Reposted by Pavel MoudrýHana Polasek-Sedlackova @hanasedlackova.bsky.social · 06/08/2026📢 We are looking for a PhD student to join our lab! Explore how DNA replication is regulated during development and disease using quantitative cell biology, advanced microscopy, CRISPR engineering, and AI tools. 👉 Full details: www.ibp.cz/en/for-publi... Thank you for sharing! 🔬 065
Pavel Moudrý @3reak.bsky.social · 26/06/2026Join us for the scanR User Meeting + Advanced Training 2026 in Prague, 21–23 Sept 2026. User talks, scientific exchange, hands-on scanR training, AI-assisted image analysis, TruAI workflows and custom AI model training. Info & registration: course.img.cas.cz/scanr/ 002
Reposted by Pavel MoudrýBartek Lab @barteklab.bsky.social · 16/06/2026ERC CZ funded postdoctoral opportunity in Olomouc, Czechia: www.linkedin.com/posts/proteo...linkedin.comProteotoxic stress | Proteotoxic stress OlomoucThe Proteotoxic stress group at IMTM Olomouc is looking for a talented Postdoc to join our ERC CZ-funded project for 2 years. If you want to work on a pioneering platform focused on subcellular microt... 001
Reposted by Pavel MoudrýHana Polasek-Sedlackova @hanasedlackova.bsky.social · 14/11/2025Truly delighted to host @agagambus.bsky.social next week in Brno for an IBP Guest Lecture! Her groundbreaking work and genuinely human approach to science have always been a great inspiration to me. Come and join us for her lecture at IBP 👇 1101
Reposted by Pavel MoudrýCommunications Biology @commsbio.nature.com · 06/11/2025A mini review explores the molecular drivers of replication fork acceleration and their consequences for genome stability, innate immunity, and cancer. @3reak.bsky.social www.nature.com/articles/s42...nature.comThe need for speed: drivers and consequences of accelerated replication forks - Communications BiologyA mini review explores molecular drivers of replication fork acceleration and their consequences for genome stability, innate immunity, and cancer. 011
Reposted by Pavel Moudrýstapleslab.bsky.social @stapleslab.bsky.social · 22/10/2025New preprint from the lab for any DNA repair or replication stress geeks out there! www.biorxiv.org/content/10.1...biorxiv.orgA nuclease-driven mechanism of post-replicative ssDNA gap suppression.The persistence of post-replicative ssDNA gaps following PRIMPOL-mediated replication repriming is linked to chemosensitivity, and in all models reported to date the nuclease MRE11 has been implicated... 3216
Reposted by Pavel MoudrýAndrew Blackford @andrewblackford.bsky.social · 29/05/2025We’re #hiring, please share! A fully funded #postdoc position is available in my lab to work on DNA damage response mechanisms. Please get in touch with your CV if you are interested; closing date: 27th June 2025. More details here: candidate.hr-manager.net/ApplicationI...candidate.hr-manager.netPostdoctoral Research Associate in the Blackford GroupA position as Postdoctoral Research Associate is available at the Department of Cellular and Molecular Medicine, in the group headed by Dr. Andrew Blackford. Th 02335
Reposted by Pavel Moudrýaltmeyerlab @altmeyerlab.bsky.social · 21/05/2025Sharing our latest work tracking DNA damage inheritance by Live+QIBC www.nature.com/articles/s41.... Huge congrats to @apanagopoulos.bsky.social, M. Stout and all co-authors for this tour de force! Beautifully summarized by @s-j-aitken.bsky.social & E. Reilly www.nature.com/articles/d41... 04311
Pavel Moudrý @3reak.bsky.social · 15/04/2025🧬 Zbývá už jen poslední měsíc na přihlášení na PhD pozici zaměřenou na výzkum replikace DNA. Přidej se k našemu týmu a podílej se na špičkovém biomedicínském výzkumu! 📍Ústav Molekulární a Translační Medicíny, UPOL Olomouc 📅 Deadline: 15.5.2025 www.researchjobs.cz/job/phd-pozi...researchjobs.czPhD pozice ve výzkumu replikace DNAVe výzkumné skupině DNA replication dynamics na Ústavu molekulární a translační medicíny Lékařské fakulty Univerzity Palackého v Olomouci nabízíme pozici pro PhD studenta. Disertační práce na téma … 012
Pavel Moudrý @3reak.bsky.social · 30/03/2025Our new preprint is now on bioRxiv! 📄 We introduce qAID, an AI-based workflow for automated analysis of DNA replication dynamics. Glad to have contributed a small part to this study. 033
Reposted by Pavel MoudrýHana Polasek-Sedlackova @hanasedlackova.bsky.social · 30/03/2025📢 For all DNA fiber enthusiasts! 🟥🟩 We are thrilled to announce the release of our long-awaited AI-based workflow for the automated and quantitative analysis of DNA fibers. It's an exciting step forward—check it out on bioRxiv! lnkd.in/dQWUPtsP 62921
Reposted by Pavel MoudrýKumar Somyajit & Lab @ksomyajit.bsky.social · 20/03/2025Thrilled to share our lab's first preprint, led by an exceptional PhD student Gita Chhetri and with the support of wonderful collaborators, we find that replisome function is rate-limited by strand-specific PCNA dynamics. Hope you will enjoy reading. www.biorxiv.org/content/10.1... Brief teaser:biorxiv.orgPAF15-PCNA assembly exhaustion governs lagging strand replication and replisome integrityGenome replication in eukaryotic cells is surveyed by the S-phase checkpoint, which orchestrates sequential replication origin activation to avoid exhaustion of hitherto poorly defined rate-limiting r... 33821
Reposted by Pavel MoudrýLori Passmore @lapassmore.bsky.social · 02/03/2025For all of you who cannot access pubmed, here is a good alternative: europepmc.orgeuropepmc.orgEurope PMCHome - Europe PMCEurope PMC is an archive of life sciences journal literature. 822584