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Reposted by @yannphd.bsky.social

Harvard Molecular Metabolism @met-hsph.bsky.social · 03/09/2026

New study in Nature Communications from the Manning lab shows that dietary protein is a dominant signal activating the nutrient-sensing mTORC1 pathway in the liver after feeding in mice and determines how strongly this response depends on insulin signaling. www.nature.com/articles/s41...

nature.com

Dietary protein governs the role of insulin signaling in the postprandial regulation of hepatic mTORC1 - Nature Communications

The nutrient-sensing kinase complex mTORC1 regulates metabolism, yet the physiological signals controlling its activity in the liver are incompletely defined. Here, the authors show that dietary prote...

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