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Yonatan Tzur

@tzurlab.bsky.social
581 followers 112 following 24 posts

Yonatan Tzur's laboratory at the Genetics dep. of the Hebrew University. focusing on meiosis, germline and genome engineering

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Reposted by Yonatan Tzur
Javier Apfeld @javierapfeld.bsky.social · 01/07/2026
Do you want to support the next generation of C. elegans researchers? We are looking for mentors with C. elegans experience, including postdocs, faculty, and scientists outside academia, to share their knowledge and career advice with early career researchers. Sign up to become a mentor!
forms.gle
Mentor sign-up for the C. elegans Community Mentor Match program - 2026
Thanks for volunteering to be a Mentor! The 2026 cycle of the C. elegans Community Mentor Match is open to graduate students, postdocs and faculty at any career stage. This survey collects information...
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Yonatan Tzur @tzurlab.bsky.social · 07/07/2026
It was a delight to collaborate on this project. Good luck in your new position. I am certain we will hear about the amazing things that you will be doing there!
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Ethan (Chee Kiang) Ewe @ethanewe.bsky.social · 06/07/2026
This paper is now online at @currentbiology.bsky.social. This marks the end of my postdoc and I’ll be joining @imperiallifesci.bsky.social as Imperial College Research Fellow in October! 🎊 🥳🍾 www.cell.com/action/showP...
cell.com
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Yonatan Tzur @tzurlab.bsky.social · 07/07/2026
We identify a new signaling pathway from the neurons to the germline that connects environmental conditions to gametogenic success.
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Yonatan Tzur @tzurlab.bsky.social · 07/07/2026
So proud of our new publication in @currentbiology.bsky.social A wonderful collaborative effort spearheaded by the amazing @ethanewe.bsky.social from @odedrechavi.bsky.social group, with the germline side expertly done by our very own Hanna Achache. bsky.app/profile/oded...
cell.com
Neuronal RNAi and oxygen-sensing circuit shape germline resilience to heat stress
Ewe et al. demonstrate that neuronal small RNAs can modulate germline development under heat stress in Caenorhabditis elegans. They further show that disrupting the oxygen-sensing neural circuit promo...
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Oded Rechavi @odedrechavi.bsky.social · 06/07/2026
Check out Ethan's new paper on how the brain helps protect fertility from heat-induced damage, now out in @currentbiology.bsky.social! Ethan will be opening his own lab in London in a few months - I highly recommend joining him (students/post-docs/technicians) www.sciencedirect.com/science/arti...
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Oded Rechavi @odedrechavi.bsky.social · 15/10/2025
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
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Yonatan Tzur @tzurlab.bsky.social · 25/09/2025
Thanks also to YIsrael Rappaport who started this project, and Hanna Achache ,who pulled us out of the bog. Also, a huge shoutout to the editor and staff of @natcomms.nature.com, who were patient, helpful, and accessible. The most amazing professionals I had the good fortune to work with.
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Yonatan Tzur @tzurlab.bsky.social · 25/09/2025
How do they do it? We are finding out… This work has been almost completely done by the amazing student Roni Falk. I am sorry to see her leave for a postdoc, but I know it is she could become an independent scientist who will contribute a lot to the field of #Fertility.
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Yonatan Tzur @tzurlab.bsky.social · 25/09/2025
In line with the role of lncRNA in promoting meiosis, their level increases as the cells move towards meiosis, and the number of FBF-2 condensates decreases. Thus, the lncRNAs promote meiosis by binding FBF-2 and deactivating it by promoting its condensation.
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Yonatan Tzur @tzurlab.bsky.social · 25/09/2025
Indeed, in the triple lncRNA mutant, transcripts that are repressed by FBF-2 were over-repressed. At least one of the lncRNAs colocalizes with FBF-2 in peri-nuclear condensates and P granules. Deletion of the lncRNAs reduced FBF-2 condensates, and it stayed in the cytoplasm.
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Yonatan Tzur @tzurlab.bsky.social · 25/09/2025
We deleted the genes encoding these three lncRNAs and identified a severe reduction of proliferating germ cells and progeny. This phenotype is similar to overexpression of FBF-2, suggesting that the lncRNAs repress FBF-2.
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Yonatan Tzur @tzurlab.bsky.social · 25/09/2025
LncRNAs are highly expressed in the gonads, but KO of single genes usually results in no obvious phenotype. 3 lncRNAs bind the protein FBF-2 that tilts the balance of germ cells towards stem cell proliferation, and delays meiosis.
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Yonatan Tzur @tzurlab.bsky.social · 25/09/2025
So excited about our recent 📜in @natcomms.nature.com In short, we found 3 lncRNAs that ensure oocyte differentiation by condensing FBF-2, a protein that prevents meiosis entry. And yes, a homologous mechanism probably exists in mammals. #fertility #lncRNA #meiosis nature.com/articles/s41...
nature.com
Three lncRNAs promote PUM protein condensation and germline differentiation - Nature Communications
RNA-binding FBF proteins control germline stem cell differentiation. Here, the authors show that three long non-coding RNAs bind, condense, and thus inhibit FBFs to promote the transition of germline stem cells into meiosis.
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Yonatan Tzur @tzurlab.bsky.social · 11/08/2025
