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Informes Jones Manoel - Farol Brasil @jones-manoel.bsky.social · 07/08/2025

Camaradas, nesse vídeo, dentre outras coisas, divulgo toda minha agenda de atividades dos próximos dias. Ajudem a circular ao máximo, por favor. youtu.be/1Bjj8FSh9Nw?...

youtu.be

Meta derrubou minhas redes sociais

YouTube video by Jones Manoel

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David Lingenfelter, PhD @dlingenfelter.bsky.social · 02/08/2025

Even mild or asymptomatic SARS-CoV-2 infections can leave a lasting imprint on the immune system—one that may resemble patterns seen in autoimmune diseases and chronic infections. This challenges the assumption that recovery from mild illness is complete. www.embopress.org/doi/full/10....

Here’s a structured summary of the main findings and insights from the article “A methylation clock model of mild SARS‐CoV‐2 infection provides insight into immune dysregulation” published in Molecular Systems Biology:
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🧬 Key Findings
1. Persistent Epigenetic Changes After Mild SARS-CoV-2 Infection
• Both asymptomatic and mildly symptomatic infections induce similar DNA methylation changes, even when gene expression returns to baseline.
• These methylation changes persist for months, resembling patterns seen in autoimmune and inflammatory diseases.
2. Methylation Clock Model
• Researchers developed a machine learning model using methylation data to:
o Distinguish between pre-, during-, and post-infection states.
o Accurately predict time since infection.
• The methylation clock revealed distinct temporal clusters of methylation changes, each associated with specific immune cell types and transcription factors.
3. Anti-Protective Epigenetic State
• Contrary to the concept of trained immunity, the post-infection methylation state was found to be anti-protective:
o Individuals with a pre-infection methylation pattern resembling the post-infection state had higher viral loads and worse outcomes.
o This state was not induced by BCG vaccination, suggesting it is distinct from known protective epigenetic responses.
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🔍 Comparative Insights
4. Overlap with Other Diseases
• The post-SARS-CoV-2 methylation signature showed significant overlap with:
o Systemic Lupus Erythematosus (SLE)
o Chronic infections (e.g., HIV, Hepatitis C)
• No significant overlap was found with asthma, allergies, or tuberculosis.
5. Age and Epigenetic Vulnerability
• The post-infection-like methylation state increased with age, suggesting cumulative immune challenges may predispose individuals to less effective viral suppression.
________________________________________
🧠 Conceptual Implications
6. Epigenetic Memory o…

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Camarote da República @camarotedacpi.bsky.social · 06/08/2025

🫢🤭 "Ces não sentem vergonha? Nenhuma?" Erika Hilton (PSOL-SP) debocha de um deputado bolsonarista com fita na boca na tarde de ontem na Câmara dos Deputados. - 📽 Acesso Erika Hilton via IG

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Karina Lima @karilimax.bsky.social · 05/08/2025

Com a erupção do vulcão Monte Lewotobi Laki-Laki na Indonésia, tem rolando desinformação sobre vulcões - e vinda de um perfil grande. Então acho importante falar sobre isso Os vulcões emitem muito CO2, logo, seriam mais responsáveis pelo aquecimento global do que o homem? Não!!!!! Vem entender 👇

Foto do vulcão Monte Lewotobi Laki-Laki na Indonésia.
Foto: Indonesia's Geological Agency / AFP

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Isaac Schrarstzhaupt @schrarstzhaupt.bsky.social · 05/08/2025

Se vocês virem alguém falando besteira sobre o vulcão soltar muito mais dióxido de carbono na atmosfera do que a ação humana, leiam esse fio da @karilimax.bsky.social pra entender como isso não faz sentido. E sigam ela, caso ainda não sigam!

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max🇵🇸 @mbrzz.bsky.social · 29/07/2025

Please help Dr Farahat and his family friends. Please donate to his campaign below and boost, every little bit makes such a difference!! tinyurl.com/SupportFarha...

tinyurl.com

Donate to Help Rebuild the Life of Dr. Farhat's Family, organized by Farhat's Family

In the heart of war-torn Gaza, where destruction and loss are a daily re… Farhat's Family needs your support for Help Rebuild the Life of Dr. Farhat's Family

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Jeff Nascimento @jnascim.info · 28/07/2025

Grande reportagem no #Fantástico sobre a fome em Gaza, com relatos de pessoas no terreno e de especialistas, incluindo o jornalista palestino Rami Abou Jamous e @thibautbruttin.bsky.social

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Raphaellakay @raphaellakay.bsky.social · 21/05/2025

Haneen @naeemafamily.bsky.social a 6 enfants : Naeema (22 ans), Mumen (17 ans), Abdul Rahman (14 ans) et les jumeaux Elias et Elan (9 ans) elle m'a écrit qu'elle se sent impuissante et dévastée car elle ne peut pas fournir un abri à ses enfants

gofundme.com

Donate to Support the Al mubasher Family's Journey to Safety, organized by Suzanne Barhoum

Hello dear friends, My name is Haneen Awad, a Palestinian from … Suzanne Barhoum needs your support for Support the Al mubasher Family's Journey to Safety

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Simusz @simusz.bsky.social · 21/05/2025

Help Haneen and her family, every little helps. Don’t allow Bluesky to shut down accounts of people from Gaza.

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Alexios Vrykolakas @alexvrykolakas.bsky.social · 22/05/2025

bsky.app/profile/naee...

