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Scripps Research

@scripps.edu
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Scripps Research is one of the world's largest, private, non-profit biomedical research organizations. We are Science Changing Life.

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Scripps Research @scripps.edu · 32m
Christian Diercks invited us into his lab, where he and his colleagues developed T7-ORACLE, a system that continuously mutates selected genes inside E. coli, generating new versions of the proteins they produce. Researchers can then select variants with useful new functions and continue the process.
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Scripps Research @scripps.edu · 23h
According to WHO, cancer causes nearly 1 in 5 deaths worldwide. Scripps Research scientists study cancer from individual proteins to whole cells and tissues, uncovering vulnerabilities and advancing promising ideas toward new therapies. More: ow.ly/z4kk50ZXiV0 #BreastCancerAwarenessMonth
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Scripps Research @scripps.edu · 12/10/2026
Scripps Research alum Linda Kidd, DVM, PhD, has received the 2026 University of Wisconsin School of Veterinary Medicine Alumni Achievement Award, recognizing her contributions to veterinary medicine, biomedical science and the broader community. More: ow.ly/2RBR50ZWZEV
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Scripps Research @scripps.edu · 10/10/2026
We’re still buzzing from Discovery Day! 🔬🌟 Visitors built DNA candy models, explored viruses through virtual reality and enjoyed hands-on science with our graduate students and postdocs. Thank you to everyone who joined us and made it possible! More moments to come!
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Scripps Research @scripps.edu · 10/10/2026
Congrats to Assoc. Prof. Keren Lasker on receiving a 2026 DARPA Young Faculty Award to engineer biomolecular condensates as “toxin traps” that capture and neutralize toxins. Once developed, Assoc. Prof. Michael G. Constantinides will lead preclinical studies evaluating their effectiveness.
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Scripps Research associate professor Keren Lasker receives DARPA Young Faculty Award to develop “toxin traps” - Scripps Research
The up to $1.14 million award will support engineering of a new method to capture and destroy toxins, which could eventually be used to prevent or limit harm from exposure.
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Reposted by Scripps Research
HHMI @hhmi-science.bsky.social · 07/10/2026
Proteins can reshape themselves in less than a millisecond. Now, #HHMIInvestigator Dorothee Kern & team @scripps.edu have developed a machine learning model to predict these rapid changes, & it could help researchers uncover new connections between protein movement & human health: bit.ly/4d6klPH
HHMI Investigator Dorothee Kern stands smiling with one hand on her hip beside a large white cylindrical scientific instrument marked with blue lettering. She wears a sleeveless black top with a woven neckline and ruffled front, a wide white woven belt with an oversized silver buckle, and white pants. Behind her are a wooden support beam, equipment cabinets, and an orange warning light.
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Reposted by Scripps Research
The Gairdner Foundation @gairdnerawards.bsky.social · 08/10/2026
Join Dr. Kelly to explore how his research on protein aggregation led to the discovery of tafamidis, the first effective drug for slowing the progression of a human amyloid disease. 📆Oct 22 | 9AM 📍Toronto & Online 🎟️Free 🔗https://bit.ly/InternationalSymposium2026 #GairdnerScienceWeek @scripps.edu
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Scripps Research @scripps.edu · 09/10/2026
Scripps Research EVP Eric Topol is among 100 scientists featured in The New York Times' “Unknowns” project, which explores some of science’s biggest unanswered questions. His question: Can the human aging process be safely reversed?
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What Are the Biggest Questions in Science Today? 100 Scientists Weigh In.
We asked 100 scientists about unsolved problems in their fields. They sent back provocations — on the origins of life, the possibilities for human progress and much more.
