iiinova — where your digital self keeps evolving

Twist Bioscience @twistbioscience.com · 29/09/2026

Blood Cancer Awareness Month spotlight: DNA and RNA each answer different research questions. DNA sequencing maps the mutational landscape. RNA-seq reveals fusion transcripts DNA alone won't show.

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Twist Bioscience @twistbioscience.com · 28/09/2026

September took us around the world. 🌎 From conferences and seminars to workshops and conversations with researchers, the team has been busy connecting with the global biotech community. A few highlights from the road👇

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Twist Bioscience @twistbioscience.com · 25/09/2026

It was a busy week for Twist in Türkiye, with two great events & a memory game: • “Chip to Gene” workshop at Izmir Biomedicine and Genome Center • 10th International Congress of the Molecular Biology Association of Türkiye at Acibadem University in Istanbul @twistbioscience.com

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Twist Bioscience @twistbioscience.com · 24/09/2026

On this 10th anniversary of World Cancer Research Day, we are celebrating those around the world who are working to better understand cancer, develop new therapies, and advance earlier and more precise detection.

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Twist Bioscience @twistbioscience.com · 23/09/2026

We’re proud to contribute DNA to Anthropic and Adaptyv Bio’s protein design competition, helping bring AI-generated designs from the screen into the lab. 🧬 A few highlights: • Claude optimized 30+ biomolecular models, with ~4x average speedups…

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Twist Bioscience @twistbioscience.com · 22/09/2026

How does AI learn to design promising biologics? AI × bio researchers, this one’s for you. Design → Build → Test → Learn → Design AI proposes candidates, the lab tests them, & the resulting data informs the next round. The tighter the loop, the faster models improve!

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Twist Bioscience @twistbioscience.com · 21/09/2026

23% of you are fighting low-input gDNA. Twist TrueAmp Library Prep Kit was built for that fight too. When starting material is scarce, such as ultra-low input or precious and rare tissue samples, your library prep can't be the bottleneck.

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Twist Bioscience @twistbioscience.com · 18/09/2026

Some DNA sequences are tough to make, but Twist Complex Genes can. Examples: 📊 77% average GC, 94% peak 📊 30-base poly-A stretch 📊 13x tandem repeat 📊 Repeats up to 200 bases 📊 99.5% of requested genes made within 15 business days 👉 www.twistbioscience.com/blog/science...

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Twist Bioscience @twistbioscience.com · 17/09/2026

Only about two months until the iGEM Grand Jamboree in Paris! 🧬 🇫🇷 Before you head to Paris, don't forget to claim your team's 20kb of FREE synthetic DNA from Twist Bioscience, available as Gene Fragments or Express Clonal Genes ready to clone. ⏰ Hard Deadline: October 20, 2026

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Twist Bioscience @twistbioscience.com · 16/09/2026

Announcing our agreement with Lilly TuneLab! We are thrilled to be a provider of antibody and characterization services offering preferred pricing for TuneLab users! @elilillyandcompany.bsky.social, @twistbioscience.com Press release: investors.twistbioscience.com/news-release...

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Twist Bioscience @twistbioscience.com · 15/09/2026

It was a packed house for AI × Biotech in San Diego! Great conversation on where AI is already creating value in biotech R&D & where the field is headed next. As AI models generate increasingly novel & complex biological designs, Twist Bioscience helps turn those digital outputs into physical DNA.

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Twist Bioscience @twistbioscience.com · 14/09/2026

September is Blood Cancer Awareness Month, a reminder of how far genomics research has come in revealing signal earlier & understanding cancers at a molecular level. We build the NGS tools behind that research from custom methylation & MRD panels to RNA fusion detection. @twistbioscience.com

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Twist Bioscience @twistbioscience.com · 11/09/2026

High-quality antibodies tailored to your needs because one size doesn’t fit all. Rapidly discover and optimize functional antibodies. In vivo, in vitro, and in silico all under one roof for end-to-end drug discovery solutions: www.twistbioscience.com/twist-biopha...

