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Wen Xue

@xueumass.bsky.social
4 followers 3 following 0 posts

RNA Biologist and Cancer Researcher @ UMass Chan Medical School, RNA Therapeutics Institute

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Reposted by Wen Xue
Erik Sontheimer 🇺🇸💙🇺🇦 @eriksontheimer.bsky.social · 29/04/2026
Site-specific, multi-kilobase insertions and over-writes in mammalian cells, without DSBs, HDR, recombinases, integrases, transposases, or active cell cycling? Using fully or predominantly single-stranded DNA donors? 1/15
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Reposted by Wen Xue
RNA Therapeutics Institute @rti-umasschan.bsky.social · 29/04/2026
📰 Hot off the press from the Xue & Sontheimer labs 🧬: Prime assembly enables precise genomic insertions up to 11 kb in cells, providing a universal strategy to correct many pathogenic mutations within a gene. Read it @nature.com: buff.ly/dYn0NjS @UMassChan.bsky.social @eriksontheimer.bsky.social
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