iiinova — where your digital self keeps evolving

Testosterone to Increase Exercise Capacity in Women with Early Heart Failure: A Randomised Controlled Trial • Update from the Australasian Menopause Society Annual Congress

vajenda.substack.com

Testosterone to Increase Exercise Capacity in Women with Early Heart Failure: A Randomised Controlled Trial

Update from the Australasian Menopause Society Annual Congress

000

The Vajenda @vajenda.skystack.xyz · 13/09/2026

Bone Health Without the Hype • 10 lessons from the Australasian Menopause Society meeting: DXA, estrogen doses, and more

vajenda.substack.com

Bone Health Without the Hype

10 lessons from the Australasian Menopause Society meeting: DXA, estrogen doses, and more

000

The Vajenda @vajenda.skystack.xyz · 28/08/2026

Before You Share That New "HRT Prevents Dementia" Study, Read the Fine Print • It found no benefit for most women, and it’s observational

vajenda.substack.com

Before You Share That New "HRT Prevents Dementia" Study, Read the Fine Print

It found no benefit for most women, and it’s observational

000

The Vajenda @vajenda.skystack.xyz · 20/08/2026

The Estrogen-Alzheimer’s Hype Machine • Why one observational study can’t turn a hypothesis into a treatment

vajenda.substack.com

The Estrogen-Alzheimer’s Hype Machine

Why one observational study can’t turn a hypothesis into a treatment

000

The Vajenda @vajenda.skystack.xyz · 30/07/2026

MIDI and the Making of Female Testosterone Deficiency • Historical medical neglect is not an excuse to lower the evidence standard

vajenda.substack.com

MIDI and the Making of Female Testosterone Deficiency

Historical medical neglect is not an excuse to lower the evidence standard

000

The Vajenda @vajenda.skystack.xyz · 23/07/2026

Why Did a Reasonable Menopause Article Cause So Much Outrage? • I fact-checked the Guardian piece, and the backlash reveals a larger problem in menopause discourse

vajenda.substack.com

Why Did a Reasonable Menopause Article Cause So Much Outrage?

I fact-checked the Guardian piece, and the backlash reveals a larger problem in menopause discourse

000

The Vajenda @vajenda.skystack.xyz · 19/07/2026

What Happens When Women ACTUALLY Get State-of-the-Art Medical Care in Menopause? • A new study is recruiting to answer that question

vajenda.substack.com

What Happens When Women ACTUALLY Get State-of-the-Art Medical Care in Menopause?

A new study is recruiting to answer that question

000

The Vajenda @vajenda.skystack.xyz · 04/07/2026

Bleeding on Menopause Hormone Therapy and a Proliferative Endometrium • What this biopsy finding means, how it changes endometrial cancer risk, and why it should never be dismissed

vajenda.substack.com

Bleeding on Menopause Hormone Therapy and a Proliferative Endometrium

What this biopsy finding means, how it changes endometrial cancer risk, and why it should never be dismissed

000

The Vajenda @vajenda.skystack.xyz · 25/06/2026

10 Reasons Natural Menopause Is Not a Castration Event • The analogy may be attention-grabbing, but the physiology tells a different story

vajenda.substack.com

10 Reasons Natural Menopause Is Not a Castration Event

The analogy may be attention-grabbing, but the physiology tells a different story

000

The Vajenda @vajenda.skystack.xyz · 21/06/2026

Evidence, Economics, and Menopause • Estradiol levels with Prof. Sue Davis, new data showing how free contraception saves money, and tomorrow’s Substack Live with world-renowned reproductive endocrinologist Dr. Nanette Santoro.

vajenda.substack.com

Evidence, Economics, and Menopause

Estradiol levels with Prof. Sue Davis, new data showing how free contraception saves money, and tomorrow’s Substack Live with world-renowned reproductive endocrinologist Dr. Nanette Santoro.

