Reposted by Yuval Shapir Itai
We are excited to share our new study @cp-cancercell.bsky.social identifying Zeb2 as a master genetic switch controlling the tumor-associated macrophage (TAM) program. Led by Fadi Sheban, Truong San Phan, Kai Kun Xie & @florianingelfinger.bsky.social. (1/20)
www.cell.com/cancer-cell/...
cell.com
ZEB2 is a master switch controlling the tumor-associated macrophage program
Sheban et al. present a single-cell CRISPR screen to dissect macrophage gene regulation
in a pan-cancer tumor-associated macrophage (TAM) atlas. Using a generative model,
they identify ZEB2 as a key d...