Hello blue sky, it's been a while. The Hancock and Rice labs are proud to announce our recent single-molecule work on microtubule dynamics by Sarada Mondal. New intermediate binding state of tubule to Mt end. GTP hydrolysis preferentially weakens lateral interactions.
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Single-molecule microtubule dynamics measurements reveal an intermediate state and clarify the role of nucleotide
Nature Communications - The authors use single-molecule imaging to define the strength and nucleotide-dependence of tubulin:microtubule interactions. They discover an intermediate state and show...
