ME/CFS Science @mecfsscience.org · 06/05/20264) The second possibility is that there is one biological process that has vulnerabilities at those particular ages. For example, the peaks might correspond to hormonal changes (puberty and peri-menopause). 1170
ME/CFS Science @mecfsscience.org · 06/05/20265) They are confident the bimodal onset pattern exists because they found it in multiple data sources: the Norwegian healthcare data, the European survey and the DecodeME study. These have different biases, yet the pattern remained the same. 2150
ME/CFS Science @mecfsscience.org · 06/05/20266) Interestingly, there wasn't a big difference between men and women in the onset pattern. If it were hormonal changes for example, we would expect to find a sex difference as well but that wasn’t the case. 2170
Wilhelmina Jenkins @wilhelminaj.bsky.social · 06/05/2026The bimodal pattern has been shown to be true here in the US too. I can’t remember right now how to locate the reference, but @exceedhergrasp1.bsky.social would know. 150