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Xiaotian

@xiaotian-lu.bsky.social
8 followers 26 following 1 posts
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Reposted by Xiaotian
Dean Astumian, OFS @deanast.bsky.social · 29/07/2026
New paper out detailing how kinetic asymmetry can lead to single enzyme chemotaxis and apparent non-reciprocal interactions between enzymes: doi.org/10.1002/smll...
doi.org
Molecular Active Matter, Kinetic Asymmetry, and Non‐Reciprocal Interactions
Nanoscale enzymes constitute dissipative active matter that converts scalar energy input into vectorial outputs. Through kinetic and diffusion asymmetry, they break time and space symmetry, resulting....
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Reposted by Xiaotian
Dean Astumian, OFS @deanast.bsky.social · 13/05/2026
Just out in ACS Nano, Congratulations Xiaotian! Emergent Nonlinearity in Active Molecular Chemotaxis | ACS Nano pubs.acs.org/doi/10.1021/...
pubs.acs.org
Emergent Nonlinearity in Active Molecular Chemotaxis
Understanding chemotaxis at the molecular level is challenging, as individual enzyme molecules cannot sense chemical gradients across their nanometer-sized bodies. Typical theoretical models encompass...
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Reposted by Xiaotian
Ayusman Sen @ayusmansen.bsky.social · 13/05/2026
Chemotactic velocity of enzymes emerges from a nonlinear coupling between the enzyme’s spatial distribution, its conformational state, and chemical gradients from catalysis. Great work by @xiaotian-lu.bsky.social Emergent Nonlinearity in Active Molecular Chemotaxis pubs.acs.org/doi/10.1021/...
pubs.acs.org
Emergent Nonlinearity in Active Molecular Chemotaxis
Understanding chemotaxis at the molecular level is challenging, as individual enzyme molecules cannot sense chemical gradients across their nanometer-sized bodies. Typical theoretical models encompass...
032
Reposted by Xiaotian
Ayusman Sen @ayusmansen.bsky.social · 05/05/2026
Great work by @ektashandilya.bsky.social and @xiaotian-lu.bsky.social. Shifts the paradigm from passive, receptor-based delivery to dynamic, energy-responsive targeting. Chemotaxis of ATPase-Powered Nanoparticles up Extra- and Intracellular ATP Gradients | Nano Letters pubs.acs.org/doi/10.1021/...
pubs.acs.org
Chemotaxis of ATPase-Powered Nanoparticles up Extra- and Intracellular ATP Gradients
Guiding synthetic nanomaterials toward specific cells and subcellular organelles remains a critical challenge for targeted therapeutics. Here, we report that ATPase-functionalized nanoparticles harnes...
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Reposted by Xiaotian
Ayusman Sen @ayusmansen.bsky.social · 25/03/2026
Our By-the-Numbers article on "Chemically powered active particle colonies" in Nature Chemical Engineering: rdcu.be/e91MQ
rdcu.be
Chemically powered active particle colonies
Nature Chemical Engineering - Xiaotian Lu and Ayusman Sen discuss the principles underlying the design of active particle populations with distributed functionality that collectively perform...
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