ME/CFS Science @mecfsscience.org · 06/05/20263) One is that there are two different paths leading to ME/CFS, one for the early onset in late teens, and a different path for the second onset in your mid 30s. So, two different disease that look the same but are different under the hood. 1160
ME/CFS Science @mecfsscience.org · 06/05/20264) The second possibility is that there is one biological process that has vulnerabilities at those particular ages. For example, the peaks might correspond to hormonal changes (puberty and peri-menopause). 1170
ME/CFS Science @mecfsscience.org · 06/05/20265) They are confident the bimodal onset pattern exists because they found it in multiple data sources: the Norwegian healthcare data, the European survey and the DecodeME study. These have different biases, yet the pattern remained the same. 2150
