Rishi De-Kayne @rishidekayne.bsky.social · 05/02/2026Bioprospecting has given us incredible discoveries, from life-saving drugs to agricultural innovations. But traditional approaches rely heavily on serendipity and are hard to scale. [2/8] 110 0
Rishi De-Kayne @rishidekayne.bsky.social · 05/02/2026In silico bioprospecting tries to fix this by mining existing databases. But those databases are taxonomically biased (see another one of our pubs dropping today: thestacks.org/publications...), and the methods often require knowing what you're looking for upfront. [3/8]thestacks.orgBiology needs to become prospectiveSince biological data are often non-independent, more data doesn't always mean more insight. We argue that a prospective approach is needed to uncover the deepest principles of life. 110 0
Rishi De-Kayne @rishidekayne.bsky.social · 05/02/2026We propose an evolution-integrated framework that combines the best of both worlds: expanding sampling breadth while more deeply interrogating existing data through an evolutionary lens. [4/8] 110 0
