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Reposted by Javier Márquez Ruiz

PLOS Biology @plosbiology.org · 09/07/2025

Electrical #BrainStimulation can be used to modulate #brain activity but how does it affect the #CorticalLayers? This study shows that only the deeper layers show phase-dependent changes in local field potential components upon electrical stimulation @plosbiology.org 🧪 plos.io/406W3i5

Top left: Raster plot showing the neural spiking of different types of neurons across layers. The red dots represent excitatory neurons, while the others represent parvalbumin-positive interneurons (blue), somatostatin-positive interneurons (green), and 5-HT3a receptor-positive interneurons (purple), respectively. Top right: Averaged firing rate of excitatory neurons across layers over time, calculated using a 2 ms time bin. Dash lines indicate the onset of flash stimuli. Bottom: Schematic illustration explaining the phase dependency. The synaptic input from the lateral geniculate nucleus (LGN) enters the region adjacent to basal dendrites in deeper layers (gray circle), which are highly responsive to this input (left). When the peak phase of AC flows in a downward direction (middle), the membrane potential in basal dendrites is depolarized, leading to a weaker driving force. It results in weaker (less negative) excitatory postsynaptic current (EPSC) affecting change in LFPs and vice versa during the trough phase.

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Javier Márquez Ruiz @translationalbrainstim.com · 30/06/2025

🧵1/ 🚨 New preprint out! We investigated how cerebellar transcranial direct current stimulation (Cb-tDCS) modulates sensory processing both locally in Crus I/II and distally in primary somatosensory cortex (S1) in awake mice. 📄 www.biorxiv.org/content/10.1...

biorxiv.org

Cerebellar tDCS differentially modulates sensory inputs in somatosensory cortex and cerebellum

Cerebellar transcranial direct-current stimulation (Cb-tDCS) is a promising tool for non-invasive modulation of cerebellar activity and has been proposed for the treatment of cerebellum-related disord...

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Reposted by Javier Márquez Ruiz

Centro Andaluz de Biología del Desarrollo @cabd-upo-csic.bsky.social · 23/04/2025

Amazing postdoctoral position at Pernaute’s lab Fully funded for 3 year by European Research Council (#ERC) grant EARLYFATE #ERCCoG At the #CABD a research center recognized with a national excellence award ‘María de Maeztu’ located in Seville, Spain Share or apply #JobOffer #Postdoctoraljob

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Reposted by Javier Márquez Ruiz

Mark D Humphries @markdhumphries.bsky.social · 08/04/2025

My lab is hiring a pre-doctoral research assistant to work on the neural computations of foraging, seeking common cross-species algorithms. A BBSRC-funded project in collaboration with Matt Apps (Birmingham) & Nathan Lepora (Bristol) Closes May 5th Pls share! jobs.nottingham.ac.uk/vacancy.aspx...

jobs.nottingham.ac.uk

Job Vacancy at the University of Nottingham: Research Assistant (Fixed Term)

We seek a predoctoral research assistant to join the Humphries’ group at the University of Nottingham on a BBSRC-funded project to study the neural basis of foraging, in collaboration with the groups ...

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Reposted by Javier Márquez Ruiz

Ido Aizenbud @idoai.bsky.social · 26/12/2024

Human cortical pyramidal neurons are larger, with more elaborate branching, and distinct nonlinear biophysical properties compared to rat cortical pyramidal neurons. Are they more functionally complex? Could that boost the human brain’s computational power? and is that what makes us human? (1/11)

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Reposted by Javier Márquez Ruiz

Pablo de Olavide @pablodeolavide.upo.es · 28/03/2025

🤖📚 ¿Puede la #IA transformar la #universidad? Hablaremos sobre datos, ética, regulación y futuro en la Gestión Pública Universitaria. 📅 24 de abril 📍 Paraninfo UPO (presencial y online) 🔗 eventos.upo.es/e/164170 #SeminarioUPO #IAEnLaGestión #innovaciónuniversitaria

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Reposted by Javier Márquez Ruiz

Peri Kurshan @pkurshan.bsky.social · 26/03/2025

FACULTY JOB ALERT! The Albert Einstein Dept of Neuroscience is hiring a new assistant professor in any area of neuroscience! We have funds specifically earmarked for this search. #Neuroscience #AcademicJobs #NeuroSky Job just posted: faculty-einstein.icims.com/jobs/17175/f... Please share widely!!

faculty-einstein.icims.com

Albert Einstein College of Medicine | Medical Education | Biomedical Research

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Javier Márquez Ruiz @translationalbrainstim.com · 26/03/2025

🧠 La @pablodeolavide.upo.es acogerá las Jornadas de Estimulación Cerebral 2025 los días 26-27 de mayo. Más de 100 expertos en neurociencia debatirán sobre el futuro de la estimulación cerebral no invasiva. 📍 Paraninfo UPO | 📨 2022aedes@gmail.com #BrainStimulation #tDCS #TMS #NIBS #Neuroscience

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Javier Márquez Ruiz @translationalbrainstim.com · 26/03/2025

🚨 Our revised paper is now available in eLife! 🚨 We show that Purkinje cell orientation determines the polarity-dependent modulation of their firing rate during cerebellar tDCS in awake mice. 🧠✨ Check it out! @elife.bsky.social #tDCS #Cerebellum #PurkinjeCells #BrainStimulation #Neuroscience

doi.org

Somatodendritic orientation determines tDCS-induced neuromodulation of Purkinje cell activity in awake mice

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