Reposted by Erik Sontheimer 🇺🇸💙🇺🇦Keystone Symposia @keystonesymposia.bsky.social · 30/09/2026🧬 Our joint meeting Precision Genome Engineering + Targeted Delivery of Nucleic Acid Medicines (Jan 25–28, Keystone) cover genome editing, delivery innovations & clinical translation. Short talk abstracts + $1500 scholarships close TOMORROW (Oct 1). Apply now: hubs.la/Q04xVtQN0 hubs.la/Q04xVv0z0 022
Erik Sontheimer 🇺🇸💙🇺🇦 @eriksontheimer.bsky.social · 30/09/2026The deadline for short talks is almost here — get your abstracts in and join our great line-up! #KSGenomeEng27 www.keystonesymposia.org/conferences/...keystonesymposia.orgPrecision Genome Engineering: From Laboratory to Clinic | Keystone SymposiaJoin us at the Keystone Symposia on Precision Genome Engineering: From Laboratory to Clinic, January 2027, in Keystone, with field leaders! 010
Erik Sontheimer 🇺🇸💙🇺🇦 @eriksontheimer.bsky.social · 30/08/2026Go Carleigh! www.bostonglobe.com/2026/08/30/m...bostonglobe.comCan a progressive overtake two center-left Democrats in N.H.’s 1st Congressional District race? - The Boston GlobeWhile the establishment-backed top contenders, Stefany Shaheen and Maura Sullivan, are locked in a close contest, a progressive push by Carleigh Beriont may be gaining momentum. 001
Reposted by Erik Sontheimer 🇺🇸💙🇺🇦RNA Therapeutics Institute @rti-umasschan.bsky.social · 29/04/2026📰 Hot off the press from the Xue & Sontheimer labs 🧬: Prime assembly enables precise genomic insertions up to 11 kb in cells, providing a universal strategy to correct many pathogenic mutations within a gene. Read it @nature.com: buff.ly/dYn0NjS @UMassChan.bsky.social @eriksontheimer.bsky.social 034
Erik Sontheimer 🇺🇸💙🇺🇦 @eriksontheimer.bsky.social · 29/04/2026Site-specific, multi-kilobase insertions and over-writes in mammalian cells, without DSBs, HDR, recombinases, integrases, transposases, or active cell cycling? Using fully or predominantly single-stranded DNA donors? 1/15 14926
Reposted by Erik Sontheimer 🇺🇸💙🇺🇦NPR @npr.org · 01/03/2026For the 2026 primary elections, NPR has collected deadlines and information on how to register to vote — online, in person or by mail — in every U.S. state and territory.n.prHow to register to vote and check your registration statusFor the 2026 primary elections, NPR has collected deadlines and information on how to register to vote — online, in person or by mail — in every U.S. state and territory. 4123791623
Reposted by Erik Sontheimer 🇺🇸💙🇺🇦CRISPR 2026 @crisprmeeting.bsky.social · 02/02/2026Registration for CRISPR 2026 is now open: web.cvent.com/event/ac20b6.... Early-bird price discounts are available until the end of February.web.cvent.comPersonal Information - CRISPR2026 124
Reposted by Erik Sontheimer 🇺🇸💙🇺🇦CRISPR 2026 @crisprmeeting.bsky.social · 23/01/2026The CRISPR 2026 website is up! Links for abstract submission and registration will be available February 1st: web.cvent.com/event/ac20b6...web.cvent.comCRISPR2026. 043
Reposted by Erik Sontheimer 🇺🇸💙🇺🇦Steven Mazie @stevenmazie.bsky.social · 08/09/2025SCOTUS: considering race as one factor in a college applicant's file is blatantly unconstitutional ALSO SCOTUS: considering race as one factor in targeting whom to detain and deport is cool cool cool 200144045742
Reposted by Erik Sontheimer 🇺🇸💙🇺🇦RNA Therapeutics Institute @rti-umasschan.bsky.social · 01/08/2025Hot off the press from the RTI: Prime assembly with linear DNA donors enables large genomic insertions pubmed.ncbi.nlm.nih.gov/40667017/?ut... #RNA #RNATherapeuticspubmed.ncbi.nlm.nih.govPrime assembly with linear DNA donors enables large genomic insertions - PubMedTargeted insertion of large DNA fragments has promising applications for genome engineering and gene therapy<sup>1,2</sup>. Twin prime editing (PE) guide RNAs (pegRNAs) have enabled relatively large insertions,... 011
Reposted by Erik Sontheimer 🇺🇸💙🇺🇦Franklin Nobrega @fnobrega.bsky.social · 28/07/2025Thrilled to see our Kiwa story out today! A membrane-associated supercomplex that senses infection and blocks replication and transcription. www.cell.com/cell/fulltex... Huge congratulations to Yi and Zhiying for bringing it home, to Thomas for starting us off, and to all the collaborators.cell.comKiwa is a membrane-embedded defense supercomplex activated at phage attachment sitesZhang, Todeschini, and Wu et al. show that the bacterial defense system Kiwa senses phage attachment at the membrane and assembles a transmembrane complex that halts infection by blocking phage DNA re... 1011850
Reposted by Erik Sontheimer 🇺🇸💙🇺🇦Leo Schärfen @leoschaerfen.bsky.social · 22/07/2025Fun news: I'm starting my research group at @rti-umasschan.bsky.social as the inaugural Maraganore Fellow! Our lab will focus on the RNA sequence-structure-function relationship in the cellular environment. Visit our website to explore open positions: schaerfenlab.com #RNA #Hiring #PostbacJobs 1103
Reposted by Erik Sontheimer 🇺🇸💙🇺🇦UMass Chan Medical School @umasschan.bsky.social · 16/05/2025On Thursday, Anastasia Khvorova, PhD, received the 2025 Else Kröner Fresenius Prize for Medical Research, a $2.7 million award, for her pioneering work in the field of RNA-based therapies. 📸: Else Kröner-Fresenius-Stiftung #EKFprize25 #EKFS #RNA @ekfstiftung.bsky.social @rti-umasschan.bsky.social 175
Reposted by Erik Sontheimer 🇺🇸💙🇺🇦Alt NIH Bluesky 🧪 @altnih4science.bsky.social · 28/03/2025"The consolidation/RIF plan pulls power away from scientists and puts it in the hands of political employees. It sets up Trump and Musk to kill NIH as an evidence-based science funder. We must stop this plan." New contributed post on our blog: Please read. It describes Orban and authoritarianism. 🧪open.substack.comThe NIH firing plan is really a radical institute merger and an authoritarian takeoverthis is an Orbanization of US science: a move to exert political control over discovery, which will kill the US medical research industry and end cancer cures. The plan must be stopped. We can act. 6230107
Erik Sontheimer 🇺🇸💙🇺🇦 @eriksontheimer.bsky.social · 22/11/2024Pressing question of the day: when will @epigenetichulk start smashing puny genomes on Bluesky? 150