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Pavel Moudrý

@3reak.bsky.social
70 followers 125 following 3 posts

Group leader at Institute of Molecular and Translational Medicine, Palacký University Olomouc Former postdoc @barteklab.bsky.social. My group explores DNA replication dynamics in response to PARP inhibitors.

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Reposted by Pavel Moudrý
Hana Polasek-Sedlackova @hanasedlackova.bsky.social · 06/08/2026
📢 We are looking for a PhD student to join our lab! Explore how DNA replication is regulated during development and disease using quantitative cell biology, advanced microscopy, CRISPR engineering, and AI tools. 👉 Full details: www.ibp.cz/en/for-publi... Thank you for sharing! 🔬
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Pavel Moudrý @3reak.bsky.social · 26/06/2026
Join us for the scanR User Meeting + Advanced Training 2026 in Prague, 21–23 Sept 2026. User talks, scientific exchange, hands-on scanR training, AI-assisted image analysis, TruAI workflows and custom AI model training. Info & registration: course.img.cas.cz/scanr/
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Reposted by Pavel Moudrý
Bartek Lab @barteklab.bsky.social · 16/06/2026
ERC CZ funded postdoctoral opportunity in Olomouc, Czechia: www.linkedin.com/posts/proteo...
linkedin.com
Proteotoxic stress | Proteotoxic stress Olomouc
The Proteotoxic stress group at IMTM Olomouc is looking for a talented Postdoc to join our ERC CZ-funded project for 2 years. If you want to work on a pioneering platform focused on subcellular microt...
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Reposted by Pavel Moudrý
Hana Polasek-Sedlackova @hanasedlackova.bsky.social · 14/11/2025
Truly delighted to host @agagambus.bsky.social next week in Brno for an IBP Guest Lecture! Her groundbreaking work and genuinely human approach to science have always been a great inspiration to me. Come and join us for her lecture at IBP 👇
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Reposted by Pavel Moudrý
Communications Biology @commsbio.nature.com · 06/11/2025
A mini review explores the molecular drivers of replication fork acceleration and their consequences for genome stability, innate immunity, and cancer. @3reak.bsky.social www.nature.com/articles/s42...
nature.com
The need for speed: drivers and consequences of accelerated replication forks - Communications Biology
A mini review explores molecular drivers of replication fork acceleration and their consequences for genome stability, innate immunity, and cancer.
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Reposted by Pavel Moudrý
stapleslab.bsky.social @stapleslab.bsky.social · 22/10/2025
New preprint from the lab for any DNA repair or replication stress geeks out there! www.biorxiv.org/content/10.1...
biorxiv.org
A nuclease-driven mechanism of post-replicative ssDNA gap suppression.
The persistence of post-replicative ssDNA gaps following PRIMPOL-mediated replication repriming is linked to chemosensitivity, and in all models reported to date the nuclease MRE11 has been implicated...
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Reposted by Pavel Moudrý
Andrew Blackford @andrewblackford.bsky.social · 29/05/2025
We’re #hiring, please share! A fully funded #postdoc position is available in my lab to work on DNA damage response mechanisms. Please get in touch with your CV if you are interested; closing date: 27th June 2025. More details here: candidate.hr-manager.net/ApplicationI...
candidate.hr-manager.net
Postdoctoral Research Associate in the Blackford Group
A position as Postdoctoral Research Associate is available at the Department of Cellular and Molecular Medicine, in the group headed by Dr. Andrew Blackford. Th
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Reposted by Pavel Moudrý
altmeyerlab @altmeyerlab.bsky.social · 21/05/2025
Sharing our latest work tracking DNA damage inheritance by Live+QIBC www.nature.com/articles/s41.... Huge congrats to @apanagopoulos.bsky.social, M. Stout and all co-authors for this tour de force! Beautifully summarized by @s-j-aitken.bsky.social & E. Reilly www.nature.com/articles/d41...
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Pavel Moudrý @3reak.bsky.social · 15/04/2025
🧬 Zbývá už jen poslední měsíc na přihlášení na PhD pozici zaměřenou na výzkum replikace DNA. Přidej se k našemu týmu a podílej se na špičkovém biomedicínském výzkumu! 📍Ústav Molekulární a Translační Medicíny, UPOL Olomouc 📅 Deadline: 15.5.2025 www.researchjobs.cz/job/phd-pozi...
researchjobs.cz
PhD pozice ve výzkumu replikace DNA
Ve výzkumné skupině DNA replication dynamics na Ústavu molekulární a translační medicíny Lékařské fakulty Univerzity Palackého v Olomouci nabízíme pozici pro PhD studenta. Disertační práce na téma …
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Pavel Moudrý @3reak.bsky.social · 30/03/2025
Our new preprint is now on bioRxiv! 📄 We introduce qAID, an AI-based workflow for automated analysis of DNA replication dynamics. Glad to have contributed a small part to this study.
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Reposted by Pavel Moudrý
Hana Polasek-Sedlackova @hanasedlackova.bsky.social · 30/03/2025
📢 For all DNA fiber enthusiasts! 🟥🟩 We are thrilled to announce the release of our long-awaited AI-based workflow for the automated and quantitative analysis of DNA fibers. It's an exciting step forward—check it out on bioRxiv! lnkd.in/dQWUPtsP
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Reposted by Pavel Moudrý
Kumar Somyajit & Lab @ksomyajit.bsky.social · 20/03/2025
Thrilled to share our lab's first preprint, led by an exceptional PhD student Gita Chhetri and with the support of wonderful collaborators, we find that replisome function is rate-limited by strand-specific PCNA dynamics. Hope you will enjoy reading. www.biorxiv.org/content/10.1... Brief teaser:
biorxiv.org
PAF15-PCNA assembly exhaustion governs lagging strand replication and replisome integrity
Genome replication in eukaryotic cells is surveyed by the S-phase checkpoint, which orchestrates sequential replication origin activation to avoid exhaustion of hitherto poorly defined rate-limiting r...
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Reposted by Pavel Moudrý
Lori Passmore @lapassmore.bsky.social · 02/03/2025
For all of you who cannot access pubmed, here is a good alternative: europepmc.org
europepmc.org
Europe PMCHome - Europe PMC
Europe PMC is an archive of life sciences journal literature.
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