Reposted by Tony Zeng
How can we identify circRNAs that might be functional?
Together with @jengreitz.bsky.social, Howard Chang, and team, we found that answering this question is much more challenging than previously thought!
academic.oup.com/nar/article/...
See thread below:
academic.oup.com
Junction-targeting designs limit the application of CRISPR-Cas13d in circular RNA perturbation studies
Abstract. Circular RNAs (circRNAs) are RNA molecules formed through the backsplicing of linear exons. Several thousand have been identified, yet relatively
