Reposted by Zheng WuStylianos Lefkopoulos (he/him) @slefkopoulos.bsky.social · 30/12/20253rd: conclusion/impact/implications 1 sentence is often enough; sometimes 2 are necessary. Provide a short, concise conclusion - what is the punchline? Do you have sth *important* to comment on regarding implications? Could be therapeutic implications or a finding that changes a dogma. Be specific. 121
Reposted by Zheng WuStylianos Lefkopoulos (he/him) @slefkopoulos.bsky.social · 30/12/20252nd: the findings The longest and main part of your abstract. Here you should explain: i) what you did and how ii) what you found An effective abstract doesn’t bombard the reader with details; you can’t describe all your results. Stick to major. *Must*: use friends from other fields as beta readers 011
Reposted by Zheng WuStylianos Lefkopoulos (he/him) @slefkopoulos.bsky.social · 30/12/20251st: 1-2 (max) sentences - intro Present the known and its caveat. It can be as brief as 1 sentence (we know x, but y (somehow linked to x) is unknown) or 2 sentences. My view is that abstracts with more than 2 introductory sentences rarely work well. Specific, clear, only the absolutely necessary. 011
Reposted by Zheng WuChristian Frezza @frezzalab.bsky.social · 07/11/2025NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT | Science www.science.org/doi/10.1126/... Great work from @rjdlab.bsky.social !!science.orgNUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPATCells generate purine nucleotides through de novo purine biosynthesis (DNPB) and purine salvage. Purine salvage represses DNPB to prevent excessive purine nucleotide synthesis through mechanisms that ... 0104
Zheng Wu @zhengwu1.bsky.social · 06/11/2025Super excited to share that my second project in the @rjdlab.bsky.social is now published in Science! Many thanks to all co-authors, especially @ptnguyen.bsky.social for his expertise in structural biology and enzymology! And big thanks to Ralph for his incredible mentorship and support! 1204
Reposted by Zheng WuDeBerardinis Lab at UT Southwestern Medical Center @rjdlab.bsky.social · 25/09/2025Remarkable new human proteome-wide effort to predict protein-protein interactions using coevolutionary signals and deep learning. From Qian Cong in the Eugene McDermott Center at UT Southwestern. www.science.org/doi/10.1126/...science.orgPredicting protein-protein interactions in the human proteomeProtein-protein interactions (PPI) are essential for biological function. Coevolutionary analysis and deep learning (DL) based protein structure prediction have enabled comprehensive PPI identificatio... 1296
Zheng Wu @zhengwu1.bsky.social · 19/08/2025I’m thrilled to share that I have been awarded an NIH/NIGMS K99 Pathway to Independence Award. I’m deeply grateful to everyone who has supported me along the way, especially @rjdlab.bsky.social @cri-utsw.bsky.social 3242
Reposted by Zheng WuTrevor Tippetts @trevortippetts.bsky.social · 12/12/2024Happy Holidays from the best group you’ll find! @rjdlab.bsky.social celebrating with the McDermott Center! 0155
Reposted by Zheng WuDeBerardinis Lab at UT Southwestern Medical Center @rjdlab.bsky.social · 05/12/2024Join us in Austin, TXm Feb 9-10 2025, for an Abcam-sponsored symposium on Cancer and Metabolism. -RJD events.abcam.com/event/cancer...events.abcam.comHome - Cancer and Metabolism 14513
Reposted by Zheng WuDeBerardinis Lab at UT Southwestern Medical Center @rjdlab.bsky.social · 15/11/2024New from Cold Spring Harbor Press. Available in December, 2024, just in time for the holidays! -RJD 1739