Excited to share our latest work @natcomms.nature.com !
We uncover how tumor-specific lncRNA IGF1R-AS1 trans-regulates chromatin interactions to drive oncogenic MYC signaling.
A new layer of MYC regulation in prostate cancer. @pcf-science.bsky.social
www.nature.com/articles/s41...
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Tumor-specific lncRNA IGF1R-AS1 trans-regulates chromatin interactions associated with oncogenic MYC signaling - Nature Communications
The role of long non-coding RNAs (lncRNAs) in regulating cancer progression remains to be explored. Here, the authors identify an antisense lncRNA in the IGF1R locus (IGF1RAS1) which strongly interact...