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Zheng Wu

@zhengwu1.bsky.social
158 followers 237 following 8 posts

Postdoc at Ralph DeBerardinis’s lab at UT Southwestern Medical Center via Yale and Salk Institute. Recipient of NIH Pathway to Independence Award (K99/R00) Interested in #mitochondria, #metabolism and innate immunity.

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Reposted by Zheng Wu
Stylianos Lefkopoulos (he/him) @slefkopoulos.bsky.social · 30/12/2025
3rd: conclusion/impact/implications 1 sentence is often enough; sometimes 2 are necessary. Provide a short, concise conclusion - what is the punchline? Do you have sth *important* to comment on regarding implications? Could be therapeutic implications or a finding that changes a dogma. Be specific.
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Reposted by Zheng Wu
Stylianos Lefkopoulos (he/him) @slefkopoulos.bsky.social · 30/12/2025
2nd: the findings The longest and main part of your abstract. Here you should explain: i) what you did and how ii) what you found An effective abstract doesn’t bombard the reader with details; you can’t describe all your results. Stick to major. *Must*: use friends from other fields as beta readers
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Reposted by Zheng Wu
Stylianos Lefkopoulos (he/him) @slefkopoulos.bsky.social · 30/12/2025
1st: 1-2 (max) sentences - intro Present the known and its caveat. It can be as brief as 1 sentence (we know x, but y (somehow linked to x) is unknown) or 2 sentences. My view is that abstracts with more than 2 introductory sentences rarely work well. Specific, clear, only the absolutely necessary.
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Reposted by Zheng Wu
Christian Frezza @frezzalab.bsky.social · 07/11/2025
NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT | Science www.science.org/doi/10.1126/... Great work from @rjdlab.bsky.social !!
science.org
NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT
Cells generate purine nucleotides through de novo purine biosynthesis (DNPB) and purine salvage. Purine salvage represses DNPB to prevent excessive purine nucleotide synthesis through mechanisms that ...
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Zheng Wu @zhengwu1.bsky.social · 06/11/2025
Super excited to share that my second project in the @rjdlab.bsky.social is now published in Science! Many thanks to all co-authors, especially @ptnguyen.bsky.social for his expertise in structural biology and enzymology! And big thanks to Ralph for his incredible mentorship and support!
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Reposted by Zheng Wu
DeBerardinis Lab at UT Southwestern Medical Center @rjdlab.bsky.social · 25/09/2025
Remarkable new human proteome-wide effort to predict protein-protein interactions using coevolutionary signals and deep learning. From Qian Cong in the Eugene McDermott Center at UT Southwestern. www.science.org/doi/10.1126/...
science.org
Predicting protein-protein interactions in the human proteome
Protein-protein interactions (PPI) are essential for biological function. Coevolutionary analysis and deep learning (DL) based protein structure prediction have enabled comprehensive PPI identificatio...
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Zheng Wu @zhengwu1.bsky.social · 19/08/2025
I’m thrilled to share that I have been awarded an NIH/NIGMS K99 Pathway to Independence Award. I’m deeply grateful to everyone who has supported me along the way, especially @rjdlab.bsky.social @cri-utsw.bsky.social
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Reposted by Zheng Wu
Trevor Tippetts @trevortippetts.bsky.social · 12/12/2024
Happy Holidays from the best group you’ll find! @rjdlab.bsky.social celebrating with the McDermott Center!
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Reposted by Zheng Wu
DeBerardinis Lab at UT Southwestern Medical Center @rjdlab.bsky.social · 05/12/2024
Join us in Austin, TXm Feb 9-10 2025, for an Abcam-sponsored symposium on Cancer and Metabolism. -RJD events.abcam.com/event/cancer...
events.abcam.com
Home - Cancer and Metabolism
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Reposted by Zheng Wu
DeBerardinis Lab at UT Southwestern Medical Center @rjdlab.bsky.social · 15/11/2024
New from Cold Spring Harbor Press. Available in December, 2024, just in time for the holidays! -RJD
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