Excited to share our latest work—establishing a pipeline for DNA methylation–based CNS tumor diagnostics from minimally invasive CSF liquid biopsies—published today in Nature Cancer! Huge thanks to all collaborators. www.nature.com/articles/s43... #LiquidBiopsy #PediatricNeuroOncology #TeamScience
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M-PACT leverages cell-free DNA methylomes to achieve robust classification of pediatric brain tumors - Nature Cancer
Smith et al. present M-PACT, a deep neural network leveraging low-input cell-free DNA methylation profiles to achieve robust classification of pediatric brain tumors and enable cellular deconvolution ...