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Watchmaker Genomics

@watchmakergenomics.bsky.social
242 followers 147 following 275 posts

Advancements in breakthrough omics and molecular biology applications are limited by enzyme and reagent quality. Let's change that. www.watchmakergenomics.com

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Watchmaker Genomics @watchmakergenomics.bsky.social · 30/06/2026
How it started: Quantify. Calculate. Dilute. Pool. Hope. How it's going: Normalize. Pool. Sequence. Replacing manual quantify-&-dilute workflows with rapid normalization, EquiPlex™ helps reduce opportunities for error while making it easier to achieve balanced sequencing pools
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Watchmaker Genomics @watchmakergenomics.bsky.social · 24/06/2026
Choosing a library amplification mix used to mean compromise. Until now. Equinox Prime delivers high-fidelity amplification with excellent yield, GC coverage uniformity, PCR efficiency, & reduced polymerase slippage. Learn more in the comments. #NoCompromise #NGS #Genomics
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Watchmaker Genomics @watchmakergenomics.bsky.social · 23/06/2026
Let’s #ThrowbackThursday to #AGBT2026! Our collaboration with @atlasxomics.bsky.social , NYU Langone Health, & Ultima Genomics combined spatial ATAC-TAPS+ to map chromatin accessibility + DNA methylation in one tissue section. Full poster in the comments. 👇
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Watchmaker Genomics @watchmakergenomics.bsky.social · 17/06/2026
That’s a wrap on #ESHG2026! Great week in Gothenburg discussing TAPS+, EquiPlex, & Equinox Prime with the human genetics community. Thanks to those who joined our workshop, visited our posters, & stopped by Booth 256. Link in comments for workshop & poster copies! #Genomics #NGS
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Watchmaker Genomics @watchmakergenomics.bsky.social · 16/06/2026
Don't let your library amplification mix have you slippin’. Polymerase slippage creates false indels in homopolymers & repetitive regions - especially problematic for MSI profiling. Equinox Prime reduces indel errors so repeat lengths better reflect biological reality. #SkipTheSlip #NGS #Genomics
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Watchmaker Genomics @watchmakergenomics.bsky.social · 12/06/2026
Heading to #ESHG2026? Join us in Gothenburg! View our posters on methylation sequencing & PCR-free WGS Sunday, then attend our workshop Monday: "From Multiomics to Multiplexing." Visit Booth 256 for details, posters & more: watchmakergenomics.com/events/eshg2026
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Watchmaker Genomics @watchmakergenomics.bsky.social · 11/06/2026
You've heard the normalization promises before. We built EquiPlex differently. No template destruction. No library jackpotting. No dilution calculations. No variable-volume pipetting. Just fast, simple normalization that fits existing #NGS workflows. Data in comments. #Genomics
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Watchmaker Genomics @watchmakergenomics.bsky.social · 10/06/2026
Finally! No more trade-offs in library amplification. 🎉 Equinox Prime is here. ✔ Up to 55% lower polymerase error rates ✔ Reduced slippage for improved indel calling ✔ Uniform GC coverage ✔ Fewer PCR cycles, higher yield Learn more: link in comments. #NGS #Genomics
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Watchmaker Genomics @watchmakergenomics.bsky.social · 09/06/2026
As sequencing workflows scale, bottlenecks in normalization, pooling, & amplification can impact efficiency & data quality. At #ESHG2026, we're unveiling EquiPlex & Equinox Prime. Visit Booth 256 & join our June 15 workshop to learn more. Full announcement: link in comments.
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Watchmaker Genomics @watchmakergenomics.bsky.social · 04/06/2026
👋 Watchmaker is at #SEASR & ready to chat about how our #NGS solutions are helping labs streamline workflows, improve accuracy, & get more out of every sample. Stop by & chat about your sequencing challenges, or to see how Watchmaker can help you get more out of every sample. 🧬
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Watchmaker Genomics @watchmakergenomics.bsky.social · 03/06/2026
Join Watchmaker at #ESHG2026 for a 90-minute workshop with Dr. Laura Glaser (MGZ) & Dr. Pieter Mestdagh (CellCarta) on improving sequencing accuracy & scalability. We’ll also unveil Equinox Prime & EquiPlex Normalization. Visit us at Booth 256! www.watchmakergenomics.com/events/eshg2...
