iiinova — where your digital self keeps evolving

Perimenopause and Work: Findings from the AMY Study • Research Presentation at the International Menopause Society Congress 2026

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Perimenopause and Work: Findings from the AMY Study

Research Presentation at the International Menopause Society Congress 2026

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The Vajenda @vajenda.skystack.xyz · 01/10/2026

Effect of Transdermal Testosterone on Muscle Mass in Post Menopausal Women • Update from the IMS 2026 Congress

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Effect of Transdermal Testosterone on Muscle Mass in Post Menopausal Women

Update from the IMS 2026 Congress

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The Vajenda @vajenda.skystack.xyz · 23/09/2026

Inside the FDA’s Testosterone Workshop • Day 2: Safety Data, Gel Data, and What the FDA is Looking for in Submissions

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Inside the FDA’s Testosterone Workshop

Day 2: Safety Data, Gel Data, and What the FDA is Looking for in Submissions

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The Vajenda @vajenda.skystack.xyz · 21/09/2026

The FDA’s Testosterone Hearing: Use in Menopausal Women • Part 1: What We Actually Know About Testosterone for Women and the Current Products

vajenda.substack.com

The FDA’s Testosterone Hearing: Use in Menopausal Women

Part 1: What We Actually Know About Testosterone for Women and the Current Products

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The Vajenda @vajenda.skystack.xyz · 15/09/2026

Testosterone to Increase Exercise Capacity in Women with Early Heart Failure: A Randomised Controlled Trial • Update from the Australasian Menopause Society Annual Congress

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Testosterone to Increase Exercise Capacity in Women with Early Heart Failure: A Randomised Controlled Trial

Update from the Australasian Menopause Society Annual Congress

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The Vajenda @vajenda.skystack.xyz · 13/09/2026

Bone Health Without the Hype • 10 lessons from the Australasian Menopause Society meeting: DXA, estrogen doses, and more

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Bone Health Without the Hype

10 lessons from the Australasian Menopause Society meeting: DXA, estrogen doses, and more

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The Vajenda @vajenda.skystack.xyz · 28/08/2026

Before You Share That New "HRT Prevents Dementia" Study, Read the Fine Print • It found no benefit for most women, and it’s observational

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Before You Share That New "HRT Prevents Dementia" Study, Read the Fine Print

It found no benefit for most women, and it’s observational

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The Vajenda @vajenda.skystack.xyz · 20/08/2026

The Estrogen-Alzheimer’s Hype Machine • Why one observational study can’t turn a hypothesis into a treatment

vajenda.substack.com

The Estrogen-Alzheimer’s Hype Machine

Why one observational study can’t turn a hypothesis into a treatment

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The Vajenda @vajenda.skystack.xyz · 30/07/2026

MIDI and the Making of Female Testosterone Deficiency • Historical medical neglect is not an excuse to lower the evidence standard

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MIDI and the Making of Female Testosterone Deficiency

Historical medical neglect is not an excuse to lower the evidence standard

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The Vajenda @vajenda.skystack.xyz · 23/07/2026

Why Did a Reasonable Menopause Article Cause So Much Outrage? • I fact-checked the Guardian piece, and the backlash reveals a larger problem in menopause discourse

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Why Did a Reasonable Menopause Article Cause So Much Outrage?

I fact-checked the Guardian piece, and the backlash reveals a larger problem in menopause discourse

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The Vajenda @vajenda.skystack.xyz · 19/07/2026

What Happens When Women ACTUALLY Get State-of-the-Art Medical Care in Menopause? • A new study is recruiting to answer that question

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What Happens When Women ACTUALLY Get State-of-the-Art Medical Care in Menopause?

A new study is recruiting to answer that question

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The Vajenda @vajenda.skystack.xyz · 04/07/2026

Bleeding on Menopause Hormone Therapy and a Proliferative Endometrium • What this biopsy finding means, how it changes endometrial cancer risk, and why it should never be dismissed

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Bleeding on Menopause Hormone Therapy and a Proliferative Endometrium

What this biopsy finding means, how it changes endometrial cancer risk, and why it should never be dismissed

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The Vajenda @vajenda.skystack.xyz · 25/06/2026

10 Reasons Natural Menopause Is Not a Castration Event • The analogy may be attention-grabbing, but the physiology tells a different story

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10 Reasons Natural Menopause Is Not a Castration Event

The analogy may be attention-grabbing, but the physiology tells a different story

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The Vajenda @vajenda.skystack.xyz · 21/06/2026

Evidence, Economics, and Menopause • Estradiol levels with Prof. Sue Davis, new data showing how free contraception saves money, and tomorrow’s Substack Live with world-renowned reproductive endocrinologist Dr. Nanette Santoro.

vajenda.substack.com

Evidence, Economics, and Menopause

Estradiol levels with Prof. Sue Davis, new data showing how free contraception saves money, and tomorrow’s Substack Live with world-renowned reproductive endocrinologist Dr. Nanette Santoro.