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Raphaellakay @raphaellakay.bsky.social · 23/05/2025

hello @mommunism.bsky.social & @alexwinter.com please help Haneen by repost, her campaign is going slow and she needs donation for feeding her children + they're sleeping in the street, they have no tent

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🩷💛🩵🎃Rainboos and Shriekles🎃🩷💛🩵 @candiphoenixesa.bsky.social · 24/05/2025

Their campaign is here if you want you want to send some funds their way to help: bsky.app/profile/naee...

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Raphaellakay @raphaellakay.bsky.social · 25/05/2025

svp faites un don si vous pouvez repartagez leur post

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Raphaellakay @raphaellakay.bsky.social · 25/05/2025

je repartage la cagnotte de Haneen et sa famille, avec qui j'échange par message iels n'ont pas reçu beaucoup de dons et dorment dans la rue svp donnez si vous pouvez repartagez leur cagnotte

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Raphaellakay @raphaellakay.bsky.social · 27/05/2025

je repartage encore la cagnotte de Haneen et sa famille elle a reçu quelques dons ces derniers jours mais c'est trop peu pour trouver un abri et se nourrir (il faut prendre en compte les frais de transaction de gofundme) donnez si vous pouvez repartagez/commentez son post

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Raphaellakay @raphaellakay.bsky.social · 29/05/2025

Haneen est toujours dans la rue avec ses enfants et sans tente, ils ont juste des couvertures par terre pour dormir hier elle m'a écrit qu'il y avait des bombardements pas loin de là où elle est avec sa famille - l'endroit n'est pas sûr donnez si vous pouvez repartagez/commentez leur post

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おしん @oshinoshin.bsky.social · 31/05/2025

naeemaさん✨

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Raphaellakay @raphaellakay.bsky.social · 31/05/2025

je repartage la cagnotte de Haneen et de Naima donnez si vous pouvez repartagez leur post commentez leur post, c'est toujours encourageant pour les gens à Gaza de voir qu'iels ne parlent pas dans le vide

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Raphaellakay @raphaellakay.bsky.social · 03/06/2025

Naeema écrit : "Nous fuyons encore, en emportant nos enfants et nos souvenirs, nous ne savons pas où être en sécurité. À chaque fois nous disons "c'est la dernière fois" mais la guerre revient, de plus en plus rude. Nous sommes fatigués... nous ne voulons plus de mort – nous voulons juste vivre."

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mollie @mollietindle.bsky.social · 31/05/2025

If you can help Amal, Nasser, & their 2 young children, please do soon! Nasser needs more medical care & the children need food very desperately. Amal said the prices are becoming worse & worse. Amal is my age, but she’s being forced to endure the worst a human can imagine. I think of that often.

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mollie @mollietindle.bsky.social · 01/06/2025

Israel killed more Palestinians searching for food and aid over this weekend. Amal has lost so much already. If you can, please donate to help her husband get treatment and her children some food. 🖤💚❤️

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Astrid @astarte.bsky.social · 01/06/2025

💔 never ending barbarity. Amal needs a hand!

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Mellanie Fontes-Dutra @mellziland.bsky.social · 30/05/2025

E hoje foi noticiado um caso fatal de gripe aviária H5N1 em Camboja, um menino de 11 anos. "Até agora neste ano, o Camboja registrou quatro casos humanos de gripe aviária H5N1, todos fatais" cidrap.umn.edu/avian-influe... apnews.com/article/camb....

cidrap.umn.edu

HHS cancels funding for Moderna’s candidate H5 avian flu and pandemic vaccines

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Mellanie Fontes-Dutra @mellziland.bsky.social · 30/05/2025

A Moderna mostrou resultados clínicos (fase 1/2) iniciais positivos da sua vacina ATUALIZADA contra GRIPE AVIÁRIA. E a administração dos EUA CANCELOU os investimentos nessa pesquisa Agora imagine se ocorre um surto entre huamnos desse vírus cuja letalidade estima-se em 51%

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Ryan Marino, MD @ryanmarino.bsky.social · 28/05/2025

COVID infection in pregnancy is associated with DOUBLE the rate of stillbirths because the SARS-CoV-2 virus damages the placenta

apnews.com

Coronavirus can destroy the placenta and lead to stillbirths

New research suggests the coronavirus can invade and destroy the placenta and lead to stillbirths in infected women.

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Fábio @dozzademiranda.bsky.social · 27/05/2025

3 anos de pandemia não foram suficiente parar incutir higiene no Povo. Salas de aula lotadas, com janelas e portas fechadas (independente de estarem com ar condicionado ligado).

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Pato 🦆 @donpatito.bsky.social · 28/05/2025

Minas decretou hoje situação de emergência sanitária animal em razão de casos confirmados em uma fazenda em Mateus Leme, na Região Metropolitana de Belo Horizonte. 😥 bsky.app/profile/esta...

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Mellanie Fontes-Dutra @mellziland.bsky.social · 27/05/2025

Quase 1 da manhã e fiz uma aula sobre gripe aviária H5N1, pegando desde os anos 90 pra cá É isso amigos, indo dormir preocupada

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Diário do Centro do Mundo @dcmonline.bsky.social · 28/05/2025

Governo Trump anuncia sanções que podem afetar Moraes e ministros do STF; entenda www.diariodocentrodomundo.com.br/governo-trum...

diariodocentrodomundo.com.br

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