ME/CFS Science @mecfsscience.org · 18/10/20253) Peterson and his team managed to create zebrafish larvae where the gene ACOD1is overexpressed. They then did several behavioural experiments in fish with and without the gene change. 170
ME/CFS Science @mecfsscience.org · 18/10/20254) In tests with lights or vibration as stimuli being turned on and off, the zebrafish with ACOD1 overexpression had approximately a 40% reduction in movement compared to controls. They also had reduced oxygen consumption. 160
ME/CFS Science @mecfsscience.org · 18/10/20255) The gene expression was regulated using heat-shock so the researchers could test different versions of ACOD1 overexpression by increasing the temperature of the water. The more the gene was expressed, the greater the signs of energy deficits. 160