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Watchmaker Genomics @watchmakergenomics.bsky.social · 02/06/2026
For the 4th year in a row, our Watchmakers teamed up with #HabitatForHumanity to help build a home for a family in need. 🏡🔨 From painting & nailing to sealing gaps, the team put their skills to work, & learned that “measure twice, cut once” is easier said than done. 😅
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Watchmaker Genomics @watchmakergenomics.bsky.social · 28/05/2026
Data isn’t the only thing our teams have been generating lately. 😅 Across Boulder & Cape Town, Watchmakers came together to support survivors, vulnerable children, & local communities through donation drives, food support, & Slipper Day giving. #WatchmakerGivesBack
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Watchmaker Genomics @watchmakergenomics.bsky.social · 27/05/2026
FFPE & cfDNA samples keep sequencing teams humble 😅 Low input. Damage. Artifacts. Coverage headaches. But difficult samples shouldn’t mean compromised data. Watchmaker’s high-efficiency #NGS library prep solutions help maximize usable insights from challenging samples. 🔑🧬
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Watchmaker Genomics @watchmakergenomics.bsky.social · 21/05/2026
Why are developers switching from LAMP to RPA for point-of-care testing? RPA offers simpler 2-primer design, lower temps (~40°C), results in <10 min, strong inhibitor tolerance, & easier multiplexing - even from crude samples. More in the comments. #MolecularDiagnostics #RPA
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Watchmaker Genomics @watchmakergenomics.bsky.social · 20/05/2026
We’re headed to Santa Fe for the 20th Annual #SFAFMeeting, a uniquely technical genomics meeting built around real discussion between academia, industry, & government. Excited to talk sequencing performance, scaling workflows, & multiomic data. If you’re there, Sara & Frankie would love to connect!
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Watchmaker Genomics @watchmakergenomics.bsky.social · 14/05/2026
What’s it like to work at Watchmaker? Fast-moving, collaborative, and focused on solving hard problems in genomics. We’re hiring curious, driven people who want to build meaningful things alongside a smart, supportive team. Open roles in the comments. #Hiring
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Watchmaker Genomics @watchmakergenomics.bsky.social · 13/05/2026
Cancer research is built on difficult samples: aged FFPE tissue, ultra-low input liquid biopsies, & hard-to-recover signals. During Cancer Research Month, we’re recognizing the researchers turning challenging samples into meaningful data & progress. #CancerResearchMonth
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Watchmaker Genomics @watchmakergenomics.bsky.social · 12/05/2026
Missed #ESCMIDGlobal2026? Catch Curtis on-demand as he shares how new RT-qPCR/qPCR chemistry enables rapid, extraction-free pathogen detection from crude samples with strong inhibitor tolerance, fast cycling, & reliable performance. 🎥 Link in comments
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Watchmaker Genomics @watchmakergenomics.bsky.social · 07/05/2026
At Watchmaker, great chemistry is just the start - scaling it is where it counts. Our Process Development team ensures enzymes, buffers, & kits perform consistently from bench to production, delivering reliable supply & fewer surprises. #ScaleUpSquad #NGS #Genomics
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Watchmaker Genomics @watchmakergenomics.bsky.social · 06/05/2026
🎸 We don’t need no degradation. Hey! Bisulfite! Leave those bases alone. TAPS+ delivers the full spectrum from one library: SNVs, indels, CNVs, and methylation. No harsh chemistry. No DNA damage. Just complete data. 🌈 🔬 See more: Link in comments #Epigenomics #TAPS #Genomics
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Watchmaker Genomics @watchmakergenomics.bsky.social · 30/04/2026
🌎 This Earth Day, WOUCHEE took “spring cleaning” outdoors. The Boulder team spent the afternoon cleaning up a bike path & along with the standard litter haul, we also managed to pull a rug out of the river, which was not on anyone’s bingo card. 😅 #EarthDay #CleanUpCrew
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Watchmaker Genomics @watchmakergenomics.bsky.social · 21/04/2026
RPA Fast Facts, Pt 2: How does #RPA actually work? In this video, take a closer look at the underlying chemistry behind recombinase polymerase amplification, including how exponential amplification occurs without thermal cycling. For more details, click the link in the comments
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Watchmaker Genomics @watchmakergenomics.bsky.social · 16/04/2026
We’re off to San Diego for #AACR2026! Excited to connect with oncology community & share NGS innovation in tumor biology & biomarker discovery. Featuring TAPS+, Equinox Prime, & EquiPlex. Check out our posters on Mon - #1951 at 9AM & #3213 at 2PM #CancerResearch #Epigenetics
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Watchmaker Genomics @watchmakergenomics.bsky.social · 15/04/2026
Introducing our RPA Fast Facts video series. We’re breaking down why recombinase polymerase amplification (RPA) is gaining traction for point-of-care & rapid testing. First: why developers are moving from LAMP to RPA. More to come - link in comments. #MolecularDiagnostics #RPA