010

The Vajenda @vajenda.skystack.xyz · 18/06/2026

Testosterone After Hip Fracture: What This Trial Does, and Doesn’t, Show • A small number of secondary and post hoc findings are being misread as clinical proof, with insights from Prof Sue Davis

vajenda.substack.com

Testosterone After Hip Fracture: What This Trial Does, and Doesn’t, Show

A small number of secondary and post hoc findings are being misread as clinical proof, with insights from Prof Sue Davis

000

The Vajenda @vajenda.skystack.xyz · 08/06/2026

A New Study for Heavy Menstrual Bleeding Needs Your Help • Researchers are testing a wearable nerve stimulation device that may reduce menstrual bleeding. Here's what the science shows so far, and why this trial deserves attention.

vajenda.substack.com

A New Study for Heavy Menstrual Bleeding Needs Your Help

Researchers are testing a wearable nerve stimulation device that may reduce menstrual bleeding. Here's what the science shows so far, and why this trial deserves attention.

000

The Vajenda @vajenda.skystack.xyz · 04/06/2026

Melinda French Gates Invests Additional $215M in Women's Health • Her total commitments to women’s health now top $600 million in last two years

vajenda.substack.com

Melinda French Gates Invests Additional $215M in Women's Health

Her total commitments to women’s health now top $600 million in last two years

000

The Vajenda @vajenda.skystack.xyz · 22/05/2026

Addressing the “Women Have More Testosterone Than Estrogen” Claim • Separating the science from the social media claims

vajenda.substack.com

Addressing the “Women Have More Testosterone Than Estrogen” Claim

Separating the science from the social media claims

000

The Vajenda @vajenda.skystack.xyz · 17/05/2026

Congrats Ladies: Midi’s Cure for Structural Oppression Is Apparently a Supplement • Inside Midi Health's “Daily Cortisol Support” and the science-ish marketing of women’s stress.

vajenda.substack.com

Congrats Ladies: Midi’s Cure for Structural Oppression Is Apparently a Supplement

Inside Midi Health's “Daily Cortisol Support” and the science-ish marketing of women’s stress.

000

The Vajenda @vajenda.skystack.xyz · 27/04/2026

CRP: What it Can, and Can't, Tell You • Why this inflammation marker can be useful for risk assessment, misleading for tracking, and irrelevant for menopause decisions

vajenda.substack.com

CRP: What it Can, and Can't, Tell You

Why this inflammation marker can be useful for risk assessment, misleading for tracking, and irrelevant for menopause decisions

000

The Vajenda @vajenda.skystack.xyz · 20/04/2026

MHT and Mortality: Reassuring Data from a New Study • A major Danish study finds no excess mortality, even with long-term use, and signals real benefits after surgical menopause

vajenda.substack.com

MHT and Mortality: Reassuring Data from a New Study

A major Danish study finds no excess mortality, even with long-term use, and signals real benefits after surgical menopause

000

The Vajenda @vajenda.skystack.xyz · 16/04/2026

Estrogen is Estrogen As Far As Your Uterus is Concerned • Transdermal “bioidentical” estradiol activates the same endometrial cancer pathways as any other estrogen.

vajenda.substack.com

Estrogen is Estrogen As Far As Your Uterus is Concerned

Transdermal “bioidentical” estradiol activates the same endometrial cancer pathways as any other estrogen.

000

The Vajenda @vajenda.skystack.xyz · 04/04/2026

Hot Flashes on the Pill in Perimenopause? It's Possible. • Estrogen metabolism, hormone levels, and why symptoms, not lab numbers, should guide care.

vajenda.substack.com

Hot Flashes on the Pill in Perimenopause? It's Possible.

Estrogen metabolism, hormone levels, and why symptoms, not lab numbers, should guide care.

000

The Vajenda @vajenda.skystack.xyz · 28/03/2026

Does the Birth Control Pill Permanently Change Your Hormones? • A scary claim keeps spreading online, but the best studies don’t support it.

vajenda.substack.com

Does the Birth Control Pill Permanently Change Your Hormones?

A scary claim keeps spreading online, but the best studies don’t support it.

000

The Vajenda @vajenda.skystack.xyz · 23/03/2026

When Bad Science Becomes Anti-Birth Control Pill Propaganda • The claim that the pill “shrinks the clitoris” falls apart when you actually read the study

vajenda.substack.com

When Bad Science Becomes Anti-Birth Control Pill Propaganda

The claim that the pill “shrinks the clitoris” falls apart when you actually read the study

010

The Vajenda @vajenda.skystack.xyz · 14/03/2026

The Myth of “Brain-Safe” Vaginal Progesterone • A viral claim says oral progesterone harms the brain and vaginal progesterone is safer. What does the science say?