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Twist Bioscience @twistbioscience.com · 10/09/2026

Some genes are easy, others apparently woke up & chose chaos. Repeats, hairpins, GC-rich regions? Bring on the complexity. Twist Gene Synthesis is designed to tackle challenging sequences with predictable timelines, so your research can focus on the biology, not the synthesis

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Twist Bioscience @twistbioscience.com · 09/09/2026

You told us FFPE is your toughest sample type. We’re not surprised. 57% of respondents named FFPE-degraded tumor tissue their biggest NGS library prep challenge TrueAmp Library Prep Kit was built to help deliver consistent coverage and reduce target dropout: www.twistbioscience.com/next-generat...

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Twist Bioscience @twistbioscience.com · 08/09/2026

AI-designed sequences can look promising computationally but fail in the lab. Our guide explores how DNA synthesis & testing close the AI design-build-test-learn loop, & improve the next round of training data: www.the-scientist.com/adding-the-b... @twistbioscience.com

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Twist Bioscience @twistbioscience.com · 07/09/2026

AI is rewriting the rules of protein design 🧬 @twistbioscience.com & IKP Knowledge Park brought together leaders from AWS, immunitoAI, & PopVax, for a seminar on scaling high-throughput data for biotherapeutic discovery, from de novo antibody generation to gene synthesis at scale.

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Twist Bioscience @twistbioscience.com · 04/09/2026

This Blood Cancer Awareness Month, see how Twist supports researchers across every stage, helping turn genomic complexity into answers that move research forward: www.twistbioscience.com/applications... @twistbioscience.com

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Twist Bioscience @twistbioscience.com · 03/09/2026

Three vendor shows & complex gene launches down! Olivia R. & Heley O. hit back-to-back vendor shows at NYU, Mount Sinai, and the Tri-I last week. It was great to see how many people were genuinely excited about our new complex gene synthesis pipeline. @twistbioscience.com

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Twist Bioscience @twistbioscience.com · 01/09/2026

When AI meets the wet lab, what does that mean for the future? Brendan Smith of TD Cowen + Twist President & COO Patrick Finn discuss AI, drug discovery, big tech, wet-lab validation and the future of biological data: www.tdsecurities.com/ca/en/tdc-ma... @twistbioscience.com

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Twist Bioscience @twistbioscience.com · 28/08/2026

We’re bringing back a Twist classic! Whether you wear them solo or pair them with sandals (we won’t tell anyone 🤫), a fresh pair of Twist socks is the ultimate lab accessory. Learn how to claim your pair here: www.twistbioscience.com/promo/summer... *Terms and conditions apply @twistbioscience.com

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Twist Bioscience @twistbioscience.com · 27/08/2026

5 simple questions, 3 minutes. In the time it takes to brew a cup of coffee you can use our handy guide to configure Twist Gene Synthesis to match your next project's precise requirements. You know we love a good infographic around here, so take a look: www.twistbioscience.com/resources/fl...

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Twist Bioscience @twistbioscience.com · 26/08/2026

🎉 Huge congratulations to our CEO & co-founder Emily Leproust on being named to the 2026 Bioeconomy 500! Her leadership is helping transform the bioeconomy from scientific possibility into real-world projects, products and industries. @twistbioscience.com

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Twist Bioscience @twistbioscience.com · 25/08/2026

Twist independently tested Claude’s AI-designed protein binders! 📊 In <3 weeks, we evaluated 1,260 binders across 15 targets—putting AI-designed proteins to the physical-world test. Do digital designs actually work? See what we found: www.twistbioscience.com/resources/fl... @twistbioscience.com

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Twist Bioscience @twistbioscience.com · 24/08/2026

Howdy, partner! We had an awesome time at this year’s @nucleate.bsky.social Summit in Dallas, TX! 🤠 Twist CSO Colby Souders joined Kavita Kulkarni, Cam Linke & Nirmesh Patel to tackle who will build, fund and shape the datasets AI needs to transform biology. Can’t wait to see everyone again in 2027!

