Sign in

St. Jude Children's Research Hospital

@stjuderesearch.bsky.social
915 followers 49 following 636 posts

Driving discoveries and innovative treatments for childhood cancer and other diseases. Ranked #3 by USNWR. #StJude #StJudeResearch

PostsRepliesMedia
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 13h
Bikoff linked a subgroup of spinal neurons, V1Pou6f2, to the speed of rhythmic movement. Loss of these neurons slowed locomotion without disrupting limb movements. bit.ly/4g1d58f
010
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 13h
@lindsayschwarz.bsky.social mapped a stress-related brain circuit linking C1 neurons to a key brain region. Prolonged activation produced lasting anxiety-like behavior, while inhibition reduced it. bit.ly/4ycfmph
100
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 13h
@labogden.bsky.social identified arachidonic acid as a regulator of Smoothened signaling. Blocking the interaction disrupted heart and lung development while leaving nervous system development unaffected. bit.ly/4xqCSOv
111
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 13h
Baker found the H3.3 K27M mutation keeps brainstem precursor cells in an immature, actively dividing state, shedding light on why diffuse midline glioma commonly develops in this region. bit.ly/4y3AHka
100
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 13h
Research from Suzanne Baker, PhD; Stacey Ogden, PhD; Lindsay Schwarz, PhD; and Jay Bikoff, PhD, reveals how development shapes brain tumors, organ formation, anxiety and movement, connecting molecular and cellular mechanisms with disease and potential therapeutic targets Learn more 🧪⤵️
120
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 17h
A study by St. Jude scientists showed childhood cancer survivors living in the most vulnerable neighborhoods had twice the chronic disease burden of those in the least vulnerable areas. The findings highlight the need to integrate neighborhood-level factors into survivorship care. bit.ly/47T5i8L
bit.ly
Neighborhood conditions linked to childhood cancer survivors' long-term health
Discover how the St. Jude Lifetime Cohort Study uncovered community-level factors influencing chronic health condition risks, and how that can improve care.
010
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 08/10/2026
🧪 Learn how these findings can improve the ability to study disease linked to poor outcomes and provide new patient-derived models to help evaluate potential treatment strategies: bit.ly/4hDnGIM
bit.ly
Scientists identify the neuroblastoma cells that signal poor outcomes
Explore new research that created better patient-derived models of the pediatric cancer’s high-risk variants and uncovered how to identify mesenchymal cells.
010
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 08/10/2026
St. Jude scientists and collaborators built a comprehensive dataset of neuroblastoma samples, incorporating multiple leading-edge technologies, to identify a gene expression signature that distinguishes high-risk, treatment-resistant neuroblastoma cells from lower-risk cells.
110
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 01/10/2026
Looking to expand your perspective on pediatric cancer research? Hear why postdoctoral research associate Tuyu Zheng, PhD, recommends The Science of Childhood Cancer virtual lecture series for trainees and early-career researchers. Join upcoming lectures through Nov. 19: bit.ly/3TD4Rvy
010
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 29/09/2026
Among those sharing advances in pediatric cancer in plenary sessions were Noha Shendy, PhD; Mark Hatley, MD, PhD; and Alejandro Gutierrez, MD. Shendy, Grace McKay-Corkum, MD, and Mohammad Ali Mohammad Nezhady, PhD, also presented abstracts. #AACRpediatrics26
001
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 29/09/2026
St. Jude researchers attended the @theaacr.bsky.social Special Conference in Cancer Research which focused on bridging discovery and clinical impact in pediatric cancer. @cmullighan.bsky.social gave the keynote address on working toward a cure for acute leukemia through the lens of genomics.
100
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 25/09/2026
Across St. Jude, postdoctoral researchers spend countless hours conducting experiments, analyzing data and advancing the research that powers our mission. As #NPAW comes to a close, we celebrate the impact of our postdocs who help make world-class science possible at St. Jude.
000
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 24/09/2026
Proud to be ranked No. 1 on @forbes.com' 2026 list of America's Best Employers for Healthcare Professionals. We're committed to supporting the people who advance the St. Jude mission every day, from patient care and research to the many roles that make our work possible.
020
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 24/09/2026
KDM2B is a potential therapeutic target in Group 3 and Group 4 medulloblastoma. Researchers found that removing the gene or degrading the protein slowed tumor growth and prolonged survival in preclinical models, offering a strategy for high-risk tumors that lack targeted therapies. 🧪 bit.ly/4jnzC2h
bit.ly
KDM2B revealed as a selective dependency in high-risk medulloblastoma subgroups
Explore a shared vulnerability in two of the childhood brain tumor's types, opening opportunities for targeted therapies in patients with high-risk disease.
000
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 24/09/2026
By aligning country leadership, lived experience and proven interventions, OneSCD aims to accelerate progress toward more equitable diagnosis, treatment and care for children and families affected by sickle cell disease.
