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Will Herrington

@willkidney.bsky.social
164 followers 296 following 9 posts

Kidney doctor and professor of clinical trials and epidemiology of kidney disease at CTSU, University of Oxford. EMPA-KIDNEY & EASi-KIDNEY CI. Needs to be large & randomized (or a bike!)

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Will Herrington @willkidney.bsky.social · 26/11/2025
2025 @thelancet.com #CKD seminar out! Read it for latest evidence on how to manage what is projected to become a top 5 leading cause of death globally by 2050 (read it so in 25years’ time that does not happen…): www.sciencedirect.com/science/arti...
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Will Herrington @willkidney.bsky.social · 26/11/2025
Important link to a @jama.com collaborative meta-analysis should you need to know more about the effects of #SGLT2i on kidney, CV, mortality and hospitalization outcomes in patients with and without diabetes, and at low levels of albuminuria: jamanetwork.com/journals/jam...
jamanetwork.com
Net Absolute Effects of Sodium Glucose Cotransporter 2 Inhibitors
This meta-analysis assesses the relative and absolute effects for use of sodium-glucose cotransporter 2 inhibitors across efficacy and safety outcomes, including kidney disease progression, among tria...
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Reposted by Will Herrington
Oxford Population Health @oxpop.bsky.social · 25/11/2025
🎉Over 300 sites are now collaborating in the EASi-KIDNEY trial! 📉EASi-KIDNEY will investigate whether a novel treatment can help slow the progression of chronic kidney disease (CKD) ➡️ buff.ly/PXTVVeE
EASi-KIDNEY trial 300+ sites
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Will Herrington @willkidney.bsky.social · 12/10/2025
Almost all u need 2 know about the remarkable clinical effects of #SGLT2i on the kidney in a wide ranging IPD metaanalysis (covers effects by albuminuria, predicted eGFR dip and novel exploratory eGFR slope methods). Please do read it! @oxpop.bsky.social @martinlandray.bsky.social
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Will Herrington @willkidney.bsky.social · 20/08/2025
3000th #EASi-KIDNEY pt screened. The aim is to accelerate & maximize recruited b4 Xmas 🎄 💝 Final target=11000 randomized! Nephrology showing we can recruit #CKD rapidly & at scale. Thank you for everyone’s perseverance during setup. 🤩 ⁦‪⁦‪@Oxford_NDPH‬⁩ ⁦‪@DCRINews‬⁩
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Will Herrington @willkidney.bsky.social · 21/07/2025
We don’t want travel insurance companies to punish trial volunteers - the treatments we all rely upon are thanks to volunteers from the past, present and future. Worth everyone subsiding. Agreed? If so, please sign below….! petition.parliament.uk/petitions/72...
petition.parliament.uk
Petition: Ban travel insurance premium hikes & refusals for people in clinical trials
Ban travel insurance companies vastly increasing premiums, or refusal to cover people who partake in clinical trials, which may make it impossible for them to travel without resulting in substantial a...
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Reposted by Will Herrington
European Journal of Human Genetics @ejhg-journal.bsky.social · 18/06/2025
Collider bias affects genome-wide association studies (GWAS) of disease progression phenotypes. @willkidney.bsky.social ney.bsky.social This study reports a method to reduce this bias. Find out more ⬇️ www.nature.com/articles/s41...
nature.com
An application of the MR-Horse method to reduce selection bias in genome-wide association studies of disease progression - European Journal of Human Genetics
European Journal of Human Genetics - An application of the MR-Horse method to reduce selection bias in genome-wide association studies of disease progression
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Will Herrington @willkidney.bsky.social · 12/06/2025
@ukkidney.org anaemia in #CKD guidelines head-to-head with @kdigo.org draft statements at #UKKW25 debate in Bournemouth. Exact Hb threshold may be as low as 9 g/dL (or as high as 10.5!) DW vs SB.
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Reposted by Will Herrington
ISNkidneycare @theisn.org · 23/05/2025
🌍 History made! For the first time, kidney care is on the global health agenda. #WHA78 adopted a landmark resolution recognizing kidney health in the fight against #NCDs. 👏 Thanks to Guatemala and the global kidney community for making this possible! #KidneyHealthMatters
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Will Herrington @willkidney.bsky.social · 16/05/2025
In 1978, the idea that large randomized trials was born in this important Richard Peto paper….Rory Collins telling the story of CTSU @oxpop.bsky.social (following Rona Smith’s talk describing large dialysis trial in progress 47 years later!)
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Will Herrington @willkidney.bsky.social · 16/05/2025
#EASi-KIDNEY recruitment building globally! Nephrology aiming to show the world we can complete mega-trials (target 11,000 recruits). @oxpop.bsky.social Parminder Judge presenting to the UK collaboration today thanking sites for pushing through the startup processes (more at www.easikidney.org)
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Will Herrington @willkidney.bsky.social · 13/05/2025
Interesting preliminary data on SGLT2i in ADPKD on background of tolvaptan. Worthy of larger trials….
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