iiinova — where your digital self keeps evolving

Replies

Rishi De-Kayne @rishidekayne.bsky.social · 05/02/2026

Really excited to share my first pub from my work at @arcadiascience.com - Strategizing the search for bio-utility: A framework for evolution-integrated in silico bioprospecting thestacks.org/publications... [1/8] 🧵

thestacks.org

Strategizing the search for bio-utility: A framework for evolution-integrated in silico bioprospecting

To accurately and efficiently identify instances of useful biological variation, we must establish an evolution-integrated bioprospecting framework. This will enable us to better interpret biological ...

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Rishi De-Kayne @rishidekayne.bsky.social · 05/02/2026

Bioprospecting has given us incredible discoveries, from life-saving drugs to agricultural innovations. But traditional approaches rely heavily on serendipity and are hard to scale. [2/8]

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Rishi De-Kayne @rishidekayne.bsky.social · 05/02/2026

In silico bioprospecting tries to fix this by mining existing databases. But those databases are taxonomically biased (see another one of our pubs dropping today: thestacks.org/publications...), and the methods often require knowing what you're looking for upfront. [3/8]

thestacks.org

Biology needs to become prospective

Since biological data are often non-independent, more data doesn't always mean more insight. We argue that a prospective approach is needed to uncover the deepest principles of life.

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