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Scripps Research @scripps.edu · 08/10/2026
At the Scripps Research Biotech Innovation Summit, attendees will get an exclusive look at these emerging Scripps Research technologies and the scientists advancing them. 🗓️ Join us on Oct. 22, 2026 | Scripps Research, La Jolla 🎟️ View the program and request to attend: techsummit.scripps.edu/agenda/
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Scripps Research @scripps.edu · 07/10/2026
Congrats to Asst. Prof. Alejandra Mendoza, recipient of a Discovery Grant from the National Psoriasis Foundation for her work investigating how sensory neurons detect early signals in inflamed skin and communicate with immune cells to regulate inflammation during psoriasis. ow.ly/vyap50ZVwZW
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Scripps Research @scripps.edu · 06/10/2026
In our last Front Row lecture, Associate Professor Giordano Lippi explored how tiny molecules called microRNAs help control production of the right proteins at the right place and time to build complex networks that drive thought, learning and behavior. Watch now: ow.ly/OJPY50ZV9nv
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Scripps Research @scripps.edu · 03/10/2026
Lights, camera, science! 🎬🔬 Scripps Research Prof. Luke Wiseman and our graduate students joined KUSI News for a sneak peek of tomorrow’s #DiscoveryDay, featuring liquid-nitrogen ice cream and silver mirrors! 🍦🪩
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KUSI Previews Scripps Research Discovery Day
YouTube video by Beck Ellman Heald Media Center
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Scripps Research @scripps.edu · 02/10/2026
Here’s a sneak peek at tomorrow’s Discovery Day! Before you join us, check out these helpful details 👇 🎟️ Register on-site. 🚗 Complimentary parking is available. 🌮 Food trucks will be on site. 🧪 Enjoy activities for all ages! 📲 Find directions and FAQs at scripps.edu/discoveryday.
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Scripps Research @scripps.edu · 02/10/2026
Scripps Research scientists describe in Proceedings of the National Academy of Sciences an engineered small protein that binds immune receptor TLR4 within cell membranes and reduces signals that can drive inflammation, pointing to a potential drug target for inflammatory diseases.
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Computer-designed protein targets immune receptor linked to inflammation at a new “undruggable” site - Scripps Research
Scripps Research scientists engineered a small protein that binds to the immune receptor TLR4 within cell membranes and reduces signals that can drive inflammation, pointing to a potential drug target for inflammatory diseases.
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Scripps Research @scripps.edu · 30/09/2026
New global rankings place Scripps Research among the world’s top 200 institutions for regenerative medicine in the 2026 Nature Index supplement, which explores the discoveries driving the field and the challenges that could limit its progress. See the full list: ow.ly/AVMY50ZTjTq
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Scripps Research @scripps.edu · 29/09/2026
According to American Heart Association, heart disease claims nearly 950K U.S. lives a year and is the world’s leading cause of death. For #WorldHeartDay, explore how Scripps Research is addressing its roots through first-in-class therapy, regenerative medicine and AI.
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Heart Disease - Scripps Research
Gain insight into the many ways our scientists seek to protect the heart, from predicting disease onset to creating regenerative medicines.
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Scripps Research @scripps.edu · 28/09/2026
In our recent livestream, researchers took viewers inside the Scripps Research NMR Core Facility to demonstrate how samples are prepared and analyzed to reveal detailed information about molecular structure and dynamics. 📲 Watch the full tour: www.youtube.com/live/03V1z_M...
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LIVE from the Scripps Research NMR Core
YouTube video by Scripps Research
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Scripps Research @scripps.edu · 23/09/2026
At the Scripps Research Translational Institute, a team led by Eric Topol is studying whether exercise, nutrition and cognitive coaching programs can influence Alzheimer’s-related biomarkers in people at increased risk. Learn more: ow.ly/GQKN50ZQi9C #WorldAlzheimersMonth
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Scripps Research @scripps.edu · 16/09/2026
Prof. Li Ye (Ye Lab) has been named a finalist for the prestigious Blavatnik National Awards for Young Scientists in the Life Sciences category! Ye is recognized for his work pioneering new techniques and uncovering complex energetic communications between the brain and body in health and disease.
