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Jeremiah Tsyporin

@tsyporin.bsky.social
53 followers 94 following 10 posts

Postdoc at Yale, Sestan lab, development and evolution of the cerebral cortex | PhD at University of California, Santa Cruz, Chen lab

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Reposted by Jeremiah Tsyporin
Alex Pollen @brainevodevo.bsky.social · 23/01/2026
1/ Our new study, led by Jingwen Ding, examines the role of transcription factors during human neurogenesis to identify gene regulatory networks influencing cell fate, maturation, and subtype specification www.nature.com/articles/s41...
nature.com
Dissecting gene regulatory networks governing human cortical cell fate - Nature
Systematic screening of transcription factors reveals conserved mechanisms governing cortical radial glia lineage progression across primates and provides a framework for functional dissecti...
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Reposted by Jeremiah Tsyporin
Suel-Kee Kim @suelkeekim.bsky.social · 09/09/2025
Excited to share our recent study on human-specific features of the cerebellum and the unexpected, novel role of zona pellucida protein 2 (ZP2) in synapse development. Grateful to the Sestan lab and all our collaborators for their outstanding contributions. www.biorxiv.org/content/10.1...
biorxiv.org
Human-specific features of the cerebellum and ZP2-regulated synapse development
Understanding the unique features of the human brain compared to non-human primates has long intrigued humankind. The cerebellum refines motor coordination and cognitive functions, contributing to the...
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Reposted by Jeremiah Tsyporin
Suel-Kee Kim @suelkeekim.bsky.social · 10/07/2025
Excited to share our latest work, Mato-Blanco et al., nature.com/articles/s41.... Thanks to the incredible collaboration with Nicola Micali, Rakic lab, Sestan lab, Vaccarino lab @yaleneuro.bsky.social @santperelab.bsky.social @carlocolantuoni.bsky.social
nature.com
Early developmental origins of cortical disorders modeled in human neural stem cells - Nature Communications
The implications of early telencephalic development in cortical disorders remain elusive. Here, the authors define risk gene dynamics and perturbation effects in neural stem cells, revealing vulnerabi...
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Jeremiah Tsyporin @tsyporin.bsky.social · 01/07/2025
Thrilled to present MIND! A model for how the sensorimotor–association axis of the neocortex develops. Huge thanks to the incredible multidisciplinary team who made this happen. www.biorxiv.org/content/10.1...
biorxiv.org
Competing Programs Shape Cortical Sensorimotor-Association Axis Development
The neocortex is organized along a dominant sensorimotor-to-association (S-A) axis, anchored by modality-specific primary sensorimotor areas at one end and transmodal association areas that form distr...
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