27/11/2025
Grelet honored by international society for ‘groundbreaking’ work in mitochondrial biology- Nerve-to-cancer mitochondrial transfer #mitochondria #cancer #metastasis www.linkedin.com/redir/redire...
linkedin.com
Grelet honored by international society for ‘groundbreaking’ work in mitochondrial biology | USA Health
In his presentation, “Nerve-to-Cancer Mitochondrial Transfer: A Key Driver of Metastasis,” Grelet revealed a transformative mechanism by which neurons transfer their mitochondria to cancer cells, fuel...
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Afshin Samali @afshinsamali.bsky.social · 26/11/2025
NF-κB is a central regulator of hypoxia-induced gene expression | EMBO reports www.embopress.org/doi/full/10....
embopress.org
NF-κB is a central regulator of hypoxia-induced gene expression | EMBO reports
imageimageHypoxia induces a specific NF-κB-dependent gene signature across multiple cell systems. NF-κB is required for over 60% of gene repression occurring in response to hypoxia, controlling oxidat...
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Silicon Republic @siliconrepublic.bsky.social · 26/11/2025
The programme is designed to invest in research equipment from routine equipment that is used in higher education institutions to more advanced equipment that can be shared across several institutions as well as being accessible to external users.
siliconrepublic.com
€750m ‘Inspire’ investment aims to transform Ireland’s research infrastructure
Today saw the lunch of a new €750m investment fund to ensure Ireland's higher education sector has the equipment and infrastructure required to compete globally.
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The Irish Times @irishtimes.com · 25/11/2025
irishtimes.com
‘We don’t call India our home; we call Ireland our home because that’s where our home is’
Ankit Gulati felt a call to move abroad from Delhi after his father died at just 52
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Afshin Samali @afshinsamali.bsky.social · 20/11/2025
🎓 Want to do a PhD in cancer biology? ARC, @universityofgalway.bsky.social offering 2 funded #PhD positions (€25k + fees) starting in 2026. Focus: #IRE1 signaling in breast cancer. Apply by 12 Dec 2025 📧 afshin.samali@universityofgalway.ie #CancerResearch #TNBC #MolecularBiology #PhDPositions
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Afshin Samali @afshinsamali.bsky.social · 20/11/2025
🎓 Want to do a PhD in cancer biology? ARC, @universityofgalway.bsky.social offering 2 funded #PhD positions (€25k + fees) starting in 2026. Focus: #IRE1 signaling in breast cancer. Apply by 12 Dec 2025 📧 afshin.samali@universityofgalway.ie #CancerResearch #TNBC #MolecularBiology #PhDPositions
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School of Biological Sciences @cambridgebiosci.bsky.social · 13/11/2025
🔬 Experience Research Life at Cambridge! Applications are now open for the 2026 Experience Postgrad Life Sciences Programme. Gain hands-on lab experience with an 8-week summer placement, in partnership with @corpuscambridge.bsky.social! 🔗 www.exppg.lifesci.cam.ac.uk #SummerPlacement #Cambridge
2025 summer students in Cambridge
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Zoltan Molnar @zoltan-molnar.bsky.social · 11/11/2025
First-ever atlas of brain development shows how stem cells turn into neurons There are 6 excellent human brain development papers in Nature - www.nature.com/articles/d41... Check them out!
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Afshin Samali @afshinsamali.bsky.social · 03/11/2025
www.nature.com/articles/s41...
nature.com
Adaptive ER stress promotes mitochondrial remodelling and longevity through PERK-dependent MERCS assembly - Cell Death & Differentiation
Cell Death & Differentiation - Adaptive ER stress promotes mitochondrial remodelling and longevity through PERK-dependent MERCS assembly
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Afshin Samali @afshinsamali.bsky.social · 22/10/2025
Breastfeeding boosts anticancer immunity through recruitment of CD8+ T cells www.nature.com/articles/d41...
nature.com
Breastfeeding boosts immune cells that protect against breast cancer
The protective, long-lived T cells can persist for decades after a woman gives birth.
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New Scientist @newscientist.com · 20/10/2025
An analysis of patient records suggests that mRNA covid-19 vaccines boost the immune response to cancerous tumours when given soon after people start a type of immunotherapy, extending their lives
newscientist.com
mRNA covid vaccines spark immune response that may aid cancer survival
An analysis of patient records suggests that mRNA covid-19 vaccines boost the immune response to cancerous tumours when given soon after people start a type of immunotherapy, extending their lives
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New Scientist @newscientist.com · 20/10/2025
Scientists are designing mRNA vaccines to produce virus-like nanoparticles, which should lead to a more robust immune response with even fewer side effects than either of these immunisation approaches on their own
newscientist.com
Why the next generation of mRNA vaccines is set to be even better
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Afshin Samali @afshinsamali.bsky.social · 18/10/2025
A new blood test has been been approved by FDA to assist in diagnosing Alzheimer’s disease. go.nature.com/47b4hIp
go.nature.com
Blood tests are now approved for Alzheimer’s: how accurate are they?
A second blood test has been been approved by the US Food and Drug Administration to assist in diagnosing Alzheimer’s disease. Will these tests change how cognitive decline is measured?
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Nature @nature.com · 17/10/2025
A new blood test to aid with the diagnosis of Alzheimer’s disease has been approved by the US FDA go.nature.com/47b4hIp
go.nature.com
Blood tests are now approved for Alzheimer’s: how accurate are they?
A second blood test has been been approved by the US Food and Drug Administration to assist in diagnosing Alzheimer’s disease. Will these tests change how cognitive decline is measured?
