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adamgrippin.bsky.social

@adamgrippin.bsky.social
20 followers 66 following 0 posts

PGY5 RadOnc resident at @MDAndersonNews 🩺 | @UFMDPhD '21 | Translational research | Cancer Immunotherapy | RNA vaccines | views are my own

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The Venkatesh Lab @venkatesh-lab.bsky.social · 16/09/2025
We are excited to share the Venkatesh Lab’s first publication in collaboration with @michellemonje.bsky.social team uncovering how neuronal activity influences the progression of small cell lung cancer #SCLC in the lung and brain. www.nature.com/articles/s41...
nature.com
Neuronal activity-dependent mechanisms of small cell lung cancer pathogenesis - Nature
Glutamatergic and GABAergic (γ-aminobutyric acid-producing) cortical neuronal activity drives proliferation of small lung cell cancer via paracrine interactions and through synapses formed with tumour...
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Reposted by @adamgrippin.bsky.social
immunoboys @immunoboys.bsky.social · 11/09/2025
Plasmacytoid dendritic cells can transition to become cDC2s under to influence of TNF, while type-I interferon reduces TNFR expression and thereby inhibits transition. These transitioned cDC2 seem fully functional. 🧪 ⑂ Hornero et al 2025 in Nat Immunol www.nature.com/articles/s41...
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Reposted by @adamgrippin.bsky.social
Alex Rubinsteyn @alexr.bsky.social · 20/08/2025
"In vivo CAR T cell generation to treat cancer and autoimmune disease" ...as if millions of cell therapy CDMOs suddenly cried out in terror and were suddenly silenced... www.science.org/doi/10.1126/...
science.org
In vivo CAR T cell generation to treat cancer and autoimmune disease
Chimeric antigen receptor (CAR) T cell therapies have transformed treatment of B cell malignancies. However, their broader application is limited by complex manufacturing processes and the necessity f...
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Reposted by @adamgrippin.bsky.social
Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 09/08/2025
Congratulations @doudna-lab.bsky.social !! History will position her name alongside the likes of Darwin, Einstein, and Hodgkin.
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Reposted by @adamgrippin.bsky.social
Nature @nature.com · 02/08/2025
Hidden in the lungs of some breast cancer survivors are tumour cells that can remain dormant for decades — until they one day trigger a relapse go.nature.com/45uez6N
go.nature.com
‘Sleeping’ cancer cells in the lungs can be roused by COVID and flu
Nature - Inflammation from the respiratory infections seems to be the culprit, study in mice finds.
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Reposted by @adamgrippin.bsky.social
Wen Jiang MD, PhD @wenjiang-nano.bsky.social · 26/03/2025
Our latest paper in collaboration with @jacques-lux.bsky.social describing using #US to activate #sting for #cancerimmunotherapy is now online in AdvScience. @mdanderson.bsky.social @utswtxid.bsky.social
advanced.onlinelibrary.wiley.com
Targeted STING Activation Using Modified Ultrasound‐Responsive Microbubbles Enhances Immune Checkpoint Blockade Against Melanoma
This study explores the use of ultrasound contrast agents loaded with Stimulator of Interferon Genes (STING) agonists as an approach to activate the body's immune system against cancer. Termed Microb...
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Reposted by @adamgrippin.bsky.social
Nature Cancer @natcancer.nature.com · 22/03/2025
Betty Kim & Wen Jiang and colleagues report the design and characterization of an antibody–toxin conjugate targeting CD47, promoting anti-tumor immunity in preclinical cancer models. @bettykimmdphd.bsky.social @wenjiang-nano.bsky.social @mdanderson.bsky.social ⬇️ www.nature.com/articles/s43...
nature.com
An antibody–toxin conjugate targeting CD47 linked to the bacterial toxin listeriolysin O for cancer immunotherapy - Nature Cancer
Schrank et al. report the design and characterization of an antibody–toxin conjugate targeting CD47, promoting anti-tumor immunity in preclinical cancer models.
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