Sign in

UCSF Peng Lab

@ucsfpenglab.bsky.social
24 followers 53 following 2 posts

Laboratory exploring the fibroblast's role in everything

PostsRepliesMedia
UCSF Peng Lab @ucsfpenglab.bsky.social · 27/03/2026
NF-κB-activated fibroblasts orchestrate inflammaging and emergence of pro-inflammatory granzyme K+ T cells: Immunity www.cell.com/immunity/ful... Excited to present Nancy's postoctoral work @ucsfaging.bsky.social @immunox.bsky.social defining the role of aging fibroblasts in driving inflammaging.
cell.com
NF-κB-activated fibroblasts orchestrate inflammaging and emergence of pro-inflammatory granzyme K+ T cells
Aging is accompanied by significant changes to the immune system. Allen et al. demonstrate that age-related NF-κB activation in fibroblasts remodels the lung resident immune system and promotes the em...
010
UCSF Peng Lab @ucsfpenglab.bsky.social · 03/11/2025
Sharing JinYoung's latest work @ucsfaging.bsky.social @ucsfstemcell.bsky.social in collaboration with @lindsaylafave.bsky.social on how senescent fibroblasts program tumor plasticity and metabolism. JY is starting her own lab at Inha University. www.sciencedirect.com/science/arti...
sciencedirect.com
Senolytic-sensitive p16Ink4a+ fibroblasts in the tumor stroma rewire lung cancer metabolism and plasticity
Senescence has been demonstrated to either inhibit or promote tumorigenesis. Resolving this paradox requires spatial mapping and functional characteri…
051