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Twist Bioscience @twistbioscience.com · 20/08/2026

Rejection is tough. Especially when it’s your gene getting rejected. 😬 High GC? Repeats? Homopolymers? Complex sequences? Our new blog explores how Twist tackles complex sequences so you can spend less time redesigning and more time doing science: www.twistbioscience.com/blog/science...

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Twist Bioscience @twistbioscience.com · 19/08/2026

Claude + protein design. 🤩 Common & novel targets were selected to test Claude’s capabilities & out of the 15 selected targets, Claude successfully designed binders against 14 of them! 🎉 We are thrilled to have performed the wet lab validation for this research! (🔗 below) @twistbioscience.com

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Twist Bioscience @twistbioscience.com · 17/08/2026

David R Liu and team published: “AI-redesigned starting points and outcomes enhance protein evolution” www.nature.com/articles/s41... “Mechanistic machine learning for prediction of prime editing outcomes” www.nature.com/articles/s41...

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Twist Bioscience @twistbioscience.com · 14/08/2026

A little Ted Lasso inspiration… BELIEVE in the process. Design it. Build it. Test it. Learn from it. Do it again. From antibody discovery, NGS, & engineering to custom proteins, exome and more, we work to help you accomplish your research goals. We believe in your work @twistbioscience.com

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Twist Bioscience @twistbioscience.com · 13/08/2026

What happens at Twist before your order ships? AI can design it. We build it, express it and characterize it. Biosecurity ensures it is safe…

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Twist Bioscience @twistbioscience.com · 12/08/2026

Protein expression woes? Choosing the right codon optimization algorithm can be a challenge. Our scientists benchmarked 6 free approaches, and LLM-driven algorithms came out on top, with Twist’s new algorithm taking the🥇spot. Read the white paper: www.twistbioscience.com/resources/wh...

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Twist Bioscience @twistbioscience.com · 11/08/2026

Streamline the construction of high-quality DNA libraries for NGS applications… • Detect more low-frequency variants in your samples • Deliver reproducible data across a range of sample types and inputs • Prevent library prep failure • Increase coverage of your target regions

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Twist Bioscience @twistbioscience.com · 10/08/2026

The panel that identified Bundibugyo Ebola is ready to order! The Twist Comprehensive Viral Research Panel detects 3,100+ viral species, including all 4 hemorrhagic fever families endemic to the DRC with up to 10% mismatch tolerance, & integrated One Codex analysis. @twistbioscience.com

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Twist Bioscience @twistbioscience.com · 07/08/2026

In 1 year @resurrectbio.bsky.social achieved what can take traditional breeding 10 yrs Using AI + Twist gene fragments, the team identified & engineered proteins that restore plant immunity against pathogens, bringing faster, more resilient crops within reach: www.twistbioscience.com/resources/ca...

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Twist Bioscience @twistbioscience.com · 06/08/2026

Two of biotech’s greatest leaders chatted at this year’s @synbiobeta.bsky.social conference: Emily Leproust & @johncumbers.bsky.social They discussed everything from @twistbioscience.com’s origin story, wet lab services like antibody discovery & gene shipments, to the impact of AI, & work with AWS

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Twist Bioscience @twistbioscience.com · 03/08/2026

Twist's integrated NGS solutions enable scalable, cost-effective research. Emily Leproust: “Researchers get deeper, more reliable data with fewer sequencing reads per sample compared to both arrays and competing NGS panels.” 👉 www.asianscientist.com/2026/07/spon... @twistbioscience.com

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Twist Bioscience @twistbioscience.com · 30/07/2026

Science is better with good DNA...and good socks.🧦🧬 We had a great time stopping by Caltech to deliver some Twist swag & catch up with longtime customers and Twist users. There's nothing better than seeing how Twist DNA enables research Thanks for the warm welcome, @caltech.edu