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Watchmaker Genomics @watchmakergenomics.bsky.social · 14/04/2026
Skip the cleanup. Keep the signal. Introducing Stellar RT-qPCR & qPCR Kits - built for inhibitor tolerance, enabling direct amplification from crude samples without sacrificing performance. Faster results, high sensitivity, & less prep. #MolecularDiagnostics #InfectiousDisease
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Watchmaker Genomics @watchmakergenomics.bsky.social · 09/04/2026
High-performing chemistries don’t happen by accident. Our R&D Applications Development Group bridges innovation, customer needs, & commercialization, advancing workflows from concept to launch. Turning great enzyme design into solutions that work. #AppsIsAwesome #NGS #Genomics
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Watchmaker Genomics @watchmakergenomics.bsky.social · 08/04/2026
We’re headed to #ESCMIDGlobal2026 in Munich & excited to connect with the clinical microbiology community. Introducing a new qPCR/RT-qPCR chemistry for fast, extraction-free amplification from tough samples. 📅 Sun, April 19 | 10:30–10:50 AM 📍 Booth G37 #MolecularDiagnostics
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Watchmaker Genomics @watchmakergenomics.bsky.social · 31/03/2026
#ABRF2026, you delivered. Great conversations, excellent sessions, & top-tier karaoke 🎤 Always a highlight to spend time with such an engaged & collaborative community. Miss our session, or didn't get to stop by the booth? Check out our ABRF page in the comments. Until next time!
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Watchmaker Genomics @watchmakergenomics.bsky.social · 30/03/2026
ABRF friends, see you tomorrow! ☀️🥂 Join our breakfast workshop: From Multiomics to Multiplexing 7:45–8:45 AM | Room 411–412 TAPS+, EquiPlex, and practical ways to scale genomics cores without sacrificing efficiency. Mimosas are included. See us in Booth 304 after!
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Watchmaker Genomics @watchmakergenomics.bsky.social · 25/03/2026
Off to #ABRF2026 in Pittsburgh! 🚀 Join us for mimosas & breakfast at our Tech Showcase on March 31, 7:45–8:45 AM, Room 411–412. We’ll spotlight TAPS+, EquiPlex & practical strategies for NGS cores. Chat with us in Booth 304! #GenomicsCore #Epigenetics
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Watchmaker Genomics @watchmakergenomics.bsky.social · 24/03/2026
Automation at scale - no compromise to #RNAseq performance. At SLAS with Agilent, we presented a poster on automating the Watchmaker mRNA Library Prep Kit on Bravo NGS. Result: manual-equivalent results, high reproducibility, no cross-contamination, 96 samples in ~7 hrs.
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Watchmaker Genomics @watchmakergenomics.bsky.social · 19/03/2026
Together with Elevate Bio, we automated the Watchmaker mRNA Library Prep Kit on the Biomek i7 - delivering high-quality RNA-seq libraries across 10–200 ng input with consistent performance. Scalable, high-throughput automation without compromise. #RNAseq #LabAutomation
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Watchmaker Genomics @watchmakergenomics.bsky.social · 18/03/2026
Scaling NGS workflows shouldn’t mean more complexity. At Watchmaker, we help labs break bottlenecks with automation-ready workflows & high-throughput formats - so your science scales without slowing down. 🤖 Vetted automation scripts ⚡ High-throughput ready 📈 Built for scale #NGS #Genomics
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Watchmaker Genomics @watchmakergenomics.bsky.social · 04/03/2026
We’re at #PMWC26 connecting with leaders in precision medicine & diagnostics. Exciting interest in TAPS+ direct methylation library prep for integrated genetic + epigenetic analysis - especially in liquid biopsies. Visit booth C935 or catch Craig Marshall tomorrow at 9:45 AM! #Epigenetics
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Watchmaker Genomics @watchmakergenomics.bsky.social · 24/02/2026
TODAY 1:30 PM: catch our poster on rapid, PCR-free WGS w/ streamlined normalization for faster turnaround + strong performance. Don’t miss our talk Wed 3:20 PM. Swing by Manatee for free espresso 10–12 ☕️ #AGBTGM26 #WGS #Genomics #AGBT
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Watchmaker Genomics @watchmakergenomics.bsky.social · 23/02/2026
@voltalabs.bsky.social just launched the Callisto™ Complete Kit for DNA EF Library Prep—powered by Watchmaker chemistry. Fully automated, PCR-free WGS with push-button simplicity for labs running at practical mid-throughput scale. #NGS #Genomics
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Watchmaker Genomics @watchmakergenomics.bsky.social · 20/02/2026
🥼❄️ While the world watched the Winter Olympics, our Cape Town + Boulder teams went for gold in the first Watchmaker Lab Olympics (no real lab benches harmed). Lab-letes battled it out in Pipette Long Range, Label Trials & the legendary Wet Glove Challenge. 🏅
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Watchmaker Genomics @watchmakergenomics.bsky.social · 19/02/2026
Headed to #AGBTGM26 with new data + big ideas. We’re sharing how we’re driving a step change in end-to-end WGS—less complexity, lower DNA input, better efficiency. Catch our talk Wed 3:20–3:35 + poster Tue 1:30–3:30 (#461). Let’s rethink genome workflows.