000
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 24/09/2026
At the United Nations General Assembly, St. Jude Children's Research Hospital joined global partners, including @who.int, @unicef.org, Africa CDC and the World Coalition on Sickle Cell Disease to launch OneSCD, a new initiative that will strengthen and connect sickle cell disease efforts worldwide.
110
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 23/09/2026
St. Jude scientists identified ZMYND8 as a major regulator of CD8+ T-cell exhaustion. Targeting the gene improved immune function and enhanced immunotherapy, offering a potential new strategy to strengthen anti-tumor responses in solid tumors. 🧪 bit.ly/3TiiMrc
stjude.org
Targeting ZMYND8 improves T-cell function and may boost immunotherapy
Explore new St. Jude research finding how removing the immune response “brake” gene ZMYND8 led to better control of solid tumors and chronic viral infections.
010
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 21/09/2026
During Postdoc Appreciation Week, St. Jude faculty are sharing messages of gratitude for the postdocs whose talent, dedication and discoveries help advance our mission. Thank you to all our postdocs! #NPAW
020
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 18/09/2026
Congratulations to Duffy on receiving both the Young SIOP Leadership Assembly Award and the Young Investigator Award!
000
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 18/09/2026
At #SIOP2026, Caitlyn Duffy, MD, MPH, shared how the ARIA Guide is helping expand access to evidence-based childhood cancer care worldwide. Developed through worldwide collaboration, ARIA provides resource-stratified clinical guidance designed for a wide range of care settings. Learn more:
100
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 18/09/2026
St. Jude survivorship research was also presented as part of a late-breaking session at SIOP 2026. Together, the work advances understanding of survivor-specific risks and helps inform strategies that may improve long-term health and quality of life for childhood cancer survivors.
010
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 18/09/2026
St. Jude researchers shared work on physical activity interventions, cardiovascular risk after platinum chemotherapy, genetic factors linked to long-term health outcomes, and the connections between sleep health, psychological distress and social determinants.
110
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 18/09/2026
Survivorship research featured at #SIOPcongress explored how to improve life after childhood cancer.
130
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 17/09/2026
Congratulations to Michael McNeil, MD, MPH, director of the St. Jude Global Palliative Care Program, who received the 2026 SIOP North America Rising Star Award for advancing culturally relevant, sustainable approaches to pediatric palliative care through global collaboration.
010
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 16/09/2026
“Experience matters when thinking about a good outcome. It’s not just the surgeon, it’s the whole team,” Davidoff said. #SIOPcongress #SIOP2026
000
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 16/09/2026
Drawing on 147 patients with bilateral Wilms tumor treated at St. Jude, where 87% kept parts of both kidneys, he highlighted advances in surgical technique, imaging and multidisciplinary care.
100
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 16/09/2026
Andrew Davidoff, MD, shared lessons from 25 years of kidney-sparing surgery during a keynote at the International Society of Paediatric Oncology (SIOP).
110
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 15/09/2026
For the 19th consecutive year, St. Jude has been recognized in the @usnews.com “Best Children’s Hospitals” list, ranking third among the best hospitals for pediatric cancer care. Read more: bit.ly/4gT6ajh
010
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 14/09/2026
Building on the foundation created by longstanding resources such as the Childhood Cancer Survivor Study and St. Jude LIFE, she aims to advance research related to wellness, diet and quality of life. 🧪 Learn more about Tonorezos and her vision for St. Jude: bit.ly/4j3cmq8
bit.ly
5 Questions for Emily Tonorezos, MD, MPH
Meet Emily Tonorezos, MD, MPH, the incoming St. Jude Division of Cancer Survivorship director, and learn about her prior research and plans for the program.
000
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 14/09/2026
Emily Tonorezos, MD, MPH, incoming director of the Division of Cancer Survivorship, is motivated to help shape the future of survivorship science at St. Jude. “This work should always be guided by the people we are trying to help — survivors and their families,” Tonorezos said.
100
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 10/09/2026
From global health and survivorship to nursing leadership and implementation science, we'll be sharing work aimed at strengthening childhood cancer care worldwide. Follow along for highlights throughout the week. #StJudeResearch
000
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 10/09/2026
St. Jude experts, Global Scholars, trainees and collaborators are heading to #SIOP2026 in San Antonio next week.
110
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 10/09/2026
The free symposium will feature keynote speakers from Hugging Face, the University of Chicago and Siemens, along with presentations from St. Jude researchers, workshops, collaborative discussions and poster sessions. Secure your spot at #KIDS26: bit.ly/4A3o5uW
bit.ly
Knowledge in Data Science Symposium (KIDS26)
Join us November 16-18, 2026 for a symposium that will enrich the collaborative data science culture by sharing and brainstorming ways to gain the most valuable scientific knowledge from biomedical da...
000
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 10/09/2026
Attend the Knowledge in Data Science (KIDS) Symposium, Nov. 16-18 in Memphis or virtually from anywhere in the world, to explore how data science, AI and collaboration are driving advances in pediatric research and innovation.
100
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 10/09/2026
Welcome @zhengwu1.bsky.social! Excited to have you here.
