Xiaoxu Yang @xiaoxuyang.bsky.social · 21/05/2026github.com/XiaoxuYangLab/DeepMosaic/releases/tag/v1.2.0 DeepMosaic v1.2.0 is now released. It enables custom genome build for donor-specific genome or non-human diploid organism. Additional changes and updates are documented in the release note. Many thanks to Sai and our user community!github.comRelease 05-21-2026 v1.2.0 release · XiaoxuYangLab/DeepMosaicDeepMosaic v1.2.0 release notes: Major updates: Based on user request, DeepMosaic now supports custom genome build support, which allows for donor-specific genome assembly as well as non-human di... 000
Reposted by Xiaoxu YangJulie Kiefer @julieckiefer.bsky.social · 15/04/2026Congratulations to @xiaoxuyang.bsky.social @uuhsresearch.bsky.social on his team's seminal discovery in collaboration with colleagues @ucsdhealthsci.bsky.social and published in @nature.com! How Early Nerve Cell Choices Shape the Peripheral Nervous System healthcare.utah.edu/newsroom/new...healthcare.utah.eduUnlocking Secrets of Human Development: How Early Nerve Cell Choices Shape the Peripheral Nervous SystemBy examining genetic clues that linger in adult cells, scientists have now gained surprising insights into the developmental origins of the nerves outside the brain and spine. 021
Xiaoxu Yang @xiaoxuyang.bsky.social · 15/04/2026Unlocking Secrets of Human Development: How Early Nerve Cell Choices Shape the Peripheral Nervous System healthcare.utah.edu/newsroom/new...healthcare.utah.eduUnlocking Secrets of Human Development: How Early Nerve Cell Choices Shape the Peripheral Nervous SystemBy examining genetic clues that linger in adult cells, scientists have now gained surprising insights into the developmental origins of the nerves outside the brain and spine. 000
Reposted by Xiaoxu YangNature @nature.com · 02/04/2026Nature research paper: Developmental organization of sensory and sympathetic ganglia go.nature.com/3Qdz2HPgo.nature.comDevelopmental organization of sensory and sympathetic ganglia - NatureFindings suggest that neural crest fate bias predominantly emerges within the neural tube, and that only a minor subset of delaminated progenitors retain multipotency to generate both sensory and sympathetic derivatives. 0154
Xiaoxu Yang @xiaoxuyang.bsky.social · 01/04/2026In a study published today in Nature (rdcu.be/fbf5Q), we described the developmental organization of sensory and sympathetic ganglia in multiple organisms. Huge thanks to the great contribution from @gleesonlab.bsky.social , Keng Ioi (Harry) Vong, @melaniedwhite.bsky.social, and all collaborators! 031
Reposted by Xiaoxu YangQi Chen @qichen-lab.bsky.social · 20/01/2026Perhaps the most puzzling part: We see a paradox: the rsRNA length shift is progressive⏳yet the global RNA profile shows an "Aging Cliff"📉. Cliff or Progression? Maybe the gradual shift is the forerunner—accumulating silently until it triggers the cliff. bsky.app/profile/qich... 074
Xiaoxu Yang @xiaoxuyang.bsky.social · 10/06/2025Our special issue "Genomic Mosaicism in Human Development and Diseases" on Genes www.mdpi.com/2073-4425/16... is officially out! Thank you all authors for your contributions! Thanks, Xincen, for writing the editorial with me.mdpi.com 020
Xiaoxu Yang @xiaoxuyang.bsky.social · 08/01/2025 • The cis and trans activity maps revealed cell type-specific active enhancers bound by differentially expressed TFs. 000
Xiaoxu Yang @xiaoxuyang.bsky.social · 08/01/2025Highlights • H3K4me1 ChIP-STARR-seq enabled the quantification of cell type-specific enhancer activities with high-resolution. • Cross-transfection of the ChIP-STARR-seq libraries into two cell lines revealed the enhancers cis and trans activity maps. 100
Xiaoxu Yang @xiaoxuyang.bsky.social · 08/01/2025High-resolution dissection of human cell type-specific enhancers in cis and trans activities (sciencedirect.com/science/arti...) a long journey form @wang__meng and Dr. Wu, glad to be part of this! 100