Wouter van Snippenburg @wvansnippenburg.bsky.social · 26/01/2026Still, I only use infusions of 30 minutes myself. Even less pronounced increase in paCO2 010
Wouter van Snippenburg @wvansnippenburg.bsky.social · 26/01/2026The "doesn't increase pH unless increase in ventilation is a myth": pubmed.ncbi.nlm.nih.gov/10923730/ Temporary increase in CO2 production = temporary increase in paCO2, which goes back to baseline without change in minute ventilation, maintaining an increase in pH that's there from the start. 200
Wouter van Snippenburg @wvansnippenburg.bsky.social · 08/12/2025Is it accurate though? Sodium is only a minor contributor to the mass of the drug, e.g. 1 gram of ampicillin contains 62 mg sodium = 2.7 mmol. So there's only a sodium problem if you dissolve it in high volume of NaCl 0,9%, which isn't necessary (at least not for amoxi/flucloxacillin which I use). 030
Wouter van Snippenburg @wvansnippenburg.bsky.social · 24/07/2025Probably should have added some tags? #emimcc #medsky #foamed #foamcc 010
Wouter van Snippenburg @wvansnippenburg.bsky.social · 24/07/2025I made some improvements to my Stewart acid-base calculator, I think some of you might find it useful as well: medischesnippers.nl/stewart/ Let me know if you find any bugs or errors. @pulmcrit.bsky.social @kidneyboy.bsky.socialmedischesnippers.nlAcid-base calculator using Stewart's quantitative approach 292
Wouter van Snippenburg @wvansnippenburg.bsky.social · 24/06/2025The formula can be simplified to 5 mL/kg NaCl 3% which will result in an expected increase of about 3 mM in men and about 4 mM in women. Or 0,5 mL/kg NaCl 23.4% again for an expected 3 mM increase in men and 4 mM in women. Holds quite well for starting [Na] 110-150 mM and easy to calculate. 100
Wouter van Snippenburg @wvansnippenburg.bsky.social · 12/05/2025In my experience i.v. does lower the blood pressure quite well without causing a significant drop in heart rate. So I'm surprised by this. What's your experience? Maybe the composition varies by manufacturer? 100