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Scripps Research professor Li Ye named finalist for Blavatnik National Awards for Young Scientists - Scripps Research
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Scripps Research @scripps.edu · 16/09/2026
What’s ahead at the 2026 Biotech Innovation Summit? 🔬 Faculty spotlights on new technologies 🤖 AI-enabled Scripps Research discoveries 💊 Clinical-stage programs & digital clinical trials 💡 Industry and investor perspectives 🤝 Lean-In Sessions and interactive networking 🎟️ ow.ly/wsEu50ZGIao
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Scripps Research @scripps.edu · 16/09/2026
Congrats to Hannah Tam, one of six 2026 International Birnstiel Award laureates! A postdoctoral fellow in Ardem Patapoutian's lab, Tam’s doctoral research at Harvard University found in preclinical models that skin regeneration after birth is not lost but blocked. More: ow.ly/jhYs50ZO1CC
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Scripps Research @scripps.edu · 14/09/2026
Inside the Department of Integrative Structural & Computational Biology, scientists combine structural and computational methods to understand complex biological systems and pave the way for the next generation of drugs and precision therapies. 🔗 More: ow.ly/OcPx50ZNv6E
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Scripps Research @scripps.edu · 14/09/2026
We’re just a few weeks away from Discovery Day! 🔬 Explore hands-on science, watch live demos and see what it’s like to be a scientist for the day with Scripps Research scientists and graduate students. 📅 Oct. 3 | 10 AM–2 PM 📍 Scripps Research, La Jolla 🎟️ FREE tickets: ow.ly/OvoB50ZN2Hc
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Scripps Research @scripps.edu · 12/09/2026
In a new study, Scripps Research Prof. Jeffery Kelly and colleagues reveal a previously unknown way that the protein transthyretin (TTR) can unfold and break down. The alternative pathway is accessible to some TTR variants, particularly those that cause amyloidosis in the brain.
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Scientists discover a new way that a disease-linked protein comes apart - Scripps Research
New findings from Scripps Research and the University of Illinois Urbana-Champaign reveal a previously unknown way that the protein transthyretin can unfold and break down, and how it may contribute to rare forms of amyloid disease.
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Scripps Research @scripps.edu · 09/09/2026
Meet Assoc. Prof. Giordano Lippi, who leads a team at Scripps Research studying how microRNAs regulate gene expression during neuronal development and developing tools to precisely target disease-relevant microRNA–mRNA interactions.
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Scripps Research @scripps.edu · 09/09/2026
How does addiction change the brain? 🧠 Addiction reshapes brain circuits that control reward, stress and decision-making. Our scientists study these changes to translate discoveries into new ways to prevent substance use disorders, reduce cravings and support recovery.
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Addiction - Scripps Research
We study addiction biology from molecules to behavior. See how we're creating safer, more effective medicines and vaccines for this chronic disorder.
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Scripps Research @scripps.edu · 07/09/2026
It was a full house at our last Front Row! 👏 Scripps Research professor Ryan Shenvi shared how modern computation can help scientists narrow choices, reduce trial and error and find more efficient ways to make molecules. Watch the full talk and read the key takeaways: ow.ly/b7pi50ZEWXY
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Scripps Research @scripps.edu · 06/09/2026
📣 Hey San Diego families! Discovery Day is back, and this year, we’re bringing the fun to the Scripps Research campus! Join us for a FREE, family-friendly day of hands-on science, exciting demonstrations and opportunities to meet our scientists and graduate students. 🎟️ ow.ly/QNXz50ZJBuM
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Scripps Research @scripps.edu · 05/09/2026
Scripps Research professor Chi-Huey Wong will receive the 2027 American Chemical Society Alfred Bader Award for his work to understand carbohydrate chemistry and its roles in health and disease. He will be honored at the ACS Spring meeting in New Orleans. More: ow.ly/3V1X50ZJFGv
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Scripps Research @scripps.edu · 04/09/2026
Congratulations to Scripps Research EVP Eric Topol, M.D., on being named a 2026 Fierce 50 Leadership Honoree. In a profile, Fierce Pharma traces his nearly five decades of work in cardiology, genomics, AI, digital health and individualized medicine. Read more: ow.ly/obne50ZJB7S
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Scripps Research @scripps.edu · 04/09/2026
We’re LIVE! Tune in now 📲 www.youtube.com/live/03V1z_M...
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Welcome to our live show!
