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Journal of Clinical Investigation @jci.org · 04/08/2026

How do high-risk APOL1 variants lead to kidney transplant rejection? doi.org/10.1172/JCI1... Madhav C Menon & team @yaleschoolofmed.bsky.social discover that APOL1 variants promote CD8 T-cell activation via Ca2+ signaling, causally explaining their link to kidney rejection. @the-asci.org

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Journal of Clinical Investigation @jci.org · 04/08/2026

Behind the scenes: Celebrating with Team Menon lab: From right to left, Dr Madhav C Menon (corresponding author), Gabriel C Barsotti, John F Pell (First author), EM Tanvir (co-first author) and Anand C Reghuvaran. And first author John Pell in the Lab.

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