Sign in

Rendong Yang

@yang-lab.bsky.social
25 followers 36 following 3 posts

Interested in algorithms, genomics, bioinformatics and prostate cancer research. Associate Professor at the Department of Urology, Northwestern University.

PostsRepliesMedia
Rendong Yang @yang-lab.bsky.social · 20/03/2026
Excited to share our latest work @natcomms.nature.com ! We uncover how tumor-specific lncRNA IGF1R-AS1 trans-regulates chromatin interactions to drive oncogenic MYC signaling. A new layer of MYC regulation in prostate cancer. @pcf-science.bsky.social www.nature.com/articles/s41...
nature.com
Tumor-specific lncRNA IGF1R-AS1 trans-regulates chromatin interactions associated with oncogenic MYC signaling - Nature Communications
The role of long non-coding RNAs (lncRNAs) in regulating cancer progression remains to be explored. Here, the authors identify an antisense lncRNA in the IGF1R locus (IGF1RAS1) which strongly interact...
010
Rendong Yang @yang-lab.bsky.social · 20/01/2026
Thrilled to share our new @natcomms.nature.com paper! We introduce a genomic language model that detects and corrects a key chimera artifact in Nanopore direct RNA sequencing—improving isoform and chimeric transcript discovery. 🔗 www.nature.com/articles/s41... @luriecancer.bsky.social #LLM #AI
nature.com
Genomic language model mitigates chimera artifacts in nanopore direct RNA sequencing - Nature Communications
Direct RNA sequencing suffers from chimera artifact contamination. Here, the authors develop DeepChopper, a genomic language model that detects artifacts with high accuracy, enabling more reliable tra...
041
Rendong Yang @yang-lab.bsky.social · 10/04/2025
Thrilled to share our new study in @ScienceAdvances Androgen receptor–regulated lncRNA PRCAT71 promotes AR signaling through the interaction with KHSRP in prostate cancer | Science Advances www.science.org/doi/10.1126/... @pcf-science.bsky.social #lncRNA #ARsignaling #CancerResearch
science.org
Androgen receptor–regulated lncRNA PRCAT71 promotes AR signaling through the interaction with KHSRP in prostate cancer
Long noncoding RNA PRCAT71 and RNA binding protein KHSRP stabilize androgen receptor mRNA to promote prostate cancer progression.
021