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Wei Bian

@weibian.bsky.social
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Reposted by Wei Bian
Matthias Soller @matthiassoller.bsky.social · 20/08/2026
Thanks to @yuantian23.bsky.social our preview: A splicing twist from Ψ authors.elsevier.com/a/1neIF3vVUP... [kwnsfk27.r.eu-west-1.awstrack.me] www.cell.com/molecular-ce...
cell.com
A splicing twist from Ψ
In this issue of Molecular Cell, Meng et al. identify a reader for pseudouridine (Ψ) in mRNA. Ψ increases binding of SMD2, a member of the SM protein ring surrounding spliceosomal U1 and U2 snRNAs, an...
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Reposted by Wei Bian
Deepanshu Singh @deepanshund.bsky.social · 21/08/2026
Excited to share our latest pre-print. Here we uncover a new role of Dpp/BMP signalling in regulating neuronal wiring of Sex Peptide Response Inducing Neurons (SPRINz). Thanks to @matthiassoller.bsky.social #drosophila #sexpeptide #BMP #Dpp #neuroconnectivity www.biorxiv.org/content/10.6...
biorxiv.org
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Reposted by Wei Bian
Matthias Soller @matthiassoller.bsky.social · 11/02/2026
Excited to share our tour de force in identifying neurons in the brain as targets of a seminal peptide thanks to Karthik Nallasivan and @deepanshund.bsky.social @mcf-uom.bsky.social @fbmh-uom.bsky.social published in @elife.bsky.social elifesciences.org/articles/98283
elifesciences.org
Sex peptide targets distinct higher order processing neurons in the brain to induce the female post-mating response
Sex peptide response-inducing neurons (SPRINz) in the central brain can induce female post-mating responses through sex peptide received by mating.
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Reposted by Wei Bian
Matthias Soller @matthiassoller.bsky.social · 13/12/2025
Elegant way to test for CRISPR-Cas9 off targets thanks to @weibian.bsky.social @davidmcquarrie.bsky.social @roliarnold.bsky.social @ihaussmann.bsky.social but there seems very little. At least to say CRISPR-Cas9 is safe for flies rdcu.be/eUyma
rdcu.be
Genetic evaluation of CRISPR-Cas9 off-target effects from deleterious mutations on Drosophila male single X chromosome
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Reposted by Wei Bian
Matthias Soller @matthiassoller.bsky.social · 05/12/2024
Here is the link platinum-crispr.bham.ac.uk/predict.pl
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Reposted by Wei Bian
Matthias Soller @matthiassoller.bsky.social · 13/11/2024
Excited to share our new paper describing how ELAV/Hu RNA binding proteins achieve binding specificity now in NAR thanks to fantastic @davidmcquarrie.bsky.social academic.oup.com/nar/article/...
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Reposted by Wei Bian
David McQuarrie @davidmcquarrie.bsky.social · 21/11/2024
N-6-methyladenosine (m6A) Promotes the Nuclear Retention of mRNAs with Intact 5' Splice Site Motifs www.biorxiv.org/content/10.1...
biorxiv.org
N-6-methyladenosine (m6A) Promotes the Nuclear Retention of mRNAs with Intact 5' Splice Site Motifs
In humans, misprocessed mRNAs containing intact 5′ Splice Site (5′SS) motifs are nuclear retained and targeted for decay by ZFC3H1, a component of the Poly(A) Exosome Targeting complex, and U1-70K, a ...
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