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Twist Bioscience @twistbioscience.com · 28/07/2026

🎉 Announcing Complex Genes, now made simple with Twist! ✅ Watch our announcement video ✅ Get to know Complex Genes ✅ See how to keep your projects moving when they involve challenging DNA. @twistbioscience.com

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Twist Bioscience @twistbioscience.com · 27/07/2026

CRISPR gets a power boost from AI-designed ‘molecular scissors’ New work from the Doudna lab! Key takeaways: • Evolution-aware AI designed enzyme variants more likely to retain function. • Engineered RNA-guided nucleases showed improved genome-editing activity… @innovativegenomics.bsky.social

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Twist Bioscience @twistbioscience.com · 24/07/2026

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Twist Bioscience @twistbioscience.com · 23/07/2026

What if a negative test isn't the end of the story? When PCR couldn't identify the virus behind a deadly hemorrhagic fever outbreak, Twist's Comprehensive Viral Panel and whole genome sequencing helped identify the rare Bundibugyo Ebola strain: biopharmaboardroom.com/expert-opini...

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Twist Bioscience @twistbioscience.com · 21/07/2026

MRD Express: Rapid, scalable, and high-performance custom target enrichment for minimal residual disease monitoring: aacrjournals.org/cancerres/ar...

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Twist Bioscience @twistbioscience.com · 21/07/2026

👀 MRD & cancer researchers: This substack from James Hadfield focuses on “exploring the enabling technologies that could fundamentally democratize MRD testing, moving it out of large centralised labs & into community oncology centres near patients.”

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Twist Bioscience @twistbioscience.com · 20/07/2026

Did you see Josh Kerr destroy the men’s mile world record? 3 minutes and 42.66 seconds… He’s fast, and you know what else is fast? Twist Express Genes! 🏃‍♂️ Clonal Genes made in the US to your specifications and shipped to you in as few as 4 days.* www.twistbioscience.com/products/gen...

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Twist Bioscience @twistbioscience.com · 17/07/2026

Anyone following the World Cup? 🏆 If so, respond with an emoji of which team you're rooting for! ⚽ Since Twist is a data-driven company, we conducted an informal poll. Twisters from around the world weighed in about who they are cheering on, and the results are in…

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Twist Bioscience @twistbioscience.com · 14/07/2026

That’s a wrap on the Twist Oncology Roadshow in Singapore & India! Experts in the field gathered to discuss everything from MRD & solid tumors to comprehensive genomic profiling & liquid biopsy. Special thanks to all the panelists, organizers, & attendees! @twistbioscience.com

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Twist Bioscience @twistbioscience.com · 13/07/2026

Fast + efficient + novel antibody development? New from the Institute for Protein Innovation & @harvardmed.bsky.social, led by principal scientist Deepash Kothiwal, reports a novel framework for making synthetic recombinant antibodies that can generate data specifically optimized for ML integration.

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Twist Bioscience @twistbioscience.com · 10/07/2026

Our CEO and co-founder Emily Leproust, and Christine Wormuth, former U.S. secretary of the army, president and CEO of @nti.org discuss supporting scientific innovation while reducing deliberate misuse of AI. Read why it is important here: www.newsweek.com/us-china-mus...

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Twist Bioscience @twistbioscience.com · 09/07/2026

Superior uniformity, deeper insights. The Twist Bioscience NGS advantage Watch our talk led by Maria Harbo at the recent congress of ESHG held in beautiful Gothenburg 🇸🇪 here: m.youtube.com/watch?v=VpF3... @twistbioscience.com

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Twist Bioscience @twistbioscience.com · 08/07/2026

🤖 AI: Here's 10K new DNA designs 🧑‍🔬 Researchers: Great, who can actually make them? At Twist, we're making even the toughest DNA sequences routine so science doesn't have to wait for the impossible. Emily Leproust explains how: www.the-scientist.com/the-power-of...

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