000
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 08/09/2026
St. Jude is leveraging survivorship expertise to study the long-term health of children treated with experimental CAR T cells, regardless of where they received care. CONQUER could help guide follow-up care and future pediatric immunotherapies. 🧪 bit.ly/46qHqsJ
000
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 08/09/2026
Register for virtual access: www.stjudeglobalevents.org/event/UNGA20...
000
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 08/09/2026
Join us on Sept. 23 for this virtual event as government leaders, global health experts, civil society representatives, and people with lived experience come together to discuss how collective action can help advance more equitable outcomes worldwide. @who.int @unicef.org
110
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 08/09/2026
That's why St. Jude is joining global partners at #UNGA81 for the launch of the #OneSCD Partnership, a new effort to strengthen collaboration, align priorities and accelerate progress for children and families affected by sickle cell disease around the world.
100
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 08/09/2026
Where a child is born should not determine their access to sickle cell disease care. Yet for more than 7 million people living with sickle cell disease worldwide, access to timely diagnosis, treatment and comprehensive care remains far from equitable.
132
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 03/09/2026
🧪 Learn more about SAGES1: www.stjude.org/research/why...
stjude.org
SAGES1 Employs the Powerful Potential of Gene Editing for Sickle Cell Disease
SAGES1, a clinical trial testing a gene editing approach sickle cell disease is significant because every aspect of the trial occurs on the St. Jude campus.
000
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 03/09/2026
A decade of discovery helped advance SAGES1, a St. Jude clinical trial evaluating a novel CRISPR-Cas9 gene editing approach for sickle cell disease. The trial builds on findings from the lab of Mitchell Weiss, MD, PhD, and is led by @akshaysharma.bsky.social. #SickleCellAwarenessMonth
100
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 01/09/2026
St. Jude researchers and collaborators developed AdaptiveFlow, an AI-informed platform, that can virtually screen 69 billion drug-like molecules with a 1,000-fold reduction in computational costs. Learn how this open-source platform could help accelerate therapeutic discovery: LINK 🧪 bit.ly/4zQuERq
bit.ly
AI-informed AdaptiveFlow redefines large-scale cloud computing for drug discovery
See how a machine-learning drug discovery platform for ultra-large virtual screenings called AdaptiveFlow guides the rational selection for deeper exploration
010
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 28/08/2026
Mentors have shaped every stage of Sarada Achyutuni, PhD's scientific journey. At St. Jude, guidance from Jian Xu, PhD, and Min Ni, PhD, helps inform her research into how lineage identity, cell of origin and genetic alterations shape leukemia metabolism. Learn more about Achyutuni 🧪 bit.ly/4qERxmM
000
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 26/08/2026
Researchers showed that brain cells respond differently to the H3.3 K27M mutation depending on their location in the developing brain. The findings help explain why diffuse midline glioma (DMG) develops where it does and identify potential therapeutic targets. bit.ly/4y3AHka
bit.ly
Findings demonstrate how mutation disrupts cell development, driving region-specific brain tumors
Discover how St. Jude researchers uncovered how regional differences in the developing brain shape diffuse midline glioma formation.
011
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 25/08/2026
Jeremy Slone, MD, MPH, has been named medical director of the St. Jude Affiliate Program Office. In this role, he will lead a network of six affiliate sites and one satellite across six states that helps expand access to clinical trials and allows patients to receive care closer to home.
010
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 25/08/2026
Scientists found that CAR T cells lacking the gene for Regnase-1 are more effective at treating osteosarcoma in preclinical models, controlling tumor growth and preventing lung metastasis. The findings support the development of an early-phase St. Jude clinical trial. bit.ly/4zxirRz
stjude.org
Removing immune ‘brake’ improves CAR T–cell therapy for osteosarcoma
Explore a cellular immunotherapy that controlled relapsed bone cancer and prevented metastasis in model systems, setting the foundation for a clinical trial.
010
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 20/08/2026
Inherited genetic changes can shape cancer risk across families. Kim Nichols, MD, and the St. Jude Cancer Predisposition Clinic are using genomic research to identify risk earlier and inform screening, surveillance and prevention. Learn more: bit.ly/4ieBgTp 🧪
010
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 18/08/2026
As Dr. Roberts prepares to lead St. Jude into its next chapter, his scientific vision and collaborative approach position the institution to continue advancing its mission for children everywhere. Explore the full announcement 🧪 bit.ly/4xcomtO
bit.ly
Charles W.M. Roberts, MD, PhD, named president and CEO of St. Jude Children’s Research Hospital
The Board of Governors announce Charles W.M. Roberts, MD, PhD, as the next president and CEO of St. Jude. Roberts will step into the role effective January 1, 2027.
010
St. Jude Children's Research Hospital @stjuderesearch.bsky.social · 18/08/2026
Dr. Roberts’ background in cancer epigenetics, clinical care and collaborative leadership has helped shape major efforts that connect researchers, clinicians and partner institutions to move discovery forward.
110