One of the best collaborations we ever had. Brainstorming with ‪@ethanewe.bsky.social‬ whenever a new result came up, was so uplifting and we felt like we boldly go where no one has gone before. Top tier research institutions: grab him while you can!
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Reposted by Yonatan Tzur
Oded Rechavi @odedrechavi.bsky.social · 11/08/2025
WOoo! Hot pre-print alert! 🔥 Check out our new story - We describe evidence that "neuronal oversight" of germline small RNAs prevents sterility and allows lab-domesticated C. elegans to reproduce when temperatures go up (1/2) www.biorxiv.org/content/10.1...
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Yonatan Tzur @tzurlab.bsky.social · 11/08/2025
‪So proud we could take part in this amazing project! Germline/meiosis crowd, you must check this out. A whole new dimension of non-cell autonomous control on gametogenesis. Also, triple shoutout for @ethanewe.bsky.social . A great PI on the way #meiosis #germline #ncRNA
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Reposted by Yonatan Tzur
Erich M. Schwarz @erichmschwarz.bsky.social · 01/08/2025
After 10 years of work, a complete telomere-to-telomere gap-free genome for C. elegans finally exists: it has 106 Mb rather than the textbook 100.3 Mb, and up to 366 additional genes. genome.cshlp.org/content/35/8...
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Yonatan Tzur @tzurlab.bsky.social · 01/08/2025
We go to so many meetings and conferences that most just blend into our memory. But rare ones stand out and truly change the way we think and do science. 👇This was one of those that will stay a part of me.
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Yonatan Tzur @tzurlab.bsky.social · 19/06/2025
A kind invitation by the Cell Biology Department of @charlesuni.cuni.cz brought Israeli scientist stranded in Prague after the #TCTeAC to do what we love best - participate in exciting scientific discussions!
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Yonatan Tzur @tzurlab.bsky.social · 11/06/2025
@barakrotblat.bsky.social : "close you eyes and think about being alive". Me: "is it worth living in glucose starvation?" #TCTeAC
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Itai Yanai @itaiyanai.bsky.social · 11/06/2025
@tzurlab.bsky.social Yonathan Tzur at Woodstock Night Science conference #TCTEAC
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petrahyrossova.bsky.social @petrahyrossova.bsky.social · 11/06/2025
#TCTeAC
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Natanella Illouz-Eliaz @natanellae.bsky.social · 11/06/2025
Balance as a key in life and our biological question. Yonatan Tzur #TCTeAC
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Oded Rechavi @odedrechavi.bsky.social · 10/06/2025
And now Ahmed Elewa with a beautiful development biology talk
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Yonatan Tzur @tzurlab.bsky.social · 10/06/2025
And here it starts: @woodstocknightsci.bsky.social #TCTeAC #theconferencetoendallconferences
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Yonatan Tzur @tzurlab.bsky.social · 10/06/2025
Another great example of the pivotal role of MAPK in reproduction
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Yonatan Tzur @tzurlab.bsky.social · 09/06/2025
With @gazitroi.bsky.social on our way to #theconferencetoendallconferences
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Oded Rechavi @odedrechavi.bsky.social · 17/05/2025
In this conference we couldn't care less where you published your story because 1. we only care if it's interesting and good and 2. participants will discuss unpublished work
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Yonatan Tzur @tzurlab.bsky.social · 22/12/2024
With more research in this direction the former may not be so certain!
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Yonatan Tzur @tzurlab.bsky.social · 02/12/2024
GIF where you're from
media.tenor.com
a falafel token is being launched into the sky
ALT: a falafel token is being launched into the sky
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Yaniv Elkouby @yanivelkouby.bsky.social · 30/11/2024
🔊 We are recruiting PhD students and Postdocs! We are seeking highly motivated, talented, and creative researchers, with strong background in cell and developmental biology, who are looking to spearhead original interdisciplinary investigations, addressing overlooked biology. 1/5
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The Allard lab @allard-lab-ucla.bsky.social · 18/11/2024
The deadline to apply to our Ph.D. program is two weeks away. Apply by December 1st!
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Dr. Verónica Espinoza @verukita1.bsky.social · 18/11/2024
💕 6 tools for illustrating your scientific works! (FREE) 👉Read my Article on Medium here: medium.com/@vespinozag/... #genomic #chemistry #Academic #DataVisualization #postdoc #MachineLearning #DataScience #Bioinformatics #PhD #health #Python #Statistics #Programing #neuroscience #biology #science
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Yonatan Tzur @tzurlab.bsky.social · 18/11/2024
People of Bluesky, let’s get to know each other better: What is one of your favorite movies? Quote share your answer in a gif! 🎥
media.tenor.com
darth vader from star wars is wearing a helmet and cape and holding a light saber .
ALT: darth vader from star wars is wearing a helmet and cape and holding a light saber .
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Yonatan Tzur @tzurlab.bsky.social · 25/10/2023
@tzurlab.bsky.social
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Yonatan Tzur @tzurlab.bsky.social · 16/10/2023
I would like to thank all the friends and colleagues checking in with me.
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Yonatan Tzur @tzurlab.bsky.social · 03/10/2023
mRNA self-assemble into same-sequence condensates in C. elegans oocytes www.cell.com/cell/fulltex...
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