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Susan Logue @loguesusan.bsky.social · 25/07/2025
Dissecting Branch-Specific Unfolded Protein Response Activation in Drug-Tolerant BRAF-Mutant Melanoma using Data-Independent Acquisition Mass Spectrometry - Molecular & Cellular Proteomics www.mcponline.org/article/S153...
mcponline.org
Dissecting Branch-Specific Unfolded Protein Response Activation in Drug-Tolerant BRAF-Mutant Melanoma using Data-Independent Acquisition Mass Spectrometry
Cells rely on the Unfolded Protein Response (UPR) to maintain ER protein homeostasis (proteostasis) when faced with elevated levels of misfolded and aggregated proteins. The UPR is comprised of three ...
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Afshin Samali @afshinsamali.bsky.social · 17/10/2025
Obesity gene shields against heart disease www.nature.com/articles/d41...
nature.com
This gene causes obesity — and shields against heart disease
People with certain forms of the MC4R gene have lower cholesterol levels than do other individuals with a high body-mass index.
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Research Ireland @researchireland.ie · 13/10/2025
The countdown to Science Week 2025 is on 🔬🗓️ Supported by Research Ireland, Science Week is marking its 30th anniversary this year! Festival and event details are coming soon! Stay tuned and keep an eye on www.scienceweek.ie for the latest updates. #ScienceWeek #ThenTodayTomorrow
Science Week Decorative graphic
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Afshin Samali @afshinsamali.bsky.social · 11/10/2025
How #immigration drives winning #science - "Talent can be born anywhere, but opportunities are not" www.nature.com/articles/d41...
nature.com
More than 30% of this century’s science Nobel prizewinners immigrated: see their journeys
The most common destination for eventual Nobel laureates in physics, chemistry and medicine since 2000 is the United States, Nature has found.
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Precision Oncology Ireland @precisiononcire.bsky.social · 08/10/2025
Since 2019, POI has worked to accelerate the development of personalised cancer therapy & diagnostic options. Today we begin Stage 2 of our journey, building on strong foundations and expanding our collaborations to drive innovation & shape the future of cancer care.
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Research Ireland @researchireland.ie · 08/10/2025
Minister James Lawless has launched Phase 2 of Ireland’s leading and largest ever cancer research programme, @precisiononcire.bsky.social. The programme is co-funded through Research Ireland, industry and the not-for-profit sector. Read more: www.researchireland.ie/news/precision-oncology-ireland/
Siobhan Gaynor, Advanced Cancer Patient Council member and patient researcher; Prof Donal Brenan, UCD Professor of Gynae-Oncology, Consultant Gynaecological Oncologist at the Mater Hospital, and Deputy-Director of POI; Prof Walter Kolch, Director of Precision Oncology Ireland and Systems Biology Ireland (based at UCD); Dr Siobhan Roche, Director of Science for the Economy, Taighde Éireann–Research Ireland; Prof Kate Robson Brown, UCD Vice-President for Research, Innovation and Impact.
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Precision Oncology Ireland @precisiononcire.bsky.social · 24/09/2025
Since 2019, POI has driven huge research impacts, from biological insights to training the next generation of researchers. On #WorldCancerResearchDay, we’re proud to share our new brochure, developed with science journalist Claire O'Connell, highlighting these achievements tinyurl.com/jnhs762h
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Afshin Samali @afshinsamali.bsky.social · 24/09/2025
No strong evidence for autism-Tylenol link. www.nature.com/articles/d41...
nature.com
Trump links autism and Tylenol: is there any truth to it?
The US president repeatedly advised people, “Don't take Tylenol,” but scientists say that strong evidence between the medication and autism is lacking.
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Afshin Samali @afshinsamali.bsky.social · 17/09/2025
Five problems plaguing publishing in the life sciences—and one common cause - Wright - 2024 - FEBS Letters - Wiley Online Library febs.onlinelibrary.wiley.com/doi/10.1002/...
febs.onlinelibrary.wiley.com
FEBS Press
Although publication in scholarly peer-reviewed journals remains the gold standard for communication of findings in the life sciences, the gold has been debased by various impurities. Here, I discuss...
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Afshin Samali @afshinsamali.bsky.social · 12/09/2025
Samali Foundation will be honoured for its work at the Mayo Irish Diaspora Society 2025 Awards ceremony, tomorrow 13 September, #Castlebar #Mayo.
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Andrew Kellett @akellett.bsky.social · 17/07/2025
Excited to share our @narjournal.bsky.social work on a trackable trinuclear platinum complex for breast cancer therapy: doi.org/10.1093/nar/... 🧬 With @raphael-depaiva.bsky.social @afshinsamali.bsky.social @alicepyne.bsky.social @westerlundlab.bsky.social @researchireland.ie @dcuresearch.bsky.social
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Afshin Samali @afshinsamali.bsky.social · 23/06/2025
It was lovely to interview with @sorchapollak.bsky.social @irishtimes.com regarding @samalifoundation.bsky.social #Education #Refugee www.irishtimes.com/ireland/soci...
irishtimes.com
Galway hotel fire ‘pulled our community together to help other newcomers’, says professor
Cancer specialist recalls 2023 incident as he launches foundation to help refugees and asylum seekers access education
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Samali Foundation @samalifoundation.bsky.social · 19/06/2025
Launch of Samali Foundation on 17 June @ria.ie. Speakers included Minister Colm Brophy, Pat Guiry (President @ria.ie), Enda O'Neill (@unhcr.org Ireland), @afshinsamali.bsky.social, @adriennegorman.bsky.social (@universityofgalway.bsky.social), Zarghona Hassani & Ismail Mohammed. #Refugee #Education
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Samali Foundation @samalifoundation.bsky.social · 13/06/2025
Former refugee on a mission to help others connachttribune.ie/former-refug...
connachttribune.ie
Former refugee on a mission to help others - Connacht Tribune - Galway City Tribune
Former refugee on a mission to help others
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