Researchers at the University of Wisconsin–Madison have uncovered new evidence in a decades-old genetic mystery, discovering how multiple genetic variations in a long-mysterious region of the human ge...

Coronary dominance is a clinically important developmental phenotype that dictates whether the left or right coronary arteries perfuse the back of the heart. Genome-wide association studies and downst...

BACKGROUND: Genome-wide association studies have identified common genetic variants at ≈300 human genomic loci linked to coronary artery disease susceptibility. Among these genomic regions, the most i...

A foundation model learns transcriptional regulatory syntax from chromatin accessibility and sequence data across a range of cell types to predict gene expression and transcription factor interactions...

A vascular cell atlas integrating single-cell data of 19 organs and tissues from 62 donors identifies angiotypic and organotypic characteristics of endothelial and mural cells.