Jeff Browndyke @jeffbrowndyke.bsky.social · 25/04/2026The push for serum blood (or CSF) tests for a condition that is still terminal, for which we don't have great treatment options, is a 'feeder mechanism' for the anti-amyloid infusion therapies. Make no mistake, the infusion therapies do disease-modify and clear out amyloid plaque, but... 2/n 120
Jeff Browndyke @jeffbrowndyke.bsky.social · 25/04/2026...the infusion therapies DO NOT reverse the Alzheimer's disease dementia process in those already showing even mild symptoms (i.e., all the people currently being direct marketed to like gangbusters on TV and online). www.cochrane.org/about-us/new... 3/ncochrane.orgAnti-amyloid Alzheimer’s drugs show no clinically meaningful effect | Cochrane 132
Jeff Browndyke @jeffbrowndyke.bsky.social · 25/04/2026The infusion therapies merely slow down the decline process, just like the symptomatic AD medication we had before (e.g., donepezil), but they do so at a far greater cost than the GI side-effects from the symptomatic medications. The new infusion therapies risk stroke and brain swelling. 4/n 110