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The Vajenda @vajenda.skystack.xyz · 18/06/2026

Testosterone After Hip Fracture: What This Trial Does, and Doesn’t, Show • A small number of secondary and post hoc findings are being misread as clinical proof, with insights from Prof Sue Davis

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Testosterone After Hip Fracture: What This Trial Does, and Doesn’t, Show

A small number of secondary and post hoc findings are being misread as clinical proof, with insights from Prof Sue Davis

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The Vajenda @vajenda.skystack.xyz · 08/06/2026

A New Study for Heavy Menstrual Bleeding Needs Your Help • Researchers are testing a wearable nerve stimulation device that may reduce menstrual bleeding. Here's what the science shows so far, and why this trial deserves attention.

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A New Study for Heavy Menstrual Bleeding Needs Your Help

Researchers are testing a wearable nerve stimulation device that may reduce menstrual bleeding. Here's what the science shows so far, and why this trial deserves attention.

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The Vajenda @vajenda.skystack.xyz · 04/06/2026

Melinda French Gates Invests Additional $215M in Women's Health • Her total commitments to women’s health now top $600 million in last two years

vajenda.substack.com

Melinda French Gates Invests Additional $215M in Women's Health

Her total commitments to women’s health now top $600 million in last two years

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The Vajenda @vajenda.skystack.xyz · 22/05/2026

Addressing the “Women Have More Testosterone Than Estrogen” Claim • Separating the science from the social media claims

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Addressing the “Women Have More Testosterone Than Estrogen” Claim

Separating the science from the social media claims

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The Vajenda @vajenda.skystack.xyz · 17/05/2026

Congrats Ladies: Midi’s Cure for Structural Oppression Is Apparently a Supplement • Inside Midi Health's “Daily Cortisol Support” and the science-ish marketing of women’s stress.

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Congrats Ladies: Midi’s Cure for Structural Oppression Is Apparently a Supplement

Inside Midi Health's “Daily Cortisol Support” and the science-ish marketing of women’s stress.

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The Vajenda @vajenda.skystack.xyz · 27/04/2026

CRP: What it Can, and Can't, Tell You • Why this inflammation marker can be useful for risk assessment, misleading for tracking, and irrelevant for menopause decisions

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CRP: What it Can, and Can't, Tell You

Why this inflammation marker can be useful for risk assessment, misleading for tracking, and irrelevant for menopause decisions

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The Vajenda @vajenda.skystack.xyz · 20/04/2026

MHT and Mortality: Reassuring Data from a New Study • A major Danish study finds no excess mortality, even with long-term use, and signals real benefits after surgical menopause

vajenda.substack.com

MHT and Mortality: Reassuring Data from a New Study

A major Danish study finds no excess mortality, even with long-term use, and signals real benefits after surgical menopause

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The Vajenda @vajenda.skystack.xyz · 16/04/2026

Estrogen is Estrogen As Far As Your Uterus is Concerned • Transdermal “bioidentical” estradiol activates the same endometrial cancer pathways as any other estrogen.

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Estrogen is Estrogen As Far As Your Uterus is Concerned

Transdermal “bioidentical” estradiol activates the same endometrial cancer pathways as any other estrogen.

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The Vajenda @vajenda.skystack.xyz · 04/04/2026

Hot Flashes on the Pill in Perimenopause? It's Possible. • Estrogen metabolism, hormone levels, and why symptoms, not lab numbers, should guide care.

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Hot Flashes on the Pill in Perimenopause? It's Possible.

Estrogen metabolism, hormone levels, and why symptoms, not lab numbers, should guide care.

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The Vajenda @vajenda.skystack.xyz · 28/03/2026

Does the Birth Control Pill Permanently Change Your Hormones? • A scary claim keeps spreading online, but the best studies don’t support it.

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Does the Birth Control Pill Permanently Change Your Hormones?

A scary claim keeps spreading online, but the best studies don’t support it.

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The Vajenda @vajenda.skystack.xyz · 23/03/2026

When Bad Science Becomes Anti-Birth Control Pill Propaganda • The claim that the pill “shrinks the clitoris” falls apart when you actually read the study

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When Bad Science Becomes Anti-Birth Control Pill Propaganda

The claim that the pill “shrinks the clitoris” falls apart when you actually read the study

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The Vajenda @vajenda.skystack.xyz · 14/03/2026

The Myth of “Brain-Safe” Vaginal Progesterone • A viral claim says oral progesterone harms the brain and vaginal progesterone is safer. What does the science say?