YouTube video by Scripps Research
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Scripps Research @scripps.edu · 04/09/2026
Today’s the day! 🎉🔬Meet the team taking you behind the scenes of the Scripps Research NMR Core Facility! Join us LIVE today at 11 a.m. PT to see NMR technology in action, learn how scientists study molecules at the atomic level and ask your questions during our live Q&A. 📲 ow.ly/UKKm50ZzxvN
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Scripps Research @scripps.edu · 04/09/2026
Rehearsal complete! ✅ The NMR Live team is ready to take you behind the scenes of the Scripps Research NMR Core. Join us tomorrow, Friday, September 4, at 11 a.m. PT for a live tour, and bring your questions for our experts to answer during the Q&A! Watch live on YouTube: ow.ly/UKKm50ZzxvN
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Scripps Research @scripps.edu · 03/09/2026
Dyna-1, developed by Scripps Research professor Dorothee Kern and colleagues, predicts micro-to-millisecond protein dynamics in roughly 30 seconds. Published in Nature, the model was trained on missing NMR assignments to identify protein regions likely to move.
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Where milliseconds matter: Scripps Research scientists build new ML model to predict protein movements essential for biological function - Scripps Research
Protein dynamics in the micro-to-millisecond timescale once took months of experiments to characterize. Dyna-1 can now predict them in roughly 30 seconds.
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Scripps Research @scripps.edu · 02/09/2026
ECG-CLIP outperformed other ECG foundation models when labeled data were limited, as few as 10 positive examples of a disease. The Lancet Digital Health study, led by Giorgio Quer, also found that ECG-CLIP better predicted future atrial fibrillation from ECGs displaying normal heart rhythms.
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New AI algorithm could improve detection and prediction of heart diseases - Scripps Research
Scripps Research scientists have developed an ECG foundation model that can be adapted to new clinical tasks with less labeled data.
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Scripps Research @scripps.edu · 02/09/2026
A new Nature Communications study from Jiang Zhu's lab reports a structure-guided strategy to stabilize influenza hemagglutinin (HA) trimers for nanoparticle vaccines. In preclinical models, the nanoparticles showed prolonged lymph node retention and elicited more robust immune responses.
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New design strategy expands nanoparticle vaccine approach to influenza viruses - Scripps Research
In our September 9 Front Row lecture, Giordano Lippi shares what his lab is learning about the role that tiny molecules called microRNAs play in brain development. With new insights, his team is developing novel tools for potentially treating genetic disorders of the developing brain. Take a seat an…
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Reposted by Scripps Research
Eric Topol @erictopol.bsky.social · 31/08/2026
On #LongCovid and profiling my colleague @julialmv.bsky.social @smithsonianmag.bsky.social www.smithsonianmag.com/innovation/m...
smithsonianmag.com
For Many Americans, Covid Is Still a Chronic, Disabling Disease. These Scientists Are Working Tirelessly to Bring Them Relief
Long Covid saps the strength and vitality of patients, who have little recourse to fight it. A team of specialists—including an afflicted researcher working mostly from her bed—is looking for answers
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Scripps Research @scripps.edu · 01/09/2026
💡 The Scripps Research Biotech Innovation Summit returns Oct. 22! Explore AI-enabled discovery, drug development and translation, with a keynote from Google Cloud CEO Thomas Kurian and Foresite Labs’ Jorge S. Reis-Filho. 🎟️ ow.ly/wsEu50ZGIao
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Scripps Research @scripps.edu · 31/08/2026
Chemists in shenvi.bsky.social's lab have developed an iron-catalyzed method that builds cis cyclopropanols one carbon at a time. Reported in Science Magazine, it is operationally simpler, uses accessible starting materials and tolerates common functional groups.
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Chemists develop simpler method to make molecular building block for drug development - Scripps Research
Scripps Research scientists used an inexpensive iron catalyst to assemble cyclopropanols one carbon at a time, giving chemists more flexible access to the functional group.
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Reposted by Scripps Research
UCLA Department of Chemistry & Biochemistry @uclacb.bsky.social · 28/08/2026
🎉 Exciting news from Prof. Abigail Doyle's group and collaborators!
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Scripps Research @scripps.edu · 28/08/2026
📣 In just one week, we’re going live from the Scripps Research NMR Core Facility! Tune in Friday, September 4, at 11 a.m. PT for a behind-the-scenes tour, meet the experts and bring your questions for a live Q&A. 📲 Be sure to set a reminder to watch LIVE here on YouTube: ow.ly/UKKm50ZzxvN
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Scripps Research @scripps.edu · 26/08/2026
Scripps Research, UCLA and #Sunthetics have received a $19.5M #NSF award to establish a nationally accessible, fully automated chemistry lab. The AI-enabled “Chemistry Node” will serve as a discovery engine and training tool for a new generation of chemists.
