tomsextonlab.bsky.social @tomsextonlab.bsky.social · 20/12/2024The perfect addition to our Christmas tree: an ES cell and a cancer cell, knitted by the super talented @cathieerb 000
tomsextonlab.bsky.social @tomsextonlab.bsky.social · 16/12/2024From 2023: out now in @plosbiology.org 👇 TLDR: Transcription CAN directly remodel TADs... in specific contexts. Big congrats to Sanjay and @yousra_zouari who spearheaded the project, and @djost_physbiol +Hossein 010
tomsextonlab.bsky.social @tomsextonlab.bsky.social · 16/12/2024We've now joined BlueSky - we'll try and catch up with all the Twitter/X expats asap 120
tomsextonlab.bsky.social @tomsextonlab.bsky.social · 16/12/2024Out now in @ScienceAdvances 👇 science.org/doi/10.1126/... A great team effort, spearheaded by Angeliki, showing that promoter and enhancer dynamics become homogenized on transcriptional activation, and that loop extrusion and transcription compete to put brakes on chromatinscience.orgTranscription processes compete with loop extrusion to homogenize promoter and enhancer dynamicsGene promoters and enhancers share the same constrained mobilities during transcription, opposing cohesin-mediated loop extrusion. 2202