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Watchmaker Genomics @watchmakergenomics.bsky.social · 18/02/2026
Watchmaker Genomics licensed CRISPR-Cas9 IP from Caribou Biosciences to rethink NGS library normalization, no genome editing, just smarter workflows. This will power our upcoming PCR-free WGS solution. Learn more at #AGBTGM2026. #NGS #WGS
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Watchmaker Genomics @watchmakergenomics.bsky.social · 17/02/2026
🐎 Year of the Horse = strength, momentum, and determination, exactly what we see from our commercial team in China every day. Thanks for the drive and partnership that keep our science moving. Wishing everyone a joyful, prosperous Lunar New Year! 新年快乐! 🧧
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Watchmaker Genomics @watchmakergenomics.bsky.social · 11/02/2026
We’re in our STEMinist era 🧬On International Day of Women & Girls in Science, we’re celebrating the women who ask hard questions, challenge assumptions, & turn ideas into results. They don’t just contribute to science, they shape it. STEMinist swag coming soon (link in comments)
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Watchmaker Genomics @watchmakergenomics.bsky.social · 09/02/2026
🚀 SLAS 2026 is underway! Our Automation team + collaborators are presenting 4 posters over 3 days showcasing scalable, high-performance automated genomics workflows. Catch us 12–1 PM in Exhibit Halls AB, and don’t miss the SPT Labtech talk on Tuesday!
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Watchmaker Genomics @watchmakergenomics.bsky.social · 05/02/2026
We’re excited to collaborate with Visby Medical on next-generation, at-home PCR testing for respiratory pathogens. By pairing instrument-free PCR with Watchmaker’s inhibitor-tolerant enzymes, we’re enabling fast, reliable results from real-world samples. #MolecularDiagnostics #InfectiousDisease
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Watchmaker Genomics @watchmakergenomics.bsky.social · 04/02/2026
Our #automation team is heading to #SLAS2026! 🧬 We’ll share posters on automated sequencing & DNA methylation workflows, plus showcase how automation + smart chemistry boost data quality & scalability. Stop by to chat with Eleanor, Cole, Jimmy & Callum! #WorkflowAutomation
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Watchmaker Genomics @watchmakergenomics.bsky.social · 03/02/2026
If your feed has been whispering “new job energy”… this might be your sign ✨ We’re hiring across teams and regions, from NGS sales and FAS roles to product leadership. If genomics is your thing, check out our open roles 👀 www.watchmakergenomics.com/company/care...
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Watchmaker Genomics @watchmakergenomics.bsky.social · 28/01/2026
🥳 End-of-year holiday party - fashionably late and very competitive. With our remote teams and Boulder office together, we took a break from our commercial meeting for games, scavenger hunts, and plenty of friendly rivalry at Dave & Buster’s. 🕹️🏆
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Watchmaker Genomics @watchmakergenomics.bsky.social · 28/01/2026
🎉 Day 1 at #FOGUK! Great conversations at booth 85 with teams tackling cancer & clinical genomics challenges. We’re presenting 2 posters on tough samples & high-value data. Working with FFPE or cfDNA? Come chat. 📍Booth 85 watchmakergenomics.com/events/fog2026
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Watchmaker Genomics @watchmakergenomics.bsky.social · 27/01/2026
✨ New year, same commitment to giving back. Our Cape Town team hosted a stationery drive for underprivileged kids in Fraserburg, Karoo, while our Boulder team donated blood to Children's Hospital Colorado. Different efforts, one goal: making a positive impact. 🌍💙
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Watchmaker Genomics @watchmakergenomics.bsky.social · 26/01/2026
We’re proud to share that Watchmaker has renewed our ISO 13485 certification. This milestone reflects the strength of our quality systems and our commitment to reliable, high-performance solutions built to meet rigorous regulatory standards. Link in comments.
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