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Scripps Research and collaborators awarded $19.5 million to establish an open-access autonomous chemistry laboratory - Scripps Research
In our September 9 Front Row lecture, Giordano Lippi shares what his lab is learning about the role that tiny molecules called microRNAs play in brain development. With new insights, his team is developing novel tools for potentially treating genetic disorders of the developing brain. Take a seat an…
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Scripps Research @scripps.edu · 25/08/2026
After benefiting from the mentorship, rigorous training and professional connections he found at Scripps Research, alumnus Greg Tabor is paying it forward—helping today’s graduate students answer many of the same questions he once had.
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Paying It Forward: Greg Tabor on Giving Back to the Next Generation - Scripps Research
The relationships built during graduate school often continue to shape careers long after a degree is earned, creating a community of scientists who learn from one another across generations. For Scripps Research alumnus Greg Tabor, who earned his PhD in 2015, that sense of continuity has come full circle.
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Scripps Research @scripps.edu · 22/08/2026
Dr. Amy Lightner of Calibr-Skaggs, Scripps Research and Scripps Clinic discusses updated surgical guidelines for ulcerative colitis—including why some patients may need fewer colonoscopies, how surgery rates have fallen by half in a decade and what her lab is uncovering about new treatments.
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The new guidelines for ulcerative colitis mean fewer surgeries—and fewer colonoscopies - Scripps Research Magazine
Dr. Amy Lightner has spent her career moving between the operating room and the research lab, treating ulcerative colitis (UC) and other inflammatory bowel disease (IBD) patients as a surgeon while also searching for better treatments as a scientist.
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Scripps Research @scripps.edu · 21/08/2026
We got to see proteins “dancing” in Professor Dorothee Kern’s lab. 🧬💃 Using techniques like fast kinetics and NMR, her team studies how proteins move at the atomic level, revealing how these dynamics control function and inform the design of more selective drugs and enzymes.
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Scripps Research @scripps.edu · 20/08/2026
Asst. Prof. Tiantian Liu has received a five-year National Institute of Allergy and Infectious Diseases (NIAID) New Innovators Award from the NIH, with up to $2.76M to study how the immune system activates killer T cells—work that advances new strategies to prevent and treat infectious diseases.
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Scripps Research scientist to receive $2.76 million NIAID New Innovators Award - Scripps Research
The five-year award will support fundamental research on immune cell biology, which aims to advance therapeutic strategies that harness T cell responses to prevent and treat infectious diseases.
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Scripps Research @scripps.edu · 20/08/2026
Meet Calibr-Skaggs EVP Arnab Chatterjee, who advances medicines across diseases. His work includes MMV371, a long-acting injectable antimalarial in Phase 1 trials. Calibr-Skaggs was also recently awarded up to $5.1M by NIH to develop a long-acting therapy for HIV and HBV. #WorldMosquitoDay 🦟
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Scripps Research @scripps.edu · 19/08/2026
Nature produces molecules with extraordinary biological effects, but it doesn’t organize them for drug development. In Ryan Shenvi’s lab, chemists use synthesis and computation to rebuild and strategically redesign complex natural molecules to make them easier to study.
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Scripps Research @scripps.edu · 19/08/2026
Scripps Research established the Peter K. Vogt Endowed Chair, honoring the cancer research pioneer who contributed to the discovery of the first oncogene. Associate Professor Michael Erb, who develops chemical tools to target cancer-driving gene programs, is selected as the inaugural holder.
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Scripps Research establishes endowed chair honoring Peter K. Vogt, influential pioneer in cancer research - Scripps Research
Scripps Research has established the Peter K. Vogt Endowed Chair, a new faculty chair honoring the impactful scientific career of Peter K. Vogt, professor emeritus in the institute's Department of Molecular and Cellular Biology.
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Scripps Research @scripps.edu · 17/08/2026
Officially two weeks in! 🎉 Our incoming graduate students are settling into life on campus. We’re so excited to see the discoveries they’ll make during their time in the Scripps Research Graduate Program!
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